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Alexis A. Borisy

Observed names: A A Borisy, A. Borisy, A.A. Borisy, Alexis A Borisy, Alexis Borisy
OpenAlex ID: A5036428059
Synergistic drug combinations tend to improve therapeutically relevant selectivity
2009 · Joseph Lehár, Andrew S Krueger, et al. · Nature Biotechnology · 934
Multicomponent therapeutics for networked systems
2005 · Curtis T. Keith, Alexis A. Borisy, et al. · Nature Reviews Drug Discovery · 769
Systematic discovery of multicomponent therapeutics
2003 · Alexis A. Borisy, Peter J. Elliott, et al. · Proceedings of the National Academy of Sciences · 616
Chemical combination effects predict connectivity in biological systems
2007 · Joseph Lehár, Grant R Zimmermann, et al. · Molecular Systems Biology · 269
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The Novel Combination of Chlorpromazine and Pentamidine Exerts Synergistic Antiproliferative Effects through Dual Mitotic Action
2007 · Margaret S. Lee, Lisa Johansen, et al. · Cancer Research · 113
High‐order combination effects and biological robustness
2008 · Joseph Lehár, Andrew Krueger, et al. · Molecular Systems Biology · 93
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Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis
2007 · T K Kvien, E Fjeld, et al. · Annals of the Rheumatic Diseases · 69
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Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug
2009 · Grant R Zimmermann, William Avery, et al. · Arthritis Research & Therapy · 54
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Adenosine A2A receptor agonists and PDE inhibitors: a synergistic multitarget mechanism discovered through systematic combination screening in B-cell malignancies
2010 · Richard J. Rickles, Laura T. Pierce, et al. · Blood · 36
Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication
2010 · Christopher M Owens, Christina Mawhinney, et al. · Molecular Systems Biology · 34
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Therapeutic selectivity and the multi-node drug target.
2009 · Joseph Lehar, Andrew S Krueger, et al. · PubMed · 23
Erratum: Synergistic drug combinations tend to improve therapeutically relevant selectivity
2009 · Joseph Lehár, Andrew S Krueger, et al. · Nature Biotechnology · 21
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Adenosine A2A and Beta-2 Adrenergic Receptor Agonists: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening
2012 · Richard J. Rickles, Winnie F. Tam, et al. · Molecular Cancer Therapeutics · 19
Multicomponent Therapeutics
2012 · Alexis A. Borisy, Grant R. Zimmermann, et al. · Wiley eBooks · 3
Adenosine A2A and Beta-2 Adrenergic Receptor Agonist Synergy in B-Cell Malignancies: Selectivity, Breadth of Activity and Effects of Chronic Exposure.
2009 · Richard J. Rickles, Winnie F. Tam, et al. · Blood · 1
A2A or Beta-2 Adrenergic Receptor Agonist Synergies Induce Distinct Patterns of Gene Expression Relevant to Multiple Myeloma Cell Survival.
2009 · Winnie F. Tam, Richard J Rickles, et al. · Blood · 1
Data from Adenosine A2A and Beta-2 Adrenergic Receptor Agonists: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening
2023 · Richard J. Rickles, Winnie F. Tam, et al.
Supplementary Figures 1 - 10 from Adenosine A2A and Beta-2 Adrenergic Receptor Agonists: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening
2023 · Richard J. Rickles, Winnie F. Tam, et al.
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Supplementary Figure Legend from Adenosine A2A and Beta-2 Adrenergic Receptor Agonists: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening
2023 · Richard J. Rickles, Winnie F. Tam, et al.
Data from Adenosine A2A and Beta-2 Adrenergic Receptor Agonists: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening
2023 · Richard J. Rickles, Winnie F. Tam, et al.
228 the Synergistic Drug Combination Crx-102 Inhibits Matrix Metalloproteinase Expression in Macrophages and Human Osteoarthritic Chondrocytes
2008 · C.C. Fraser, Y. Wang, et al. · Osteoarthritis and Cartilage
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47 CRx-026: discovery and clinical development of a syncretic anti-mitotic agent with significant anti-cancer activity
2004 · P.J. Elliott, M.S. Lee, et al. · European Journal of Cancer Supplements
Works count: 25
Citation count: 3,055
H-index: 13
I10-index: 13
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