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Hequn Li

A Next-Generation Risk Assessment Case Study for Coumarin in Cosmetic Products
2020 · Maria T Baltazar, Sophie Cable, et al. · Toxicological Sciences · 162
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Intestinal absorption, metabolism, and excretion of (–)-epicatechin in healthy humans assessed by using an intestinal perfusion technique
2013 · Lucas Actis-Goretta, Antoine Lévèques, et al. · American Journal of Clinical Nutrition · 114
Assessment of an in vitro transport model using BeWo b30 cells to predict placental transfer of compounds
2013 · Hequn Li, Bennard van Ravenzwaay, et al. · Archives of Toxicology · 101
Are Non-animal Systemic Safety Assessments Protective? A Toolbox and Workflow
2022 · Alistair M Middleton, Joe Reynolds, et al. · Toxicological Sciences · 81
Identifying and Characterizing Stress Pathways of Concern for Consumer Safety in Next-Generation Risk Assessment
2020 · Sarah Hatherell, Maria T Baltazar, et al. · Toxicological Sciences · 65
Application of physiologically based kinetic (PBK) modelling in the next generation risk assessment of dermally applied consumer products
2019 · Thomas E. Moxon, Hequn Li, et al. · Toxicology in Vitro · 61
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Comparison and preliminary discussion of the reasons for the differences in diagnostic performance and unnecessary FNA biopsies between the ACR TIRADS and 2015 ATA guidelines
2019 · Xiao-Li Wu, Jia-Rui Du, et al. · Endocrine · 55
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment
2022 · Abdulkarim Najjar, Ans Punt, et al. · Archives of Toxicology · 53
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Use of physiologically based kinetic modeling-facilitated reverse dosimetry of in vitro toxicity data for prediction of in vivo developmental toxicity of tebuconazole in rats
2016 · Hequn Li, Mengying Zhang, et al. · Toxicology Letters · 51
The diagnostic accuracy of liver fibrosis in non-viral liver diseases using acoustic radiation force impulse elastography: A systematic review and meta-analysis
2020 · Yuanqiang Lin, Hequn Li, et al. · PLoS ONE · 49
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Beyond AOPs: A Mechanistic Evaluation of NAMs in DART Testing
2022 · Ramya Rajagopal, Maria T. Baltazar, et al. · Frontiers in Toxicology · 48
Risk assessment in the 21st century: where are we heading?
2022 · Susy Brescia, Camilla Alexander-White, et al. · Toxicology Research · 39
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Next generation risk assessment (NGRA): Bridging in vitro points-of-departure to human safety assessment using physiologically-based kinetic (PBK) modelling – A case study of doxorubicin with dose metrics considerations
2021 · Hequn Li, Haitao Yuan, et al. · Toxicology in Vitro · 30
Extended evaluation on the ES-D3 cell differentiation assay combined with the BeWo transport model, to predict relative developmental toxicity of triazole compounds
2015 · Hequn Li, Burkhard Flick, et al. · Archives of Toxicology · 23
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PBK modelling of topical application and characterisation of the uncertainty of Cmax estimate: A case study approach
2022 · Hequn Li, Joe Reynolds, et al. · Toxicology and Applied Pharmacology · 22
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Integrating in vitro testing and physiologically-based pharmacokinetic (PBPK) modelling for chemical liver toxicity assessment—A case study of troglitazone
2019 · Lin Yu, Hequn Li, et al. · Environmental Toxicology and Pharmacology · 21
Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
2014 · Belén Sanchez-Bridge, Antoine Lévèques, et al. · Drug Metabolism and Disposition · 21
Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application
2022 · Abdulkarim Najjar, Andreas Schepky, et al. · Frontiers in Pharmacology · 18
Employing Dietary Comparators to Perform Risk Assessments for Anti-Androgens Without Using Animal Data
2018 · Matthew P Dent, Hequn Li, et al. · Toxicological Sciences · 16
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Using Intuitionistic Fuzzy Set for Anomaly Detection of Network Traffic From Flow Interaction
2018 · Jinfa Wang, Hai Zhao, et al. · IEEE Access · 16
Next generation risk assessment of human exposure to anti-androgens using newly defined comparator compound values
2021 · Tessa C.A. van Tongeren, Thomas E. Moxon, et al. · Toxicology in Vitro · 11
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Cascade-penetrating domino-ferroptosis nano inducer synergizes with sonodynamic therapy for anaplastic thyroid cancer
2025 · Peng Dong, Yun-Bo Chi, et al. · Materials Today Bio · 10
ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application
2023 · Hequn Li, Fazila Bunglawala, et al. · Toxicological Sciences · 10
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Making safety decisions for a sunscreen active ingredient using next-generation risk assessment: Benzophenone-4 case study
2025 · Maria T. Baltazar, Sophie Cable, et al. · ALTEX · 9
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Exploration of key pathogenic mechanisms and potential intervention targets of the traditional Chinese medicine Coptis chinensis in the treatment of cervical cancer based on network pharmacology and molecular docking techniques
2025 · Ying Hou, Lei Zhang, et al. · Translational Cancer Research · 8
Works count: 39
Citation count: 1,129
H-index: 18
I10-index: 23
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