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Lucille A. Ferrante
Observed names:
L. A. FERRANTE,
L. Ferrante,
Lucille Ferrante
Observed institutions:
Johnson & Johnson (United States),
Memorial Sloan Kettering Cancer Center,
American Chemical Society,
Janssen Scientific Affairs (United States),
Xian Janssen Pharmaceutical Ltd. (China),
Janssen Research & Development (United States),
University of Alabama in Huntsville
show all 7
OpenAlex ID:
A5035889695
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias
2024
·
Min Chul Kwon
, Jan Willem Thuring
, et al.
·
Blood
·
76
Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations
2019
·
Jacob D Soumerai
, Ai Ni
, et al.
·
The Lancet Haematology
·
68
A First-in-Human Phase 1 Study of the Menin-KMT2A (MLL1) Inhibitor JNJ-75276617 in Adult Patients with Relapsed/Refractory Acute Leukemia Harboring KMT2A or NPM1 Alterations
2023
·
Elias Jabbour
, Emma Searle
, et al.
·
Blood
·
52
Bleximenib Dose Optimization and Determination of RP2D from a Phase 1 Study in Relapsed/Refractory Acute Leukemia Patients with KMT2A and NPM1 Alterations
2024
·
Emma Searle
, Christian Recher
, et al.
·
Blood
·
42
First‐in‐human study of JNJ ‐63709178, a CD123 / CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia
2022
·
Michael Boyiadzis
, Pinkal Desai
, et al.
·
Clinical and Translational Science
·
34
PDF
Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination with Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia with KMT2Ar or NPM1 Alterations
2024
·
Christian Recher
, Jenny O'Nions
, et al.
·
Blood
·
27
PDF
Synthesis of mesocyclic and macrocyclic polythioethers using the cesium dithiolate technique
1990
·
William N. Setzer
, Shahrara Afshar
, et al.
·
Heteroatom Chemistry
·
21
Pharmacological Characterization of JNJ-75276617, a Menin-KMT2A Inhibitor, As Targeted Treatment for KMT2A-Altered and NPM1-Mutant Acute Leukemia
2022
·
Min Chul Kwon
, Olivier Querolle
, et al.
·
Blood
·
16
Bleximenib in combination with intensive chemotherapy: A phase 1b study in newly diagnosed Acute Myeloid Leukemia with KMT2A or NPM1 alterations
2025
·
Hartmut Döhner
, Andre Schuh
, et al.
·
Blood
·
14
PDF
Phase 1b study of bleximenib in combination with venetoclax in Acute Myeloid Leukemia with KMT2A or NPM1 alterations
2025
·
Jenny O'Nions
, Andrew Wei
, et al.
·
Blood
·
5
AML-418: Recommended Phase 2 Dose (RP2D) Determination of Bleximenib in Combination With Venetoclax+Azacitidine (VEN+AZA): Phase Ib Study in Newly Diagnosed (ND) and Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) With KMT2A or NPM1 Alterations
2025
·
Andrew H. Wei
, Jordi Esteve Reyner
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
·
4
Preclinical Efficacy of the Menin-KMT2A Inhibitor JNJ-75276617 in Combination with Venetoclax and Azacitidine in AML
2023
·
Min Chul Kwon
, Tinne Verhulst
, et al.
·
Blood
·
4
Bleximenib or placebo in combination with standard induction and consolidation therapy followed by maintenance for the treatment of patients with newly diagnosed KMT2A-rearranged or NPM1-mutant Acute Myeloid Leukemia eligible for intensive chemotherapy: A double-blind Phase 3 study (HOVON 181 AML / AMLSG 37-25)
2025
·
Marc Raaijmakers
, Hartmut Döhner
, et al.
·
Blood
·
3
Prognostic Testing and Treatment Approaches in Patients with Chronic Lymphocytic Leukemia: Clinical Experience from an Interim Analysis of the informCLLTM Real-World Registry
2018
·
Anthony R. Mato
, Jacqueline C. Barrientos
, et al.
·
Blood
·
3
Safety Results from the United States Cohort of the Ibrutinib Early Access Treatment Protocol (EAP: MCL4001) in Patients with Relapsed or Refractory Mantle Cell Lymphoma
2014
·
Peter Martin
, Andre Goy
, et al.
·
Blood
·
3
Bleximenib in Combination with Intensive Chemotherapy: A phase 1b Study in Patients with Newly Diagnosed Acute Myeloid Leukemia with KMT2A or NPM1 Alterations
2026
·
Hartmut Döhner
, Andre C. Schuh
, et al.
·
Transplantation and Cellular Therapy
·
1
Pf383 Prognostic Testing and Treatment Approaches Based on Real‐world Clinical Experience From an Interim Analysis of the Informcll Registry of Patients With Chronic Lymphocytic Leukemia
2019
·
A.R. Mato
, J.C. Barrientos
, et al.
·
HemaSphere
·
1
To the Editor, A multicenter, open-label, early access treatment protocol for ibrutinib in patients with relapsed or refractory mantle cell lymphoma
2019
·
Peter Martin
, Andre Goy
, et al.
·
Journal of Oncology Pharmacy Practice
·
1
Bleximenib in Combination With Intensive Chemotherapy: a Phase 1b Study in Newly Diagnosed Acute Myeloid Leukemia With Kmt2a or Npm1 Alterations
2026
·
Hartmut DÖHNER
, Andre C SCHUH
, et al.
·
Hematology Transfusion and Cell Therapy
Rp2d Determination of Bleximenib in Combination With Ven+aza: Phase 1b Study in Nd & R/r Aml With Kmt2a Type: Oral Presentation Andrew H. Wei Kmt2a/npm1 Npm1alterations
2026
·
Andrew WEIL
, Jordi ESTEVE REYNER
, et al.
·
Hematology Transfusion and Cell Therapy
Camelot-2: A phase 3 Randomized, Double-Blind, Placebo-Controlled, Study of Bleximenib, Venetoclax and Azacitidine for the Treatment of Participants with Newly Diagnosed Acute Myeloid Leukemia Harboring KMT2A rearrangements or NPM1 mutations, Who Are Ineligible for Intensive Chemotherapy
2026
·
Elias Jabbour
, David A. Sallman
, et al.
·
Transplantation and Cellular Therapy
Bleximenib or Placebo in Combination with Standard Induction and Consolidation Therapy Followed By Maintenance for the Treatment of Patients with Newly Diagnosed KMT2A-Rearranged or NPM1-Mutant Acute Myeloid Leukemia Eligible for Intensive Chemotherapy: A Double-Blind phase 3 Study (HOVON 181 AML / AMLSG 37-25)
2026
·
Marc Raaijmakers
, Hartmut Döhner
, et al.
·
Transplantation and Cellular Therapy
POSTER: AML-388 Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination With Intensive Chemotherapy (IC) in Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) with KMT2Ar or NPM1 Alterations
2025
·
Elias Jabbour
, Christian Recher
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
AML-388: Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination With Intensive Chemotherapy (IC) in Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) with KMT2Ar or NPM1 Alterations
2025
·
Elias Jabbour
, Christian Recher
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
POSTER: AML-412 Bleximenib Dose Optimization and Determination of the Recommended Phase 2 Dose (RP2D) From a Phase 1 Study in Patients With Relapsed/Refractory Acute Leukemia (AL) With KMT2A and NPM1 Alterations
2025
·
Hagop M. Kantarjian
, Emma Searle
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
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Works count:
28
Citation count:
373
H-index:
9
I10-index:
9
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