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Matthias Schmidt

Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases
2017 · Matthias Schmidt, Alexander Rohe, et al. · Molecules · 226
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Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis
2016 · Tino Heimburg, Alokta Chakrabarti, et al. · Journal of Medicinal Chemistry · 129
Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity
2017 · Tino Heimburg, Fiona R. Kolbinger, et al. · Journal of Medicinal Chemistry · 91
Application of Docking and QM/MM-GBSA Rescoring to Screen for Novel Myt1 Kinase Inhibitors
2014 · Kanin Wichapong, Alexander Rohe, et al. · Journal of Chemical Information and Modeling · 82
New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance
2007 · Matthias Schmidt, Johannes Ungvári, et al. · Bioorganic & Medicinal Chemistry · 57
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity
2021 · Hany S. Ibrahim, Mohamed Abdelsalam, et al. · International Journal of Molecular Sciences · 50
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Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties
2022 · Ping Sun, Jing Wang, et al. · Journal of Medicinal Chemistry · 49
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Solution Structure of a Functional Biomimetic and Mechanistic Implications for Nickel Superoxide Dismutases
2008 · Matthias Schmidt, Stefan Zahn, et al. · ChemBioChem · 48
Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity
2022 · Salma Darwish, Ehab Ghazy, et al. · International Journal of Molecular Sciences · 45
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4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells
2024 · Wagdy M. Eldehna, Mohamed Fares, et al. · Journal of Medicinal Chemistry · 39
Identification of HDAC10 Inhibitors that Modulate Autophagy in Transformed Cells
2022 · Patrik Zeyen, Yanira Zeyn, et al. · European Journal of Medicinal Chemistry · 36
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Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1
2020 · Ehab Ghazy, Patrik Zeyen, et al. · European Journal of Medicinal Chemistry · 34
Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins
2024 · Melisa Halilovic, Mohamed Abdelsalam, et al. · Leukemia · 29
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Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase
2024 · Abdallah M. Alfayomy, Ramy Ashry, et al. · European Journal of Medicinal Chemistry · 29
Synthesis and Biochemical Characterization of New Phenothiazines and Related Drugs as MDR Reversal Agents
2008 · Matthias Schmidt, Marlen Teitge, et al. · Archiv der Pharmazie · 26
Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1
2018 · Abdulkarim Najjar, Charlott Platzer, et al. · European Journal of Medicinal Chemistry · 25
Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis
2018 · Theresa Bayer, Alokta Chakrabarti, et al. · ChemMedChem · 24
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First total synthesis of 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol—a glycoglycerolipid of a marine alga with a high inhibitor activity against human Myt1-kinase
2009 · Christiane Göllner, Claudia Philipp, et al. · Carbohydrate Research · 23
Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II
2018 · Charlott Platzer, Abdulkarim Najjar, et al. · Bioorganic & Medicinal Chemistry · 19
Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum
2016 · B. Sauer, T.S. Skinner-Adams, et al. · European Journal of Medicinal Chemistry · 19
Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay
2012 · Alexander Rohe, Christiane Göllner, et al. · European Journal of Medicinal Chemistry · 19
In vitro and in silico studies on substrate recognition and acceptance of human PKMYT1, a Cdk1 inhibitory kinase
2011 · Alexander Rohe, Frank Erdmann, et al. · Bioorganic & Medicinal Chemistry Letters · 19
A Fluorescence Anisotropy–Based Myt1 Kinase Binding Assay
2013 · Alexander Rohe, Claudia Henze, et al. · Assay and Drug Development Technologies · 18
Binding Free Energy (BFE) Calculations and Quantitative Structure–Activity Relationship (QSAR) Analysis of Schistosoma mansoni Histone Deacetylase 8 (smHDAC8) Inhibitors
2021 · Conrad V. Simoben, Ehab Ghazy, et al. · Molecules · 17
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Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis
2021 · Ehab Ghazy, Tino Heimburg, et al. · European Journal of Medicinal Chemistry · 14
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Works count: 55
Citation count: 1,240
H-index: 19
I10-index: 26
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