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Ky‐Youb Nam

The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib
2015 · Kang-Seo Park, Bora Oh, et al. · Cancer Letters · 41
Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1
2013 · Ravichandran N. Murugan, Jung-Eun Park, et al. · Bioorganic & Medicinal Chemistry · 40
Modulation of Intracellular Calcium Levels by Calcium Lactate Affects Colon Cancer Cell Motility through Calcium-Dependent Calpain
2015 · Pasupathi Sundaramoorthy, Jae Jun Sim, et al. · PLoS ONE · 34
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De Novo Design and Synthesis of Ultra-Short Peptidomimetic Antibiotics Having Dual Antimicrobial and Anti-Inflammatory Activities
2013 · Ravichandran N. Murugan, Binu Jacob, et al. · PLoS ONE · 33
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Structure−Activity Relationship Studies of a Series of Novel δ-Lactam-Based Histone Deacetylase Inhibitors
2007 · Hwan Mook Kim, Dong-Kyu Ryu, et al. · Journal of Medicinal Chemistry · 29
Design and Synthesis of a Cell-Permeable, Drug-Like Small Molecule Inhibitor Targeting the Polo-Box Domain of Polo-Like Kinase 1
2014 · Ganipisetti Srinivasrao, Jung-Eun Park, et al. · PLoS ONE · 26
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Degradation patterns and stability predictions of the original reds and amino acid derivatives of monascus pigments
2011 · Heeyong Jung, Deokyeong Choe, et al. · European Food Research and Technology · 26
The small molecule AU14022 promotes colorectal cancer cell death via p53‐mediated G2/M‐phase arrest and mitochondria‐mediated apoptosis
2017 · Hwani Ryu, Ky‐Youb Nam, et al. · Journal of Cellular Physiology · 19
Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors
2005 · Kyeong Lee, Shanthaveerappa K. Boovanahalli, et al. · Bioorganic & Medicinal Chemistry Letters · 17
IM-412 inhibits the invasion of human breast carcinoma cells by blocking FGFR-mediated signaling
2015 · SEUNG-YOUN JUNG, JAE YOUN YI, et al. · Oncology Reports · 13
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Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor
2021 · Hwani Ryu, Ky-Youb Nam, et al. · International Journal of Molecular Sciences · 9
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Abstract 1461: PHI-101, a potent and novel inhibitor of CHK2 in ovarian and breast cancer cells
2021 · June H-J Han, Kyu-Tae Kim, et al. · Cancer Research · 9
Radiosensitizing Effect of Novel Phenylpyrimidine Derivatives on Human Lung Cancer Cells via Cell Cycle Perturbation
2019 · Seung-Youn Jung, Ky-Youb Nam, et al. · Journal of Pharmacology and Experimental Therapeutics · 8
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Identification of chalcones as potent and selective PDE5A1 inhibitors
2012 · Ky-Youb Nam, Nam Song Choi, et al. · Bioorganic & Medicinal Chemistry Letters · 6
PHI-101 Is a Potent Third-Generation FLT3 Inhibitor Developed to Overcome Resistance in Acute Myeloid Leukemia
2020 · Ky-Youb Nam, Jeejin Im, et al. · Blood · 4
Novel focal adhesion kinase 1 inhibitor sensitizes lung cancer cells to radiation in a p53-independent manner
2017 · Seung-Youn Jung, Seongho Kho, et al. · International Journal of Oncology · 4
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Discovery of a Highly Specific and Potent Pan‐ RAF Inhibitor
2016 · Sung Pyo Hong, Younho Lee, et al. · Bulletin of the Korean Chemical Society · 4
PHI-101, a Novel FLT3 TKI, Shows Clinical Efficacy in Relapsed/Refractory FLT3-Mutated AML
2024 · Dong-Yeop Shin, Sung-Soo Yoon, et al. · Blood · 3
A new cyclin-dependent kinase-9 inhibitor A09-003 induces apoptosis in acute myeloid leukemia cells with reduction of myeloid cell leukemia sequence-1 protein
2023 · Kyoung Mi Sim, So Young Kim, et al. · Chemico-Biological Interactions · 3
A Potent Small Molecule Inhibitor of FLT3, PHI-101 Overcomes Resistance in Acute Myeloid Leukemia: Efficacy and PK/PD Profile in Phase 1 First in Human Study
2022 · Sung-Soo Yoon, Dong-Yeop Shin, et al. · Blood · 3
The small molecule ‘1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate’ and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha
2016 · Mi-Na Hong, Ky-Youb Nam, et al. · Cell Stress and Chaperones · 3
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Synthesis and Biological Evaluation of Novel IM3829 (4-(2-Cyclohexylethoxy)aniline) Derivatives as Potent Radiosensitizers
2014 · Jiyeon Ahn, Ky-Youb Nam, et al. · Bulletin of the Korean Chemical Society · 3
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PHI-101 As a Potent Next-Generation FLT3 Inhibitor, Overcome Resistances in Previously Treated Patients with FLT3-ITD or TKD Acute Myeloid Leukemia: Results of a Phase Ia/Ib Clinical Trial
2023 · Sung-Soo Yoon, Dongyeop Shin, et al. · Blood · 2
Abstract 5495: PHI-501, a potent and novel inhibitor of NRAS mutated acute myeloid leukemia
2022 · Ky-Youb Nam, Jung Hee Park, et al. · Cancer Research · 1
PHI-101: a novel FLT3 inhibitor with potent activity against the F691L gatekeeper resistance mutation
2026 · Marina Mitrou, Li Li, et al. · Leukemia
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Works count: 40
Citation count: 340
H-index: 10
I10-index: 10
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