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Dong Hwan Ho

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
2013 · Changyoun Kim, Dong-Hwan Ho, et al. · Nature Communications · 893
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Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission
2012 · Eun-Jin Bae, He-Jin Lee, et al. · Journal of Neuroscience · 347
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Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers
2011 · He-Jin Lee, Sung Min Baek, et al. · Experimental & Molecular Medicine · 140
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Lipid Peroxidation Product 4-Hydroxy-2-Nonenal Promotes Seeding-Capable Oligomer Formation and Cell-to-Cell Transfer of α-Synuclein
2012 · Eun-Jin Bae, Dong-Hwan Ho, et al. · Antioxidants and Redox Signaling · 131
Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease
2014 · Dong Hwan Ho, Sanghak Yi, et al. · BioMed Research International · 107
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LRRK2 Kinase Activity Induces Mitochondrial Fission in Microglia via Drp1 and Modulates Neuroinflammation
2018 · Dong Hwan Ho, A Reum Je, et al. · Experimental Neurobiology · 101
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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate
2015 · Hye Jin Yun, Hyejung Kim, et al. · The Journal of Biochemistry · 77
LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25
2013 · Hye Jin Yun, Joohyun Park, et al. · Experimental & Molecular Medicine · 67
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Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression
2015 · Dong Hwan Ho, Hyejung Kim, et al. · Molecular Brain · 62
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LRRK2 impairs autophagy by mediating phosphorylation of leucyl‐tRNA synthetase
2018 · Dong Hwan Ho, Hyejung Kim, et al. · Cell Biochemistry and Function · 54
Detection and Assessment of α-Synuclein Oligomers in the Urine of Parkinson’s Disease Patients
2020 · Daleum Nam, Jee-Young Lee, et al. · Journal of Parkinson s Disease · 44
G2385R and I2020T Mutations Increase LRRK2 GTPase Activity
2016 · Dong Hwan Ho, Jihoon Jang, et al. · BioMed Research International · 42
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Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein
2019 · Dong Hwan Ho, Wongi Seol, et al. · Cell Cycle · 41
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LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress‐Induced Cellular Senescence in Neuronal Cells
2021 · Dong Hwan Ho, Daleum Nam, et al. · Oxidative Medicine and Cellular Longevity · 33
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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease
2018 · Jihoon Jang, Soyeon Jeong, et al. · Parkinson s Disease · 28
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LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss
2022 · Dong-Hwan Ho, Daleum Nam, et al. · Cells · 27
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Enzyme-linked immunosorbent assays for alpha-synuclein with species and multimeric state specificities
2011 · He-Jin Lee, Eun-Jin Bae, et al. · Journal of Neuroscience Methods · 26
G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses
2019 · Dong Hwan Ho, Heajin Lee, et al. · Animal Cells and Systems · 25
Phosphorylation of p53 by LRRK2 induces microglial tumor necrosis factor α-mediated neurotoxicity
2016 · Dong Hwan Ho, Wongi Seol, et al. · Biochemical and Biophysical Research Communications · 25
Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson’s disease
2021 · Daleum Nam, Ami Kim, et al. · Animal Cells and Systems · 18
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The Multifaceted Role of LRRK2 in Parkinson’s Disease
2025 · Dong Hwan Ho, Sun Jung Han, et al. · Brain Sciences · 14
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Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner
2013 · Ji-Min Park, Dong-Hwan Ho, et al. · BMB Reports · 12
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Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts
2023 · Dong Hwan Ho, Hyejung Kim, et al. · International Journal of Molecular Sciences · 10
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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity
2018 · Jihoon Jang, Hakjin Oh, et al. · Animal Cells and Systems · 9
Expression of G2019S LRRK2 in Rat Primary Astrocytes Mediates Neurotoxicity and Alters the Dopamine Synthesis Pathway in N27 Cells via Astrocytic Proinflammatory Cytokines and Neurotrophic Factors
2024 · Dong Hwan Ho, Hyejung Kim, et al. · Current Issues in Molecular Biology · 8
Works count: 46
Citation count: 2,366
H-index: 19
I10-index: 23
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