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Carien Dekker

The interaction network of the chaperonin CCT
2008 · Carien Dekker, Peter C Stirling, et al. · The EMBO Journal · 217
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Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition
2021 · Carien Dekker, Henri Mattes, et al. · Journal of Molecular Biology · 183
The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins
2010 · Carien Dekker, S Mark Roe, et al. · The EMBO Journal · 100
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Crystal structure of SecB from Escherichia coli
2003 · Carien Dekker, Ben de Kruijff, et al. · Journal of Structural Biology · 70
Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors
2024 · Juraj Velcicky, Philipp Janser, et al. · Journal of Medicinal Chemistry · 53
Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor
2025 · Dong-Ming Shen, Kate F. Byth, et al. · Journal of Medicinal Chemistry · 49
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Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome
2024 · Angela Mackay, Juraj Velcicky, et al. · Journal of Medicinal Chemistry · 46
Yeast Phosducin-Like Protein 2 Acts as a Stimulatory Co-Factor for the Folding of Actin by the Chaperonin CCT via a Ternary Complex
2009 · Elizabeth A. McCormack, Gabriel M. Altschuler, et al. · Journal of Molecular Biology · 36
Lessons from ten years of crystallization experiments at the SGC
2016 · Jia Tsing Ng, Carien Dekker, et al. · Acta Crystallographica Section D Structural Biology · 32
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Using textons to rank crystallization droplets by the likely presence of crystals
2014 · Jia Tsing Ng, Carien Dekker, et al. · Acta Crystallographica Section D Biological Crystallography · 28
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On the evolutionary origin of the chaperonins
2010 · Carien Dekker, Keith R. Willison, et al. · Proteins Structure Function and Bioinformatics · 28
Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain
2019 · Randall McNally, Qing Li, et al. · ACS Chemical Biology · 27
Inhibitory and neutral antibodies to Plasmodium falciparum MSP119 form ring structures with their antigen
2004 · Carien Dekker, Chairat Uthaipibull, et al. · Molecular and Biochemical Parasitology · 18
A single amino acid residue is responsible for species‐specific incompatibility between CCT and α‐actin
2009 · G.M. Altschuler, C. Dekker, et al. · FEBS Letters · 17
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A phospho-harmonic orchestra plays the NLRP3 score
2023 · Frédéric Bornancin, Carien Dekker · Frontiers in Immunology · 10
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On the role of the chaperonin CCT in the just‐in‐time assembly process of APC/CCdc20
2009 · Carien Dekker · FEBS Letters · 10
Crystals of Acetylated SecB Diffract to 2.3-Å Resolution
1999 · Carien Dekker, Ben de Kruijff, et al. · Journal of Structural Biology · 4
Discovery and Characterization of Zilurgisertib, a Potent and Selective Inhibitor of Activin Receptor-like Kinase-2 (ALK2) for the Treatment of Fibrodysplasia Ossificans Progressiva
2025 · Thomas Ullrich, Sabine Guth, et al. · ACS Medicinal Chemistry Letters · 3
Biophysical Characterization of the Influence of Salt on Tetrameric SecB
2001 · Carien Dekker, Bogos Agianian, et al. · Biophysical Journal · 3
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An Industrial Perspective on Protein–Ligand Complex Crystallization
2020 · Carien Dekker, Arnaud Goepfert · Wiley eBooks · 2
Vapour-diffusion protein crystallization in newly designed pore strips
2004 · Carien Dekker, Lesley Haire, et al. · Journal of Applied Crystallography · 2
Correction to “Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor”
2025 · Dong-Ming Shen, Kate F. Byth, et al. · Journal of Medicinal Chemistry · 1
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Cocrystal structure of Zilurgisertib bound to the ALK2-FKBP12 complex
2025 · C. Dekker · Worldwide Protein Data Bank
PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000512a
2019 · J.K. Petrick, E.R. Nelson, et al. · Worldwide Protein Data Bank
PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000276a
2019 · J.K. Petrick, E.R. Nelson, et al. · Worldwide Protein Data Bank
Works count: 66
Citation count: 939
H-index: 14
I10-index: 16
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