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Vigen O. Topuzyan
Observed names:
Topuzyan, V. O.,
Topuzyan, V.O.,
V O Topuzyan,
V. O Topuzyan,
V. O. TOPUZYAN,
V. O. Topuzyan,
Vigen Topuzyan
show all 7
Institutions:
A. Mnjoyan Institute of Fine Organic Chemistry,
Scientific Technological Center of Organic and Pharmaceutical Chemistry,
National Academy of Sciences of Armenia
Observed institutions:
A. Mnjoyan Institute of Fine Organic Chemistry,
Scientific Technological Center of Organic and Pharmaceutical Chemistry,
Academy of Sciences of the Soviet Union,
National Academy of Sciences of Armenia
ORCID:
0000-0002-1721-1993
Observed ORCID:
0000-0002-1721-1993
OpenAlex ID:
A5038547501
α,β-Dehydrophenylalanine choline esters, a new class of reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase
2007
·
Hasmik A. Grigoryan
, Artur A. Hambardzumyan
, et al.
·
Chemico-Biological Interactions
·
23
Design, Synthesis and Biological Evaluation of New 1, 4-Dihydropyridine (DHP) Derivatives as Selective Cyclooxygenase-2 Inhibitors.
2015
·
Iman Sabakhi
, Vigen Topuzyan
, et al.
·
PubMed Central
·
16
PDF
Synthesis and Anticholinesterase Activity of [(4Z)-2-Aryl-4-(arylmethylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]alkanoic Acids
2018
·
V. O. Topuzyan
, V. M. Kazoyan
, et al.
·
Russian Journal of Organic Chemistry
·
14
Derivatives of α,β-dehydro amino acids: I. Synthesis of 1-aryl-2,4-disubstituted imidazol-5-ones from arylamides of N-benzoyl-α,β-dehydrophenylalanine and trimethylchlorosilane
2004
·
V. O. Topuzyan
, A. A. Oganesyan
, et al.
·
Russian Journal of Organic Chemistry
·
14
Synthesis and Anticholinesterase Activity of 4-Arylidene-1-[ω-(dialkylamino)alkyl]-2-phenyl-4,5-dihydro-1(H)-imidazole-5-ones
2022
·
V. O. Topuzyan
, A. A. Hovhannisyan
, et al.
·
Russian Journal of General Chemistry
·
13
Derivatives of α,β-dehydro amino acids: III. Reaction of 4-arylmethylidene-4,5-dihydro-1,3-oxazol-5-ones with hexamethyldisilazane
2007
·
V. O. Topuzyan
, L. G. Arutyunyan
, et al.
·
Russian Journal of Organic Chemistry
·
11
Derivatives of α,β-dehydro amino acids: II. New synthesis of 2,4-disubstituted 1-aminoimidazol-5-ones from N-substituted α,β-unsaturated α-amino acid hydrazides
2007
·
V. O. Topuzyan
, L. G. Arutyunyan
, et al.
·
Russian Journal of Organic Chemistry
·
9
Design, synthesis and biological evaluation of 5-oxo-1,4,5,6,7,8 hexahydroquinoline derivatives as selective cyclooxygenase-2 inhibitors.
2014
·
Afshin Zarghi
, Iman Sabakhi
, et al.
·
PubMed Central
·
8
PDF
Derivatives of α,β-dehydroamino acids: V. Intramolecular cyclization of 2-{2-[(Z)-1-Benzamido-2-phenylvinyl]acetamidomethyl}benzimidazole
2009
·
V. O. Topuzyan
, M. M. Kazandzhyan
, et al.
·
Russian Journal of Organic Chemistry
·
7
Unnatural Phosphorus‐Containing α‐Amino Acids and Their N‐FMOC Derivatives: Synthesis and In Vitro Investigation of Anticholinesterase Activity
2024
·
Ani S. Dadayan
, Anna F. Mkrtchyan
, et al.
·
ChemistrySelect
·
6
PDF
Synthesis and Some Pharmacological Properties of N-Benzoyl-α,β-dehydrotyrosine-Containing Dipeptides
2022
·
V. O. Topuzyan
, A. A. Hovhannisyan
, et al.
·
Russian Journal of General Chemistry
·
6
Derivatives of α,β-dehydro amino acids. Synthesis of 2-aryl-4-arylmethylidene-1-arylmethylideneamino-4,5-dihydro-1H-imidazol-5-ones by reaction of N-substituted α,β-dehydro amino acid arylmethylidenehydrazides with hexamethyldisilazane
2008
·
V. O. Topuzyan
, L. G. Arutyunyan
, et al.
·
Russian Journal of Organic Chemistry
·
6
Synthesis, Anticholinesterase, and Antiradical Activity of 2,3,5-Trisubstituted 4Н-Imidazol-4-ones, Green Fluorescent Protein Chromophore Analogues
2023
·
V. O. Topuzyan
, S. R. Tosunyan
, et al.
·
Russian Journal of General Chemistry
·
5
Methods of Synthesis and Properties of β-Dimethylaminoethyl and Choline Esters of Aminoacids and Peptides
1981
·
O L Mndzhoyan
, V O Topuzyan
·
Russian Chemical Reviews
·
5
New S- And N- Substituted Derivatives Of 5-Aryloxymethyl-1,2,4-Triazoles And Their Biological Activity
2022
·
S. V. Dilanyan
, T. R. Hovsepyan
, et al.
·
Chemical Journal of Armenia
·
4
PDF
Application of the Benzoyl O-Protecting Group in the Synthesis of α,β-Dehydrotyrosine-containing Amides and Imidazolones
2022
·
V. O. Topuzyan
, A. A. Hovhannisyan
, et al.
·
Russian Journal of Organic Chemistry
·
4
Synthesis and Biological Activity of (Z)-Dialkylaminoalkylamides of N-Benzoyl-α,β-Dehydroamino Acids and Their Iodomethylates
2018
·
V. O. Topuzyan
, S. R. Tosunyan
, et al.
·
Pharmaceutical Chemistry Journal
·
3
Synthesis and Anticholinesterase Properties of Choline esters of α-Amino Acids
2014
·
V. O. Topuzyan
, I. R. Karapetyan
, et al.
·
Pharmaceutical Chemistry Journal
·
3
Synthesis and anticholinesterase activity of 2-(dimethylamino)ethyl and choline esters of n-substituted α, β-dehydroamino acids
2006
·
A. A. Grigoryan
, A. A. Ambartsumyan
, et al.
·
Pharmaceutical Chemistry Journal
·
3
Choline esters of N-subtituted amino acids. VIII. Synthesis and neurotropic properties of β-dimentylaminoethyl ester salts of N-(p-alkoxybenzoyl)-α,β-dehydrophenylalanines
1997
·
V. O. Topuzyan
, A. S. Nesunts
, et al.
·
Pharmaceutical Chemistry Journal
·
3
Synthesis and biological properties of N-substituted α,β-dehydrodipeptides
1995
·
V. O. Topuzyan
, A. Z. Akopyan
, et al.
·
Pharmaceutical Chemistry Journal
·
3
Synthesis, Antiradical and Anticholinesterase Аctivity of Kетоamides of N-Substituted α,β-Dehydroamino Acids and Corresponding Imidazol-4-ones
2024
·
A. G. Agababyan
, N. A. Hovhannisyan
, et al.
·
Russian Journal of General Chemistry
·
2
A New Method for the Synthesis of 2,3-Aryl-5-arylideneimidazol-4-ones Using N-Trimethylsilylimidazole
2023
·
V. O. Topuzyan
, S. R. Tosunyan
, et al.
·
Russian Journal of General Chemistry
·
2
Synthesis of Silicon Dioxide Xerogels and Their Sorption–Desorption Properties with Respect to Nicotine and Glycols
2023
·
S. G. Grigoryan
, E. H. Hakopyan
, et al.
·
Russian Journal of General Chemistry
·
2
Study of neuroprotective activity of new acetylcholinesterase inhibitors TVA and TVS in experimental model of Alzheimer’s disease
2022
·
Hrachik V. Gasparyan
, Sona A. Buloyan
, et al.
·
Research Results in Pharmacology
·
2
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Works count:
83
Citation count:
201
H-index:
8
I10-index:
6
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