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Dorothy C.C. Wai

Observed names: D.C. Wai, D.C.C. Wai, Dorothy C. C. Wai, Dorothy C. Wai, Dorothy Wai, Dorothy C.C. Wai, Wai, D. C.C., Wai, Dorothy C. C., Wai, Dorothy C.C.
Institution: Monash University
ORCID: 0000-0002-3871-9980
Observed ORCID: 0000-0002-3871-9980
OpenAlex ID: A5040310260
A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence
2018 · Bin Lu, Olaf Klingbeil, et al. · Cancer Cell · 69
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The voltage-gated potassium channel KV1.3 as a therapeutic target for venom-derived peptides
2020 · Gabor Tajti, Dorothy C.C. Wai, et al. · Biochemical Pharmacology · 63
The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators
2018 · Dorothy C.C. Wai, Taylor N. Szyszka, et al. · Journal of Biological Chemistry · 63
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The zinc fingers of YY1 bind single-stranded RNA with low sequence specificity
2016 · Dorothy C.C. Wai, Manar Shihab, et al. · Nucleic Acids Research · 38
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Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone
2021 · Michela L. Mitchell, Mohammed Akhter Hossain, et al. · Biomolecules · 20
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Blockade of Microglial Kv1.3 Potassium Channels by the Peptide HsTX1[R14A] Attenuates Lipopolysaccharide-mediated Neuroinflammation
2021 · Joseph A. Nicolazzo, Yijun Pan, et al. · Journal of Pharmaceutical Sciences · 19
A disulfide-stabilised helical hairpin fold in acrorhagin I: An emerging structural motif in peptide toxins
2020 · Bankala Krishnarjuna, Punnepalli Sunanda, et al. · Journal of Structural Biology · 19
Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family
2023 · Lauren M. Ashwood, Khaled A. Elnahriry, et al. · BMC Biology · 18
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Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa
2019 · Khaled A. Elnahriry, Dorothy C.C. Wai, et al. · Toxicon · 18
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Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice
2023 · Yijun Pan, Yoshiteru Kagawa, et al. · Neurotherapeutics · 12
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A Biodistribution Study of the Radiolabeled Kv1.3-Blocking Peptide DOTA-HsTX1[R14A] Demonstrates Brain Uptake in a Mouse Model of Neuroinflammation
2022 · Sanjeevini Babu Reddiar, Michael de Veer, et al. · Molecular Pharmaceutics · 12
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Lipopolysaccharide influences the plasma and brain pharmacokinetics of subcutaneously-administered HsTX1[R14A], a KV1.3-blocking peptide
2021 · Sanjeevini Babu Reddiar, Liang Jin, et al. · Toxicon · 12
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Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni
2023 · Khaled A. Elnahriry, Dorothy C.C. Wai, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 11
Conformational exchange in the potassium channel blocker ShK
2019 · Naoto Iwakawa, Nicola J. Baxter, et al. · Scientific Reports · 10
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Conformational dynamics in peptide toxins: Implications for receptor interactions and molecular design
2021 · Karoline Sanches, Dorothy C.C. Wai, et al. · Toxicon · 8
A Fluorescent Peptide Toxin for Selective Visualization of the Voltage-Gated Potassium Channel KV1.3
2022 · Dorothy C. C. Wai, Muhammad Umair Naseem, et al. · Bioconjugate Chemistry · 7
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Fragment-based and structure-guided discovery of perforin inhibitors
2023 · Jiney Jose, Ruby H.P. Law, et al. · European Journal of Medicinal Chemistry · 6
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Structure–function relationships in ShKT domain peptides: ShKT‐Ts1 from the sea anemone Telmatactis stephensoni
2023 · Karoline Sanches, Lauren M. Ashwood, et al. · Proteins Structure Function and Bioinformatics · 5
Structure and functional studies of Avt1, a novel peptide from the sea anemone Aulactinia veratra
2024 · Renad A. Albar, Hayden L. Smith, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 4
Inhibition of KV1.3-KV1.x heterotetramers by KV1.3-specific inhibitory peptides
2024 · Muhammad Umair Naseem, Amna S. Al Olaimi, et al. · Biophysical Journal · 1
Genomic, Functional and Structural Analyses Reveal Mechanisms of Evolutionary Innovation within the Sea Anemone 8 Toxin Family
2022 · Lauren M. Ashwood, Khaled A. Elnahriry, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Lipidation of the KV1.3 blocking peptide HsTX1[R14A] alters its pharmacokinetics and biodistribution
2026 · Lihuan Lin, Thomas R. Mitchell, et al. · International Journal of Pharmaceutics
Brain Delivery of a Kv1.3-Blocking Peptide is not Enhanced by Conjugation to Blood–Brain Barrier Shuttle Peptides
2026 · Dorothy C. C. Wai, Liam M. Koehn, et al. · International Journal of Peptide Research and Therapeutics
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Cell-penetrant peptides as novel inhibitors of the interaction of coatomer protein COPB2/RACK2 with protein kinase Cε and cargo proteins
2025 · Abisola A. Olushola-Siedoks, Lewin Small, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Kv1.3 Inhibition Alleviates Diabetic Kidney Injury via Suppression of Inflammation and Fibrosis
2025 · Yuting Zhang, Ji Bian, et al. · Journal of the American Society of Nephrology
Works count: 52
Citation count: 416
H-index: 12
I10-index: 14
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