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Poorval M. Joshi
Observed name:
Poorval Joshi
Institution:
Freenome (United States)
Observed institutions:
Mayo Clinic,
Johns Hopkins University,
New York Medical College,
Johns Hopkins Medicine,
Yale Cancer Center,
Yale University,
Freenome (United States),
Johns Hopkins Hospital,
Sidney Kimmel Comprehensive Cancer Center
show all 9
ORCID:
0000-0001-7886-9994
Observed ORCID:
0000-0001-7886-9994
OpenAlex ID:
A5037563089
Ovarian Cancer-associated Mutations Disable Catalytic Activity of CDK12, a Kinase That Promotes Homologous Recombination Repair and Resistance to Cisplatin and Poly(ADP-ribose) Polymerase Inhibitors
2014
·
Poorval M. Joshi
, Shari L. Sutor
, et al.
·
Journal of Biological Chemistry
·
206
PDF
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
2020
·
Yimeng Gao
, Radovan Vasic
, et al.
·
Immunity
·
187
PDF
SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells
2018
·
Yang Liang
, Toma Tebaldi
, et al.
·
Leukemia
·
99
Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies
2022
·
Giulia Biancon
, Poorval Joshi
, et al.
·
Molecular Cell
·
79
Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination
2015
·
Amelia M. Huehls
, Catherine J. Huntoon
, et al.
·
Molecular Pharmacology
·
53
How do messenger RNA splicing alterations drive myelodysplasia?
2017
·
Poorval Joshi
, Stephanie Halene
, et al.
·
Blood
·
35
PDF
Visualization of herpes simplex virus type 1 virions using fluorescent colors
2016
·
Lyns Etienne
, Poorval Joshi
, et al.
·
Journal of Virological Methods
·
19
Incorporation of the Kaposi’s sarcoma-associated herpesvirus capsid vertex-specific component (CVSC) into self-assembled capsids
2017
·
Peter Grzesik
, Derek MacMath
, et al.
·
Virus Research
·
10
Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq
2022
·
Giulia Biancon
, Emma Busarello
, et al.
·
STAR Protocols
·
4
PDF
Mettl3 Mediated m6A Modification Is Essential in Fetal Hematopoiesis
2018
·
Yimeng Gao
, Radovan Vasic
, et al.
·
Blood
·
3
Clinical performance of an improved colorectal cancer (CRC) screening blood test.
2026
·
Aasma Shaukat
, Alexander F. Lovejoy
, et al.
·
Journal of Clinical Oncology
·
1
PDF
Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure
2019
·
Yimeng Gao
, Radovan Vasic
, et al.
·
Blood
·
1
U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex
2019
·
Giulia Biancon
, Poorval Joshi
, et al.
·
Blood
·
1
Abstract 1107: Development and performance of a multiomics lung cancer screening blood test
2026
·
Ofer Shapira
, Alexander F. Lovejoy
, et al.
·
Cancer Research
U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies
2021
·
Giulia Biancon
, Poorval Joshi
, et al.
·
Blood
High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies
2020
·
Giulia Biancon
, Poorval Joshi
, et al.
·
Blood
Abstract POSTER-BIOL-1325: Ovarian cancer-associated CDK12 mutations disable its kinase activity and cause defects in homologous recombination
2015
·
Poorval M. Joshi
, Shari L. Sutor
, et al.
·
Clinical Cancer Research
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Works count:
17
Citation count:
698
H-index:
8
I10-index:
8
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