Author

Iain P. Chessell

Observed names: CHESSELL IP, Chessell, I, Chessell, Iain, Chessell, Iain P, Chessell, Iain P., Chessell, Iain Patrick, I P Chessell, I. Chessell, I. P. CHESSELL, I. P. Chessell, I.P Chessell, I.P. Chessell, IAIN P. CHESSELL, Iain Chessell, Iain P Chessell, Iain Patrick Chessell

Institution: AstraZeneca (United Kingdom)

Observed institutions: AstraZeneca (United Kingdom), University of Leicester, GlaxoSmithKline (United Kingdom), University of Cambridge, The Royal Free Hospital, Hammersmith Hospital, Royal National Orthopaedic Hospital, National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, GlaxoSmithKline Research & Development Limited (United Kingdom), Imperial College London

OpenAlex ID: A5036338186

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

2005 · Iain P. Chessell, Jonathan P. Hatcher, et al. · Pain · 789

Up-Regulation of P2X 4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain

2008 · Lauriane Ulmann, Jon P. Hatcher, et al. · Journal of Neuroscience · 550

COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

2006 · Yiangos Yiangou, Paul Facer, et al. · BMC Neurology · 509

Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis patients

2009 · Stephen E. Gwilym, John R. Keltner, et al. · Arthritis Care & Research · 432

The Voltage-Gated Sodium Channel Na v 1.9 Is an Effector of Peripheral Inflammatory Pain Hypersensitivity

2006 · Fumimasa Amaya, Haibin Wang, et al. · Journal of Neuroscience · 302

Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy

2007 · Paul Facer, Maria A Casula, et al. · BMC Neurology · 282

Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score

2007 · Z. Yilmaz, T. Renton, et al. · Journal of Clinical Neuroscience · 280

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

2008 · Penny C. Staton, Jon P. Hatcher, et al. · Pain · 270

Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors

2000 · B. J. Gu, W. Y. Zhang, et al. · American Journal of Physiology-Cell Physiology · 204

Blockade of Human P2X7 Receptor Function With a Monoclonal Antibody

1998 · G. Buell, I.P. Chessell, et al. · Blood · 201

TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

2017 · Peter Thornton, Jean Sevalle, et al. · EMBO Molecular Medicine · 200

An fMRI study of cerebral processing of brush-evoked allodynia in neuropathic pain patients

2006 · Petra Schweinhardt, Chris Glynn, et al. · NeuroImage · 196

TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons

2008 · U. Anand, W.R. Otto, et al. · Neuroscience Letters · 192

Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons

2008 · Uma Anand, William R. Otto, et al. · Pain · 165

Investigation into the neural correlates of emotional augmentation of clinical pain

2008 · Petra Schweinhardt, Nicola Kalk, et al. · NeuroImage · 160

Pharmacological characterization of ATP‐ and LPS‐induced IL‐1β release in human monocytes

1999 · C B A Grahames, A D Michel, et al. · British Journal of Pharmacology · 151

Cloning and functional characterisation of the mouse P2X7 receptor

1998 · I.P Chessell, J Simon, et al. · FEBS Letters · 147

P2X receptor‐mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint

1998 · E Dowd, D S McQueen, et al. · British Journal of Pharmacology · 142

Localization and Functional Expression of Splice Variants of the P2X2 Receptor

1997 · Joseph Simon, Emma J. Kidd, et al. · Molecular Pharmacology · 142

Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain

2007 · Iain T. Strickland, Jo C. Martindale, et al. · European Journal of Pain · 138

GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain

2005 · Jorge De Alba, Nick M. Clayton, et al. · Pain · 131

Properties of the pore‐forming P2X7 purinoceptor in mouse NTW8 microglial cells

1997 · I P Chessell, A D Michel, et al. · British Journal of Pharmacology · 126

Discovery of 2-[(2,4-Dichlorophenyl)amino]- N -[(tetrahydro- 2 H -pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a Selective CB2 Receptor Agonist for the Treatment of Inflammatory Pain

2007 · Gerard M. P. Giblin, Celestine T. O'Shaughnessy, et al. · Journal of Medicinal Chemistry · 120

Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo

2019 · Darren J. Schofield, Lorraine Irving, et al. · Neurobiology of Disease · 119

Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study

2006 · Pascal F Durrenberger, Paul Facer, et al. · BMC Neurology · 118

Works count: 205

Citation count: 10,140

H-index: 54

I10-index: 114