Get started
Author

Lynsey R. Chatham

Observed names: Chatham, L. R., L. R. Chatham, L.R. Chatham, Lynsey Chatham
Observed institutions: Queen's University Belfast, University of Dundee, Cancer Research UK, Innovative Medicines Initiative, Ninewells Hospital, Concept Life Sciences (United Kingdom)
OpenAlex ID: A5039707670
Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines
2012 · Nico Scheer, Yury Kapelyukh, et al. · Molecular Pharmacology · 54
Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes
2018 · Corinne Haines, Barbara M. Elcombe, et al. · Toxicology · 30
Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats
2018 · Corinne Haines, Lynsey R. Chatham, et al. · Xenobiotica · 24
Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance
2020 · Brian G. Lake, Roger J. Price, et al. · Toxicology · 14
Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance
2019 · Christiane Wiemann, Manuela Goettel, et al. · Toxicology · 14
An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity
2019 · Roger J. Price, Rachel Burch, et al. · Xenobiotica · 12
Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats
2018 · Corinne Haines, Lynsey R. Chatham, et al. · Toxicology · 12
A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity
2017 · R. Sumanth Iyer, Lynsey Chatham, et al. · Scientific Reports · 11
PDF
Evidence That the Capacity of Nongenotoxic Carcinogens to Induce Oxidative Stress Is Subject to Marked Variability
2015 · Colin J. Henderson, Amy R. Cameron, et al. · Toxicological Sciences · 7
PDF
Mode of action analysis for fluxapyroxad-induced rat liver tumour formation: evidence for activation of the constitutive androstane receptor and assessment of human relevance
2024 · Manuela Goettel, Christoph Werner, et al. · Toxicology · 6
Comparative studies on the effects of sodium phenobarbital and two other constitutive androstane receptor (CAR) activators on induction of cytochrome P450 enzymes and replicative DNA synthesis in cultured hepatocytes from wild type and CAR knockout rats
2020 · Manuela Goettel, Ivana Fegert, et al. · Toxicology · 6
The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
2025 · C. J. Henderson, A. W. McLaren, et al. · Archives of Toxicology · 3
Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats
2020 · Larry G. Higgins, Lynsey R. Chatham, et al. · Toxicology · 3
Correction: The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
2026 · C. J. Henderson, A. W. McLaren, et al. · Archives of Toxicology
PDF
In vitro approaches to risk assess chemical mediated changes in thyroid function
2018 · L.G. Higgins, C. Haines, et al. · Toxicology Letters
Distinct Chromosomal Alterations Segregate with SEPT6 Expression Levels in Leukaemia
2012 · Chatham, L. R., Todd, C. B., et al. · Research Portal (Queen's University Belfast)
Abstract 244: Effects of upregulation of Sept6 v4** splice variant in AML
2010 · Ekaterina Minskaia, Lynsey Chatham, et al. · Cancer Research
Works count: 17
Citation count: 196
H-index: 8
I10-index: 8
Year
Topic
Type