Author

Yasuyuki Ohtake

Observed names: Y Ohtake, Y. Ohtake, Yasuyuki OHTAKE

Institutions: Asahi Breweries (Japan), Asahi Group Foods, Ltd. (Japan)

Observed institutions: Jikei University School of Medicine, National Institutes of Health, Lovelace Respiratory Research Institute, Harvard University, Hirosaki University, Tokyo University of Pharmacy and Life Sciences, Tohoku University, Kyoto University, National Institute of Diabetes and Digestive and Kidney Diseases, Asahi Breweries (Japan), Dana-Farber Cancer Institute, National Institute of Health Sciences, Asahi Group Foods, Ltd. (Japan)

OpenAlex ID: A5038013342

Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption

2007 · Hiroshi Sugiyama, Yoko Akazome, et al. · Journal of Agricultural and Food Chemistry · 333

Apple Procyanidin Oligomers Absorption in Rats after Oral Administration: Analysis of Procyanidins in Plasma Using the Porter Method and High-Performance Liquid Chromatography/Tandem Mass Spectrometry

2006 · Toshihiko Shoji, Saeko Masumoto, et al. · Journal of Agricultural and Food Chemistry · 248

Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells.

2003 · Dharminder Chauhan, Guilan Li, et al. · PubMed · 228

A New Antioxidative 1,3-Benzodioxole fromMelissa officinalis

1998 · Motoyuki Tagashira, Yasuyuki Ohtake · Planta Medica · 185

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

2003 · Dharminder Chauhan, Guilan Li, et al. · Blood · 166

A Novel Gene, CRR9, Which Was Up-Regulated in CDDP-Resistant Ovarian Tumor Cell Line, Was Associated with Apoptosis

2001 · Kazue Yamamoto, Aikou Okamoto, et al. · Biochemical and Biophysical Research Communications · 156

Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3

2007 · T. Miura, M. Chiba, et al. · Carcinogenesis · 142

Molecular cloning of the γ‐glutamylcysteine synthetase gene of Saccharomyces cerevisiae

1991 · Yasuyuki Ohtake, Seizou Yabuuchi · Yeast · 125

Yeast Virus Propagation Depends Critically on Free 60S Ribosomal Subunit Concentration

1995 · Yasuyuki Ohtake, Reed B. Wickner · Molecular and Cellular Biology · 106

PDF

Apple Polyphenols Influence Cholesterol Metabolism in Healthy Subjects with Relatively High Body Mass Index

2007 · Yoko Nagasako-Akazome, Tomomasa Kanda, et al. · Journal of Oleo Science · 102

PDF

Apple (Malus pumila) procyanidins fractionated according to the degree of polymerization using normal-phase chromatography and characterized by HPLC-ESI/MS and MALDI-TOF/MS

2005 · Toshihiko Shoji, Saeko Masumoto, et al. · Journal of Chromatography A · 100

Allelic imbalance and mutations of the PTEN gene in ovarian cancer

2000 · Misato Saito, Aikou Okamoto, et al. · International Journal of Cancer · 89

Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance

2001 · Kazue Yamamoto, Aikou Okamoto, et al. · Cancer Letters · 82

Inflammatory Responses of Gingival Epithelial Cells Stimulated With Porphyromonas gingivalis Vesicles Are Inhibited by Hop‐Associated Polyphenols

2007 · Yurong Kou, Hiroaki Inaba, et al. · Journal of Periodontology · 61

Orally administered apple procyanidins protect against experimental inflammatory bowel disease in mice

2008 · Yasuo Yoshioka, Hiroshi Akiyama, et al. · International Immunopharmacology · 58

Mak21p of Saccharomyces cerevisiae, a Homolog of Human CAATT-binding Protein, Is Essential for 60 S Ribosomal Subunit Biogenesis

1998 · Herman K. Edskes, Yasuyuki Ohtake, et al. · Journal of Biological Chemistry · 40

PDF

Identification of Hop Polyphenolic Components Which Inhibit Prostaglandin E2 Production by Gingival Epithelial Cells Stimulated with Periodontal Pathogen

2008 · Hiroaki Inaba, Motoyuki Tagashira, et al. · Biological and Pharmaceutical Bulletin · 39

PDF

Procyanidin C1 from Apple Extracts Inhibits FcεRI-Mediated Mast Cell Activation

2008 · Nobuhiro Nakano, Chiharu Nishiyama, et al. · International Archives of Allergy and Immunology · 38

Mithramycin Represses MDR1 Gene Expression in Vitro, Modulating Multidrug Resistance.

2000 · Motoyuki TAGASHIRA, Takanori KITAGAWA, et al. · Biological and Pharmaceutical Bulletin · 38

PDF

Administration of Apple Polyphenol Supplements for Skin Conditions in Healthy Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

2020 · Toshihiko Shoji, Saeko Masumoto, et al. · Nutrients · 37

PDF

Two Novel Beer-Spoilage Lactobacillus Species Isolated from Breweries

1998 · Wataru Funahashi, Koji Suzuki, et al. · Journal of the American Society of Brewing Chemists · 37

Allelic imbalance in chromosome band 18q21 andSMAD4 mutations in ovarian cancers

1999 · Satoshi Takakura, Aikou Okamoto, et al. · Genes Chromosomes and Cancer · 34

Isolation and Characterization of Glutathione Biosynthesis-deficient Mutants inSaccharomyces cerevisiae

1990 · Yasuyuki Ohtake, Atushi Satou, et al. · Agricultural and Biological Chemistry · 34

PDF

Expression of the glutathione synthetase gene of Escherichia coli B in Saccharomyces cerevisiae

1989 · Yasuyuki Ohtake, Kunihiko Watanabe, et al. · Journal of Fermentation and Bioengineering · 34

Chiral Recognition of Apple Procyanidins by Complexation with Oxotitanium Phthalocyanine

2006 · Atsuya Muranaka, Kengo Yoshida, et al. · Organic Letters · 29

Works count: 49

Citation count: 2,796

H-index: 25

I10-index: 37