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Andrew J. Macadam

Observed names: A J Macadam, A Macadam, A. J. Macadam, A. MacAdam, A. Macadam, A.J. Macadam, Andrew J Macadam, Andrew MacAdam, Andrew Macadam, Macadam, Andrew
Observed institutions: Scripps Research Institute, University College Hospital, National University of Ireland, Maynooth, Institut Pasteur, Universitat de València, Finnish Institute for Health and Welfare, St Olav's University Hospital, Scripps Clinic, Medicines and Healthcare products Regulatory Agency, University College London, National Institute for Biological Standards and Control, University of Reading
ORCID: 0000-0002-8687-1573
Observed ORCID: 0000-0002-8687-1573
OpenAlex ID: A5036970296
Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus.
1989 · D. J. Filman, R. Syed, et al. · The EMBO Journal · 363
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Recommendations for enterovirus diagnostics and characterisation within and beyond Europe
2018 · Heli Harvala, Eeva Broberg, et al. · Journal of Clinical Virology · 268
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Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence
2020 · Ming Te Yeh, Erika Bujaki, et al. · Cell Host & Microbe · 230
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The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study
2019 · Pierre Van Damme, Ilse De Coster, et al. · The Lancet · 141
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Genetic Basis of Attenuation of the Sabin Type 2 Vaccine Strain of Poliovirus in Primates
1993 · A.J. Macadam, S.R. Pollard, et al. · Virology · 140
The Evolutionary Pathway to Virulence of an RNA Virus
2017 · Adi Stern, Ming Te Yeh, et al. · Cell · 131
Reversion of the attenuated and temperature-sensitive phenotypes of the sabin type 3 strain of poliovirus in vaccinees
1989 · A.J. Macadam, C. Arnold, et al. · Virology · 124
Poliovirus-specific CD4+ Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor.
1995 · B P Mahon, K Katrak, et al. · The Journal of Experimental Medicine · 121
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Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
2017 · Johanna Marsian, Helen Fox, et al. · Nature Communications · 120
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Transmission Networks and Population Turnover of Echovirus 30
2008 · E. C. McWilliam Leitch, J. Bendig, et al. · Journal of Virology · 111
Mapping of mutations associated with neurovirulence in monkeys infected with Sabin 1 poliovirus revertants selected at high temperature
1990 · C Christodoulou, F Colbere-Garapin, et al. · Journal of Virology · 106
Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization
2020 · Jennifer L. Konopka-Anstadt, Ray Campagnoli, et al. · npj Vaccines · 98
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Rational Design of Genetically Stable, Live-Attenuated Poliovirus Vaccines of All Three Serotypes: Relevance to Poliomyelitis Eradication
2006 · Andrew J. Macadam, Geraldine Ferguson, et al. · Journal of Virology · 89
Evolution of the Sabin type 1 poliovirus in humans: characterization of strains isolated from patients with vaccine-associated paralytic poliomyelitis
1997 · M M Georgescu, J Balanant, et al. · Journal of Virology · 81
Correlation of RNA secondary structure and attenuation of Sabin vaccine strains of poliovirus in tissue culture
1992 · A.J. Macadam, G. Ferguson, et al. · Virology · 71
Role of mutations G-480 and C-6203 in the attenuation phenotype of Sabin type 1 poliovirus
1995 · A McGoldrick, A J Macadam, et al. · Journal of Virology · 68
Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3
2023 · Ming Te Yeh, Matthew Smith, et al. · Nature · 65
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Role for poliovirus protease 2A in cap independent translation.
1994 · A.J. Macadam, G. Ferguson, et al. · The EMBO Journal · 63
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Genetically Thermo-Stabilised, Immunogenic Poliovirus Empty Capsids; a Strategy for Non-replicating Vaccines
2017 · Helen Fox, Sarah Knowlson, et al. · PLoS Pathogens · 58
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Genetic Basis of Attenuation of the Sabin Oral Poliovirus Vaccines
1993 · P.D. Minor, A.J. Macadam, et al. · Biologicals · 56
The Picornaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens
2022 · Raul Andino, Karla Kirkegaard, et al. · The Journal of Infectious Diseases · 53
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An assembly defect as a result of an attenuating mutation in the capsid proteins of the poliovirus type 3 vaccine strain
1991 · A J Macadam, G Ferguson, et al. · Journal of Virology · 49
The 5′ noncoding region and virulence of poliovirus vaccine strains
1994 · Andrew J. Macadam, David M. Stone, et al. · Trends in Microbiology · 44
Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis
2017 · Ling Shen, Crystal Y. Chen, et al. · Journal of Virology · 42
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Genetic Characterization of Novel Oral Polio Vaccine Type 2 Viruses During Initial Use Phase Under Emergency Use Listing — Worldwide, March–October 2021
2022 · Javier Martin, Cara C. Burns, et al. · MMWR Morbidity and Mortality Weekly Report · 41
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Works count: 59
Citation count: 3,162
H-index: 28
I10-index: 42
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