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Shizhen Qiu

Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness
2023 · Jian Chen, Shizhen Qiu, et al. · Cell Research · 195
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Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy
2020 · Wentao Li, Shizhen Qiu, et al. · Immunity · 160
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NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
2021 · Yuetong Wang, Fei Wang, et al. · Cell Reports · 123
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CAR-Toner: an AI-driven approach for CAR tonic signaling prediction and optimization
2024 · Shizhen Qiu, Jian Chen, et al. · Cell Research · 80
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Design of diversified chimeric antigen receptors through rational module recombination
2023 · Wen Si, Ying-Ying Fan, et al. · iScience · 12
Potentiating the anti-tumor response of tumor infiltrated T cells by NAD + supplementation
2020 · Yuetong Wang, Fei Wang, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
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All-in-one Hangzhou Protocol: killing four birds with one stone
2024 · Haopeng Wang, Shizhen Qiu, et al. · Cell Research · 2
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Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma (Adv. Sci. 35/2026)
2026 · Xiang Xu, Shizhen Qiu, et al. · Advanced Science · 1
Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma
2026 · Xiang Xu, Shizhen Qiu, et al. · Advanced Science · 1
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NAD+ Supplement Potentiates Tumor Killing Function by Rescuing Defective Tubby-Mediated NAMPT Transcription in Tumor Infiltrated T Cells
2021 · Yuetong Wang, Fei Wang, et al. · SSRN Electronic Journal · 1
PD-L1 transmembrane domain substitution overcomes CAR-T exhaustion driven by tonic signaling
2026 · Liang Zhang, Xiang Xu, et al. · Molecular Therapy Oncology
Author Correction: Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness
2026 · Jian Chen, Shizhen Qiu, et al. · Cell Research
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Lineage Plasticity–Mediated Resistance to CD7-Directed CAR-T Therapy in Relapsed/Refractory T-ALL/LBL
2026 · Jiahua Niu, Kun Wang, et al. · Transplantation and Cellular Therapy
Targeting pulmonary fibrosis with DDR2-specific chimeric antigen receptor macrophages
2026 · Jin Su, Yunxin Lai, et al. · Research Square
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A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis
2025 · Xu Chen, Yunxin Lai, et al. · medRxiv
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A core epitope targeting antibody of SARS-CoV-2
2022 · Simeng Zhao, Fengjiang Liu, et al. · Protein & Cell
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Works count: 16
Citation count: 580
H-index: 5
I10-index: 5
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