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Jan G. Felber

Observed names: Felber, Jan, Felber, Jan G., Jan Felber, Jan G Felber
Institution: Tubulis (Germany)
ORCID: 0000-0002-5010-9624
Observed ORCID: 0000-0002-5010-9624
OpenAlex ID: A5040084945
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2
2023 · Yongfeng Tao, Jan G. Felber, et al. · Angewandte Chemie International Edition · 72
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Selective cellular probes for mammalian thioredoxin reductase TrxR1: Rational design of RX1, a modular 1,2-thiaselenane redox probe
2022 · Lukas Zeisel, Jan G. Felber, et al. · Chem · 52
Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif
2021 · Jan G. Felber, Lukas Zeisel, et al. · Journal of the American Chemical Society · 51
Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically
2022 · Jan Felber, Lena Poczka, et al. · Nature Communications · 44
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40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs
2022 · Jan G. Felber, Oliver Thorn-Seshold · JACS Au · 33
Cyclic Dichalcogenides Extend the Reach of Bioreductive Prodrugs to Harness Thiol/Disulfide Oxidoreductases: Applications to seco -Duocarmycins Targeting the Thioredoxin System
2023 · Jan G. Felber, Annabel Kitowski, et al. · ACS Central Science · 26
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Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology
2024 · Lukas Zeisel, Jan G. Felber, et al. · Journal of the American Chemical Society · 23
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Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates
2026 · Philipp Ochtrop, Anil P. Jagtap, et al. · Nature Communications · 9
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Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines – a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline
2018 · Benedikt C Melzer, Jan G Felber, et al. · Beilstein Journal of Organic Chemistry · 5
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Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2
2023 · Yongfeng Tao, Jan G. Felber, et al. · Angewandte Chemie · 1
Abstract 7018: Antibody-degrader conjugates unlock the therapeutic potential of heterobifunctional degraders through antibody-like pharmacokinetics and excellent in vivo efficacy
2025 · Jan G. Felber, Anil P. Jagtap, et al. · Cancer Research
Krebsmedikamente zum Anschalten
2024 · Jan G. Felber · Nachrichten aus der Chemie
CCDC 2214471: Experimental Crystal Structure Determination
2023 · Felber, Jan G., Kitowski, Annabel, et al. · The Cambridge Structural Database
Correction to “40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs”
2023 · Jan G. Felber, Oliver Thorn-Seshold · JACS Au
Development of a chemical probe that selectively images the activity of mammalian Thioredoxin Reductase 1
2022 · Lukas Zeisel, Jan Felber, et al. · Free Radical Biology and Medicine
CCDC 2072439: Experimental Crystal Structure Determination
2021 · Felber, Jan G., Zeisel, Lukas, et al. · The Cambridge Structural Database
CCDC 2072440: Experimental Crystal Structure Determination
2021 · Felber, Jan G., Zeisel, Lukas, et al. · The Cambridge Structural Database
CCDC 2072441: Experimental Crystal Structure Determination
2021 · Felber, Jan G., Zeisel, Lukas, et al. · The Cambridge Structural Database
CCDC 2072442: Experimental Crystal Structure Determination
2021 · Felber, Jan G., Zeisel, Lukas, et al. · The Cambridge Structural Database
CCDC 2072438: Experimental Crystal Structure Determination
2021 · Felber, Jan G., Zeisel, Lukas, et al. · The Cambridge Structural Database
Cyclic 5-Membered Disulfides Are Not Selective Substrates of Thioredoxin Reductase, but Are Opened Nonspecifically by Thiols
2020 · Jan Felber, Lena Poczka, et al. · ChemRxiv
Works count: 25
Citation count: 316
H-index: 8
I10-index: 7
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