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Natalie A. Hawryluk

Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures1
2001 · Perry S. Corbin, Steven C. Zimmerman, et al. · Journal of the American Chemical Society · 246
Identification and Characterization of a Novel Class of Interleukin-1 Post-Translational Processing Inhibitors
2001 · David G. Perregaux, Patricia McNiff, et al. · Journal of Pharmacology and Experimental Therapeutics · 226
A New Chiral Rh(II) Catalyst for Enantioselective [2 + 1]-Cycloaddition. Mechanistic Implications and Applications
2004 · Yan Lou, Manabu Horikawa, et al. · Journal of the American Chemical Society · 217
Formal Synthesis of (±)-Guanacastepene A
2003 · Bo Shi, Natalie A. Hawryluk, et al. · The Journal of Organic Chemistry · 63
Synthesis of (−)-Dysiherbaine
2000 · Barry B. Snider, Natalie A. Hawryluk · Organic Letters · 54
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists
2013 · Michael A. Letavic, Brian Lord, et al. · ACS Medicinal Chemistry Letters · 53
Synthesis of the Hydroazulene Ring System of Guanacastepene
2001 · Barry B. Snider, Natalie A. Hawryluk · Organic Letters · 47
Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene
2000 · Natalie A. Hawryluk, Barry B. Snider · The Journal of Organic Chemistry · 33
Discovery of a novel series of selective HCN1 blockers
2011 · Kelly J. McClure, Michael Maher, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites
2012 · Mark S. Tichenor, John M. Keith, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis
2021 · Rokeya Tasneen, Deborah S. Mortensen, et al. · Antimicrobial Agents and Chemotherapy · 20
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB
2020 · Ruslana Bryk, Shashirekha Mundhra, et al. · PLoS Pathogens · 17
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Macrofilaricides: An Unmet Medical Need for Filarial Diseases
2020 · Natalie A. Hawryluk · ACS Infectious Diseases · 15
Global Health Priority Box─Proactive Pandemic Preparedness
2024 · Anna Adam, Dominique Besson, et al. · ACS Infectious Diseases · 13
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists
2010 · Natalie A. Hawryluk, Jeffrey E. Merit, et al. · Bioorganic & Medicinal Chemistry Letters · 13
1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase
2014 · John M. Keith, Natalie Hawryluk, et al. · Bioorganic & Medicinal Chemistry Letters · 12
Evidence for dispensability of protein kinase R in host control of tuberculosis
2018 · Shashirekha Mundhra, Ruslana Bryk, et al. · European Journal of Immunology · 11
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Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization
2022 · Natalie Hawryluk, Li Zhiru, et al. · International Journal for Parasitology Drugs and Drug Resistance · 7
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1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties
2010 · Alec D. Lebsack, Jason C. Rech, et al. · Bioorganic & Medicinal Chemistry Letters · 7
Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis
2018 · Sreedhar R. Tummalapalli, Rohit Bhat, et al. · ACS Medicinal Chemistry Letters · 6
Abstract 15822: Cardiac Effects of EDG-7500, a Novel Cardiac Sarcomere Regulator: In vitro and in vivo Evidence for Slowing Isovolumic Contraction and Improved Ventricular Compliance
2023 · Carlos L Del Rio, Weikang Ma, et al. · Circulation · 4
Synthesis of covalent [14C]‐labeled diarylsulfonylurea (DASU) inhibitors of the processing and release of IL‐1
2002 · J. F. Eggler, C. A. Gabel, et al. · Journal of Labelled Compounds and Radiopharmaceuticals · 4
Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections
2022 · Natalie Hawryluk, Dale Robinson, et al. · Journal of Medicinal Chemistry · 3
Abstract 15612: EDG-7500, a Novel Cardiac Sarcomere Regulator That Preserves Intrinsic Myosin-Motor Function, Improves Cardiac Function and Reserve in a Minipig Model of Hypertrophic Cardiomyopathy
2023 · Carlos L Del Rio, Cassady Rupert, et al. · Circulation · 2
Edg-002, a Novel Targeted Sarcomere Regulator Preserves Intrinsic Myosin-motor Function, Blunts Hypercontractility and Eliminates Lvot Obstruction in Cats With Hypertrophic Cardiomyopathy: in Vitro and in Vivo Evidence
2023 · Joanna Kaplan, Sarah Lehman, et al. · Journal of the American College of Cardiology · 2
Works count: 41
Citation count: 1,138
H-index: 13
I10-index: 17
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