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Author

Samar Mowafy

Observed names: Mowafy Samar, Mowafy, Samar
Observed institutions: Ain Shams University, Harvard University, University of Washington, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center, Misr International University
ORCID: 0000-0003-1026-9356
Observed ORCID: 0000-0003-1026-9356
OpenAlex ID: A5036417727
Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives
2016 · Samar Mowafy, A. Galanis, et al. · Bioorganic & Medicinal Chemistry · 67
3D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluation
2019 · Mahitab K. Sobhy, Samar Mowafy, et al. · Bioorganic Chemistry · 51
Design, synthesis and in vitro anti-proliferative activity of 4,6-quinazolinediamines as potent EGFR-TK inhibitors
2012 · Samar Mowafy, Nahla A. Farag, et al. · European Journal of Medicinal Chemistry · 50
Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma
2023 · Ahmed I. Khodair, Salwa M. El-Hallouty, et al. · European Journal of Medicinal Chemistry · 49
Structure-guided development of covalent TAK1 inhibitors
2016 · Li Tan, Deepak Gurbani, et al. · Bioorganic & Medicinal Chemistry · 32
Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors
2016 · Li Tan, Deepak Gurbani, et al. · Bioorganic & Medicinal Chemistry · 21
Lead generation of cysteine based mesenchymal epithelial transition (c-Met) kinase inhibitors: Using structure-based scaffold hopping, 3D-QSAR pharmacophore modeling, virtual screening, molecular docking, and molecular dynamics simulation
2022 · Asmaa Raafat, Samar Mowafy, et al. · Computers in Biology and Medicine · 17
Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma
2019 · Shaymaa E. Kassab, Samar Mowafy, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 16
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Molecular design, synthesis and in vitro biological evaluation of thienopyrimidine–hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancer
2021 · Mona M. Abdel-Atty, Nahla A. Farag, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 15
Lead generation of UPPS inhibitors targeting MRSA: Using 3D-QSAR pharmacophore modeling, virtual screening, molecular docking, and molecular dynamic simulations
2024 · Basma M. Qandeel, Samar Mowafy, et al. · BMC Chemistry · 14
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Disease correction in mucopolysaccharidosis type IIIB mice by intraparenchymal or cisternal delivery of a capsid modified AAV8 codon-optimized NAGLU vector
2022 · Courtney J Rouse, Kimberley Hawkins, et al. · Human Molecular Genetics · 8
Biochemical signatures of disease severity in multiple sulfatase deficiency
2023 · Laura A. Adang, Samar Mowafy, et al. · Journal of Inherited Metabolic Disease · 7
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Structural Basis of Selective Human Indoleamine‐2,3‐dioxygenase 1 (hIDO1) Inhibition
2021 · Shaymaa Emam Kassab, Samar Mowafy · ChemMedChem · 5
Insights into flibanserin oxidative stress degradation pathway: in silico – in vitro toxicity assessment of its degradates
2021 · Mohammed F. El-Behairy, Rasha M. Ahmed, et al. · New Journal of Chemistry · 5
Ligand-based discovery of novel N-arylpyrrole derivatives as broad-spectrum antimicrobial agents with antibiofilm and anti-virulence activity
2025 · Basma M. Qandeel, Samar Mowafy, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 4
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Design, synthesis, in silico, and biological evaluation of novel pyrazolopyrimidinone-based estrogen receptor inhibitors
2026 · Sara A. Hesham, Mai I. Shahin, et al. · Future Medicinal Chemistry
Design, synthesis, in silico, and biological evaluation of novel pyrazolopyrimidinone-based estrogen receptor inhibitors
2026 · Hesham, Sara A., Shahin, Mai I., et al. · Figshare
Lead generation of Aurora-A kinase inhibitors: Using 3D-QSAR pharmacophore modeling, virtual screening, and molecular docking
2024 · Sara A. Hesham, Mai I Shahin, et al. · Archives of Pharmaceutical Sciences Ain Shams University
Vegfr2阻害剤のための新規足場のリード発見のための3d-qsar薬理作用団モデリング,仮想スクリーニングおよびドッキング研究:設計,合成および生物学的評価【jst・京大機械翻訳】
2019 · K Sobhy Mahitab, Mowafy Samar, et al. · Bioorganic Chemistry
ChemInform Abstract: Design, Synthesis and in vitro anti‐Proliferative Activity of 4,6‐Quinazolinediamines as Potent EGFR‐TK Inhibitors.
2013 · Samar Mowafy, Nahla A. Farag, et al. · ChemInform
Works count: 25
Citation count: 361
H-index: 10
I10-index: 10
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