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Wojciech Pietruś
Observed names:
Pietruś, Wojciech,
W. Pietruś,
Wojciech Pietruś
Institutions:
Celon Pharma (Poland),
Maj Institute of Pharmacology,
Polish Academy of Sciences
Observed institutions:
Jagiellonian University,
University of Bonn,
Akademia Tarnowska,
Celon Pharma (Poland),
Maj Institute of Pharmacology,
Polish Academy of Sciences
show all 6
ORCID:
0000-0002-8563-7929
Observed ORCID:
0000-0002-8563-7929
OpenAlex ID:
A5040233819
Works
55
Awards
1
Hydrogen Bonds with Fluorine in Ligand–Protein Complexes-the PDB Analysis and Energy Calculations
2022
·
Wojciech Pietruś
, Rafał Kafel
, et al.
·
Molecules
·
57
PDF
Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity
2019
·
Katarzyna Grychowska
, Severine Chaumont-Dubel
, et al.
·
ACS Chemical Neuroscience
·
39
Tuning the activity of known drugs via the introduction of halogen atoms, a case study of SERT ligands – Fluoxetine and fluvoxamine
2021
·
Jakub Staroń
, Wojciech Pietruś
, et al.
·
European Journal of Medicinal Chemistry
·
32
Dual Piperidine-Based Histamine H 3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
2023
·
Katarzyna Szczepańska
, Tadeusz Karcz
, et al.
·
Journal of Medicinal Chemistry
·
26
PDF
Imidazopyridine-Based 5-HT6 Receptor Neutral Antagonists: Impact of N1-Benzyl and N1-Phenylsulfonyl Fragments on Different Receptor Conformational States
2021
·
David Vanda
, Vittorio Canale
, et al.
·
Journal of Medicinal Chemistry
·
23
2-Aminoimidazole-based antagonists of the 5-HT6 receptor – A new concept in aminergic GPCR ligand design
2019
·
Adam S. Hogendorf
, Agata Hogendorf
, et al.
·
European Journal of Medicinal Chemistry
·
23
From NMR to AI: Designing a Novel Chemical Representation to Enhance Machine Learning Predictions of Physicochemical Properties
2024
·
Arkadiusz Leniak
, Wojciech Pietruś
, et al.
·
Journal of Chemical Information and Modeling
·
20
Overcoming undesirable hERG affinity by incorporating fluorine atoms: A case of MAO-B inhibitors derived from 1 H-pyrrolo-[3,2-c]quinolines
2022
·
Katarzyna Grychowska
, Agnieszka Olejarz-Maciej
, et al.
·
European Journal of Medicinal Chemistry
·
19
PDF
How can fluorine directly and indirectly affect the hydrogen bonding in molecular systems? – A case study for monofluoroanilines
2021
·
Wojciech Pietruś
, Rafał Kurczab
, et al.
·
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
·
19
Superiority of the Triple-Acting 5-HT6R/5-HT3R Antagonist and MAO-B Reversible Inhibitor PZ-1922 over 5-HT6R Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats
2023
·
Katarzyna Grychowska
, Uriel López-Sánchez
, et al.
·
Journal of Medicinal Chemistry
·
15
PDF
Alkaloid from Colchicum species in complexes with lithium, sodium, potassium and magnesium cations– spectroscopic characterization, semiempirical and theoretical calculation, fungicidal and cytotoxic activity
2019
·
Joanna Kurek
, Patrycja Kwaśniewska-Sip
, et al.
·
Journal of Molecular Structure
·
13
From NMR to AI: Do We Need 1 H NMR Experimental Spectra to Obtain High-Quality logD Prediction Models?
2025
·
Arkadiusz Leniak
, Wojciech Pietruś
, et al.
·
Journal of Chemical Information and Modeling
·
11
Design, Synthesis, and Development of Pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part II—Benzimidazole Derivatives
2022
·
Mariola Stypik
, Stanisław Michałek
, et al.
·
Pharmaceuticals
·
11
PDF
Influence of Fluorine Substitution on Nonbonding Interactions in Selected Para‐Halogeno Anilines
2021
·
Wojciech Pietruś
, Rafał Kurczab
, et al.
·
ChemPhysChem
·
10
Isomeric Activity Cliffs—A Case Study for Fluorine Substitution of Aminergic G Protein-Coupled Receptor Ligands
2023
·
Wojciech Pietruś
, Rafał Kurczab
, et al.
·
Molecules
·
9
PDF
Histamine H3 receptor blockade alleviates neuropathic pain through the regulation of glial cells activation
2025
·
Maciej Degutis
, Dorota Łażewska
, et al.
·
Biomedicine & Pharmacotherapy
·
8
Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer
2024
·
Delfina Popiel
, Aleksandra Stańczak
, et al.
·
Frontiers in Oncology
·
7
Role of Staple Molecules in the Formation of S···S Contact in Thioamides: Experimental Charge Density and Theoretical Studies
2019
·
Agata Owczarzak
, Zbigniew Dutkiewicz
, et al.
·
Crystal Growth & Design
·
6
Unlocking the potential of higher-molecular-weight 5-HT7R ligands: Synthesis, affinity, and ADMET examination
2024
·
Patryk Pyka
, Sabrina Garbo
, et al.
·
Bioorganic Chemistry
·
5
5-HT6 receptor neutral antagonists protect astrocytes: A lesson from 2-phenylpyrrole derivatives
2024
·
Marcin Drop
, Paulina Koczurkiewicz-Adamczyk
, et al.
·
European Journal of Medicinal Chemistry
·
5
PDF
Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT6 and D3R Affinity in the 1H-Pyrrolo[3,2-c]quinoline Series
2023
·
Katarzyna Grychowska
, Wojciech Pietruś
, et al.
·
Molecules
·
5
From NMR to AI: Fusing 1H and 13C Representations for Enhanced QSPR Modeling
2025
·
Arkadiusz Leniak
, Wojciech Pietruś
, et al.
·
Journal of Chemical Information and Modeling
·
4
PDF
Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors
2021
·
Wojciech Pietruś
, Rafał Kurczab
, et al.
·
Biomolecules
·
4
PDF
Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT6R ligands binding mode
2020
·
Jakub Staroń
, Ryszard Bugno
, et al.
·
European Journal of Medicinal Chemistry
·
3
Identification of pyrrolo[2,3-d]pyrimidine-based dual MERTK and FLT3 inhibitor: Hit-to-lead, machine learning, modeling, synthesis, and biological evaluation
2026
·
Abdellah Yamani
, Paweł Maliszewski
, et al.
·
European Journal of Pharmaceutical Sciences
·
2
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Works count:
55
Citation count:
379
H-index:
11
I10-index:
14
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