Get started
Author

Jaime Mella

Observed names: J. Mella, J. Mella-Raipan, J. Mella‐Raipán, JAIME MELLA-RAIPÁN, Jaime Mella-Raipán, Jaime Mella-Raipán, Jaime Mella‐Raipán, Mella, Jaime
ORCID: 0000-0002-2434-8461
Observed ORCID: 0000-0002-2434-8461
OpenAlex ID: A5039270117
Design, synthesis, antifungal activity, and structure–activity relationship studies of chalcones and hybrid dihydrochromane–chalcones
2019 · Marco Mellado, Luis Espinoza, et al. · Molecular Diversity · 71
Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors
2021 · Marco Mellado, César González, et al. · Bioorganic Chemistry · 39
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
2016 · Javier Romero-Parra, Jaime Mella-Raipán, et al. · European Journal of Medicinal Chemistry · 39
Antioxidant Capacity of Pure Compounds and Complex Mixtures Evaluated by the ORAC-Pyrogallol Red Assay in the Presence of Triton X-100 Micelles
2010 · Max Romero, Benjamin Rojano, et al. · Molecules · 39
PDF
Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line: Quantitative Structure–Activity Relationship Models
2018 · Marco Mellado, Alejandro Madrid, et al. · Medicinal Chemistry Research · 37
Design, Synthesis, and Molecular Modeling Studies of a Novel Benzimidazole as an Aromatase Inhibitor
2022 · Ulviye Acar Çevik, Ismail Celik, et al. · ACS Omega · 36
PDF
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease
2020 · Julio Rodríguez-Lavado, Carlos Gallardo-Garrido, et al. · European Journal of Medicinal Chemistry · 34
Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays
2019 · Cristian O. Salas, Ana Maria Zarate, et al. · International Journal of Molecular Sciences · 34
PDF
Novel Classes of Antibacterial Drugs in Clinical Development, a Hope in a Post-antibiotic Era
2018 · J. Campanini-Salinas, J. Andrades-Lagos, et al. · Current Topics in Medicinal Chemistry · 32
State of the Art of Smo Antagonists for Cancer Therapy: Advances in the Target Receptor and New Ligand Structures
2019 · Christian Espinosa-Bustos, Jaime Mella, et al. · Future Medicinal Chemistry · 30
Hansch’s analysis application to chalcone synthesis by Claisen–Schmidt reaction based in DFT methodology
2017 · Marco Mellado, Alejandro Madrid, et al. · Chemical Papers · 30
New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia
2019 · Jeanluc Bertrand, Hana Dostálová, et al. · Bioorganic Chemistry · 29
Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles
2018 · Marcos Lorca, Cesar Morales-Verdejo, et al. · Molecules · 27
PDF
Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
2017 · Javier Romero-Parra, Hery Chung, et al. · European Journal of Pharmaceutical Sciences · 24
Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands
2013 · Jaime Mella-Raipán, Carlos Lagos, et al. · Molecules · 23
PDF
3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
2020 · Marco Mellado, Jaime Mella, et al. · Bioorganic Chemistry · 20
Evaluation of the Membrane Permeability (PAMPA and Skin) of Benzimidazoles with Potential Cannabinoid Activity and their Relation with the Biopharmaceutics Classification System (BCS)
2011 · M. Javiera Alvarez-Figueroa, C. David Pessoa-Mahana, et al. · AAPS PharmSciTech · 20
Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
2022 · Marco Mellado, César González, et al. · Molecules · 19
PDF
DARK Classics in Chemical Neuroscience: Heroin and Desomorphine
2020 · Jaime Mella-Raipán, Javier Romero-Parra, et al. · ACS Chemical Neuroscience · 18
3D-QSAR/CoMFA-Based Structure-Affinity/Selectivity Relationships of Aminoalkylindoles in the Cannabinoid CB1 and CB2 Receptors
2014 · Jaime Mella-Raipán, Santiago Hernández-Pino, et al. · Molecules · 18
PDF
Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands
2019 · Marcos Lorca, Yudisladys Valdes, et al. · International Journal of Molecular Sciences · 16
PDF
2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β3-Adrenergic Activity
2017 · Gastón Apablaza, Luisa Montoya, et al. · Molecules · 16
PDF
Microwave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo[1,2d][1,4]benzodiazepinone derivatives
2009 · David Pessoa-Mahana, Christian Espinosa-Bustos, et al. · ARKIVOC · 16
PDF
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia
2022 · Jeanluc Bertrand, Hana Dostálová, et al. · Pharmaceutics · 15
PDF
Extended N-Arylsulfonylindoles as 5-HT6 Receptor Antagonists: Design, Synthesis & Biological Evaluation
2016 · Gonzalo Vera, Carlos Lagos, et al. · Molecules · 14
PDF
Works count: 75
Citation count: 918
H-index: 18
I10-index: 31
Year
Topic
Type