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Murat Cirit
Observed names:
Cirit Murat,
Cirit, Murat,
M Cirit,
M. Cirit
Observed institutions:
North Carolina State University,
CN Bio Innovations (United Kingdom),
DigiM Solution,
Massachusetts Institute of Technology
ORCID:
0000-0002-6922-223X
Observed ORCID:
0000-0002-6922-223X
OpenAlex ID:
A5037960640
Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies
2018
·
Collin D. Edington
, Wen Li Kelly Chen
, et al.
·
Scientific Reports
·
478
PDF
Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies
2017
·
Nikolaos Tsamandouras
, Wen Li Kelly Chen
, et al.
·
The AAPS Journal
·
221
PDF
Integrated gut/liver microphysiological systems elucidates inflammatory inter‐tissue crosstalk
2017
·
Wen L.K. Chen
, Collin Edington
, et al.
·
Biotechnology and Bioengineering
·
168
PDF
Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
2016
·
N. Tsamandouras
, T. Kostrzewski
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
119
PDF
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
2010
·
Greg Buhrman
, V. S. Senthil Kumar
, et al.
·
Journal of Biological Chemistry
·
88
Systematic Quantification of Negative Feedback Mechanisms in the Extracellular Signal-regulated Kinase (ERK) Signaling Network
2010
·
Murat Cirit
, Chun-Chao Wang
, et al.
·
Journal of Biological Chemistry
·
84
PDF
PI3K‐dependent cross‐talk interactions converge with Ras as quantifiable inputs integrated by Erk
2009
·
Chun‐Chao Wang
, Murat Cirit
, et al.
·
Molecular Systems Biology
·
84
PDF
Maximizing the impact of microphysiological systems with in vitro – in vivo translation
2018
·
Murat Cirit
, Cynthia L. Stokes
·
Lab on a Chip
·
70
PDF
Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS)
2017
·
Christian Maass
, Cynthia L. Stokes
, et al.
·
Integrative Biology
·
70
PDF
Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System
2017
·
Ujjal Sarkar
, Kodihalli C. Ravindra
, et al.
·
Drug Metabolism and Disposition
·
69
PDF
Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
2019
·
Christian Maass
, Nathan B. Sorensen
, et al.
·
CPT Pharmacometrics & Systems Pharmacology
·
68
PDF
Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells
2010
·
Murat Cirit
, Matej Krajcovic
, et al.
·
PLoS Computational Biology
·
59
PDF
Data‐driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states
2014
·
Shoeb Ahmed
, Kyle G Grant
, et al.
·
Molecular Systems Biology
·
57
Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi‐MPS Integration
2015
·
J Yu
, NA Cilfone
, et al.
·
CPT Pharmacometrics & Systems Pharmacology
·
52
PDF
Inflammatory cytokines and mechanical injury induce post-traumatic osteoarthritis-like changes in a human cartilage-bone-synovium microphysiological system
2022
·
Garima Dwivedi
, Lisa Flaman
, et al.
·
Arthritis Research & Therapy
·
49
PDF
Physiome‐on‐a‐Chip: The Challenge of “Scaling” in Design, Operation, and Translation of Microphysiological Systems
2015
·
CL Stokes
, M Cirit
, et al.
·
CPT Pharmacometrics & Systems Pharmacology
·
49
PDF
Analysis of an Integrated Human Multiorgan Microphysiological System for Combined Tolcapone Metabolism and Brain Metabolomics
2019
·
Xin Wang
, Murat Cirit
, et al.
·
Analytical Chemistry
·
47
A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics Applications
2023
·
Shiny Amala Priya Rajan
, Jason Sherfey
, et al.
·
The AAPS Journal
·
33
PDF
Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies
2018
·
Christian Maass
, Matthew Dallas
, et al.
·
Scientific Reports
·
27
PDF
Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation
2011
·
Murat Cirit
, Jason M. Haugh
·
Biochemical Journal
·
23
Quantitative systems pharmacology in neuroscience: Novel methodologies and technologies
2021
·
Peter Bloomingdale
, Tatiana Karelina
, et al.
·
CPT Pharmacometrics & Systems Pharmacology
·
20
PDF
Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling
2019
·
Sara G. Mina
, Begum Alaybeyoglu
, et al.
·
Frontiers in Big Data
·
20
PDF
Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132
2012
·
Murat Cirit
, Kyle G. Grant
, et al.
·
PLoS ONE
·
19
PDF
Utilization of a human Liver Tissue Chip for drug-metabolizing enzyme induction studies of perpetrator and victim drugs
2024
·
Shivam Ohri
, Paarth Parekh
, et al.
·
Drug Metabolism and Disposition
·
14
Human cartilage-bone-synovium microphysiological system to study ptoa pathogenesis and treatment on earth and in space
2019
·
G. Dwivedi
, L. Flaman
, et al.
·
Osteoarthritis and Cartilage
·
9
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Works count:
64
Citation count:
2,023
H-index:
20
I10-index:
24
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