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Nunilo Cremades

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
2012 · Nunilo Cremades, Samuel I.A. Cohen, et al. · Cell · 919
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Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
2017 · Giuliana Fusco, Serene W. Chen, et al. · Science · 676
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Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
2015 · Serene W. Chen, Srdja Drakulic, et al. · Proceedings of the National Academy of Sciences · 484
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Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease
2015 · Emma Deas, Nunilo Cremades, et al. · Antioxidants and Redox Signaling · 369
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A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
2017 · Michele Perni, Céline Galvagnion, et al. · Proceedings of the National Academy of Sciences · 300
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Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents
2018 · Nicole K. Polinski, Laura A. Volpicelli-Daley, et al. · Journal of Parkinson s Disease · 286
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Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of Helicobacter pylori , Selected Anaerobic Bacteria and Parasites, and Campylobacter jejuni
2006 · Paul S. Hoffman, Gary Sisson, et al. · Antimicrobial Agents and Chemotherapy · 248
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells
2021 · Roberta Cascella, Serene W. Chen, et al. · Nature Communications · 239
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Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading
2016 · Marija Iljina, Gonzalo A. Garcia, et al. · Proceedings of the National Academy of Sciences · 227
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Ca2+ is a key factor in α-synuclein-induced neurotoxicity
2016 · Plamena R. Angelova, Marthe H. R. Ludtmann, et al. · Journal of Cell Science · 196
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Structure and Properties of a Complex of α-Synuclein and a Single-Domain Camelid Antibody
2010 · Erwin J. De Genst, Tim Guilliams, et al. · Journal of Molecular Biology · 187
Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria
2008 · Angel L. Pey, Ming Ying, et al. · Journal of Clinical Investigation · 166
Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease
2014 · Gergely Tóth, Shyra J. Gardai, et al. · PLoS ONE · 149
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Defining α-synuclein species responsible for Parkinson’s disease phenotypes in mice
2019 · Jessica M. Froula, Marta Castellana-Cruz, et al. · Journal of Biological Chemistry · 131
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Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies
2022 · Roberta Cascella, Alessandra Bigi, et al. · Cellular and Molecular Life Sciences · 130
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Structural Characteristics of α-Synuclein Oligomers
2016 · N. Cremades, S.W. Chen, et al. · International review of cytology · 123
Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages
2013 · Tim Guilliams, Farah El-Turk, et al. · Journal of Molecular Biology · 118
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Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids
2016 · Mathew H. Horrocks, Steven F. Lee, et al. · ACS Chemical Neuroscience · 115
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Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
2018 · Michele Perni, Patrick Flagmeier, et al. · ACS Chemical Biology · 114
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants
2015 · Laura Tosatto, Mathew H. Horrocks, et al. · Scientific Reports · 112
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On the Mechanism of Nonspecific Inhibitors of Protein Aggregation: Dissecting the Interactions of α-Synuclein with Congo Red and Lacmoid
2009 · Christofer Lendel, Carlos W. Bertoncini, et al. · Biochemistry · 97
Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau
2022 · Pablo Gracia, David Polanco, et al. · Nature Communications · 95
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Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α-Synuclein Oligomers
2015 · Mathew H. Horrocks, Laura Tosatto, et al. · Analytical Chemistry · 93
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The role of water in the primary nucleation of protein amyloid aggregation
2020 · José D. Camino, Pablo Gracia, et al. · Biophysical Chemistry · 87
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Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing
2016 · Jeppe T. Pedersen, Serene W. Chen, et al. · Journal of the American Chemical Society · 80
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Works count: 66
Citation count: 6,906
H-index: 40
I10-index: 50
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