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Jens H. W. Pahl
Observed names:
J. Pahl,
Jens H.W. Pahl,
Jens HW Pahl,
Jens Heinz-Werner Pahl,
Jens Pahl
Observed institutions:
University of Mannheim,
German Cancer Research Center,
Heidelberg University,
Leiden University Medical Center,
Affimed Therapeutics (Germany),
Istituto Ortopedico Rizzoli,
Medizinische Fakultät Mannheim
show all 7
ORCID:
0000-0003-1083-794X
Observed ORCID:
0000-0003-1083-794X
OpenAlex ID:
A5036003709
Tricking the balance: NK cells in anti-cancer immunity
2015
·
Jens Pahl
, Adelheid Cerwenka
·
Immunobiology
·
207
Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
2022
·
Thomas Walle
, Joscha A. Kraske
, et al.
·
Science Advances
·
159
CD16A Activation of NK Cells Promotes NK Cell Proliferation and Memory-Like Cytotoxicity against Cancer Cells
2018
·
Jens H.W. Pahl
, Joachim Koch
, et al.
·
Cancer Immunology Research
·
145
MicroRNA-519a-3p mediates apoptosis resistance in breast cancer cells and their escape from recognition by natural killer cells
2017
·
Christian Breunig
, Jens Pahl
, et al.
·
Cell Death and Disease
·
125
PDF
Anti-EGFR Antibody Cetuximab Enhances the Cytolytic Activity of Natural Killer Cells toward Osteosarcoma
2011
·
Jens H.W. Pahl
, S. Eriaty N. Ruslan
, et al.
·
Clinical Cancer Research
·
111
PDF
Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ
2014
·
Jens HW Pahl
, Kitty MC Kwappenberg
, et al.
·
Journal of Experimental & Clinical Cancer Research
·
101
PDF
Memory-Like NK Cells: Remembering a Previous Activation by Cytokines and NK Cell Receptors
2018
·
Jens H. W. Pahl
, Adelheid Cerwenka
, et al.
·
Frontiers in Immunology
·
99
PDF
Reimagining antibody-dependent cellular cytotoxicity in cancer: the potential of natural killer cell engagers
2022
·
Sheena Pinto
, Jens Pahl
, et al.
·
Trends in Immunology
·
81
KIR downregulation by IL‐12/15/18 unleashes human NK cells from KIR/HLA‐I inhibition and enhances killing of tumor cells
2017
·
Eva‐Maria Ewen
, Jens H.W. Pahl
, et al.
·
European Journal of Immunology
·
79
PDF
The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration
2016
·
Georg Gdynia
, Sven W. Sauer
, et al.
·
Nature Communications
·
71
PDF
Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors
2021
·
Susanne Wingert
, Uwe Reusch
, et al.
·
mAbs
·
70
PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells
2021
·
Tobias Gutting
, Veronika Hauber
, et al.
·
OncoImmunology
·
30
PDF
Expression of the immune regulation antigen CD70 in osteosarcoma
2015
·
Jens HW Pahl
, Susy J Santos
, et al.
·
Cancer Cell International
·
30
PDF
NBAS Variants Are Associated with Quantitative and Qualitative NK and B Cell Deficiency
2021
·
Dominic Lenz
, Jens Pahl
, et al.
·
Journal of Clinical Immunology
·
26
PDF
Antibody-dependent cell lysis by NK cells is preserved after sarcoma-induced inhibition of NK cell cytotoxicity
2013
·
Jens H. W. Pahl
, S. Eriaty N. Ruslan
, et al.
·
Cancer Immunology Immunotherapy
·
19
Adenovirus type 35, but not type 5, stimulates NK cell activation via plasmacytoid dendritic cells and TLR9 signaling
2012
·
Jens H.W. Pahl
, Dirk H.J. Verhoeven
, et al.
·
Molecular Immunology
·
18
CD16A Shedding Regulates Innate Cell Engager‐Induced Serial Killing by Natural Killer Cells
2025
·
Chiara Zambarda
, Karolin Guldevall
, et al.
·
European Journal of Immunology
·
13
PDF
The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS
2025
·
Nanni Schmitt
, Jana-Julia Siegler
, et al.
·
Nature Communications
·
10
PDF
Human innate immune cell crosstalk induces melanoma cell senescence
2020
·
Felix Funck
, Jens Pahl
, et al.
·
OncoImmunology
·
9
AFM28, a Novel Bispecific Innate Cell Engager (ICE ®), Designed to Selectively Re-Direct NK Cell Lysis to CD123+ Leukemic Cells in Acute Myeloid Leukemia and Myelodysplastic Syndrome
2021
·
Jana-Julia Götz
, Jens Pahl
, et al.
·
Blood
·
5
CD16A-Specific Tetravalent Bispecific Immune Cell Engagers Potently Induce Antibody-Dependent Cellular Phagocytosis (ADCP) on Macrophages
2018
·
Susanne Wingert
, Uwe Reusch
, et al.
·
Blood
·
3
NK Cells in Antitumor Immunity
2016
·
Adelheid Cerwenka
, Jens Pahl
·
Elsevier eBooks
·
3
NK cell-mediated tumor cell killing by bispecific innate cell engagers induces ADCC-mediated activation of primary human dendritic cells
2026
·
Lukas Heger
, Tomasz Kaszubowski
, et al.
·
OncoImmunology
·
2
PDF
107 | RESULTS FROM THE DOSE‐FINDING PART OF LuminICE‐203 PHASE 2 STUDY: ACIMTAMIG (AFM13) IN COMBINATION WITH AlloNK (AB‐101) IN PATIENTS WITH RELAPSED/ REFRACTORY HODGKIN LYMPHOMA
2025
·
J. Maakaron
, T. Feldman
, et al.
·
Hematological Oncology
·
2
PDF
AFM13 Is the Most Advanced Bispecific NK-Cell Engaging Antibody in Clinical Development Substantially Enhancing NK-Cell Effector Function and Proliferation
2016
·
Jens Pahl
, Uwe Reusch
, et al.
·
Blood
·
2
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Works count:
42
Citation count:
1,424
H-index:
16
I10-index:
18
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