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Seung-Hwan Lee
Institutions:
University of Ottawa,
Centre for Infection, Immunity and Inflammation,
Ottawa Institute of Systems Biology
Observed institutions:
University of Ottawa,
Centre for Infection, Immunity and Inflammation,
Ottawa Institute of Systems Biology
ORCID:
0000-0001-7703-6421
Observed ORCID:
0000-0001-7703-6421
OpenAlex ID:
A5038521252
Interleukin-18 up-regulates amino acid transporters and facilitates amino acid–induced mTORC1 activation in natural killer cells
2019
·
Saeedah Musaed Almutairi
, Alaa Kassim Ali
, et al.
·
Journal of Biological Chemistry
·
69
Simultaneous engineering of natural killer cells for CAR transgenesis and CRISPR-Cas9 knockout using retroviral particles
2023
·
Dong-Hyeon Jo
, Shelby Kaczmarek
, et al.
·
Molecular Therapy — Methods & Clinical Development
·
39
Cytokines in Focus: IL-2 and IL-15 in NK Adoptive Cell Cancer Immunotherapy
2025
·
Bryan Marr
, Donghyeon Jo
, et al.
·
Immune Network
·
28
PDF
Effects of Chronic Low-Dose Internal Radiation on Immune-Stimulatory Responses in Mice
2021
·
Abrar Ul Haq Khan
, Melinda Blimkie
, et al.
·
International Journal of Molecular Sciences
·
19
PDF
Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy
2026
·
Joo-Yoon Chung
, Jisu Hong
, et al.
·
Signal Transduction and Targeted Therapy
·
5
PDF
A New Functional Screening Platform Identifies Colistin Sulfate as an Enhancer of Natural Killer Cell Cytotoxicity
2022
·
Serena Cortés-Kaplan
, Reem Kurdieh
, et al.
·
Cancers
·
4
PDF
Anti-BCMA-CAR-IL15 natural killer cells prevent multiple myeloma growth in the bone marrow but allow subsequent emergence of extramedullary disease
2025
·
Shelby Kaczmarek
, Donghyeon Jo
, et al.
·
Cancer Letters
·
2
The impact of low-dose gamma radiation on immune modulation in a mouse model of spontaneous mammary gland tumorigenesis
2025
·
Abrar Ul Haq Khan
, Melinda Blimkie
, et al.
·
Frontiers in Immunology
·
2
PDF
Nanoparticles co-delivering siRNA and mRNA for simultaneous restoration and silencing of gene/protein expression in vitro and in vivo
2024
·
Shireesha Manturthi
, Sara El-Sahli
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Current Advances and Hurdles in Chimeric Antigen Receptor Technology
2020
·
Scott McComb
, Seung-Hwan Lee
·
Cancers
·
1
PDF
AMPKα regulates glycolytic reprogramming to sustain NK cell proliferation and effector function
2026
·
Abrar Ul Haq Khan
, Jannat Pervin
, et al.
·
Cell Death and Disease
PDF
BCMA-CAR Natural Killer Cells Suppress Myeloma in Bone Marrow but Allow Emergence of Extramedullary Disease 2266680
2026
·
Seung-Hwan Lee
, Shelby Kaczmarek
, et al.
·
The Journal of Immunology
Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity
2026
·
Frederic St-Denis-Bissonnette
, Karan Mediratta
, et al.
·
Molecular Therapy Oncology
Development of Genetically Modified ARH-77 Feeder Cells for Efficient Expansion of Natural Killer Cells with Potent Anti-Tumor Activity
2026
·
Yu-Jin Lim
, Bryan Marr
, et al.
·
Cancers
PDF
BaEV-pseudotyped lentiviral vectors enable stable CAR expression and cytotoxic function in NK cells
2026
·
Minji Park
, Yuree Lim
, et al.
·
PLoS ONE
PDF
Natural Killer Cell-Derived Extracellular Vesicles Exhibit Cytotoxicity Against Bulk Tumor Cells and Cancer Stem Cells in Triple-Negative Breast Cancer
2026
·
Melanie Kirkby
, Frederic St-Denis-Bissonnette
, et al.
·
Nanomaterials
Nanobody-Based Multifunctional Killer Engagers for Next-Gen BCMA-Directed Myeloma Therapy
2025
·
Ankita Dabla
, Tina Nguyen
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
P-022 Development of trogocytosis resistant CAR-NK for multiple myeloma
2023
·
Marisa K. Kilgour
, Shelby Kaczmarek
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
Can Engineering IL-2Rα Expression Improve NK Cell Immunotherapy?
2023
·
Seung-Hwan Lee
, Bryan Marr
, et al.
·
The Journal of Immunology
PDF
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Works count:
19
Citation count:
170
H-index:
5
I10-index:
4
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