Author

Shaymaa Emam Kassab

Observed names: Kassab, Shaymaa E., Shaymaa E. Kassab, Shaymaa Emam Kassaba, Shaymaa Kassab

Observed institutions: University of Maryland, Baltimore, Cairo University, Damanhour University, University of Sadat City, King Salman International University, Misr International University

ORCID: 0000-0002-4789-2662

Observed ORCID: 0000-0002-4789-2662

OpenAlex ID: A5040479819

Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma

2023 · Ahmed I. Khodair, Salwa M. El-Hallouty, et al. · European Journal of Medicinal Chemistry · 58

Design, synthesis, biological evaluation and docking studies of new 3-(4,5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15-lipoxygenase inhibitors

2018 · Haydi Saher ElBordiny, Mostafa Mahmoud El-Miligy, et al. · European Journal of Medicinal Chemistry · 54

Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents

2014 · Mona M. Abdel-Atty, Nahla A. Farag, et al. · Bioorganic Chemistry · 40

Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities

2017 · Shaymaa E. Kassab, Mohammed A. Khedr, et al. · European Journal of Medicinal Chemistry · 38

Design, synthesis and biological evaluation of novel thiohydantoin derivatives as antiproliferative agents: A combined experimental and theoretical assessments

2021 · Mostafa M. Elbadawi, Ahmed I. Khodair, et al. · Journal of Molecular Structure · 33

A Promising Anti-Cancer and Anti-Oxidant Agents Based on the Pyrrole and Fused Pyrrole: Synthesis, Docking Studies and Biological Evaluation

2015 · Samar Fatahala, Emad Shalaby, et al. · Anti-Cancer Agents in Medicinal Chemistry · 29

Base-catalyzed one-step synthesis of 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines

2015 · Xinhua He, Shaymaa E. Kassab, et al. · Tetrahedron Letters · 26

Synthesis of 1H-Indole-2,3-Dione-3-Thiosemicarbazone Ribonucleosides as Antibacterial Agents

2009 · Shaymaa E. Kassab, Gehan H. Hegazy, et al. · Nucleosides Nucleotides & Nucleic Acids · 24

Synthesis of novel d-α-galactopyranosyl-l-seryl/l-threonyl-l-alanyl-l-alanine as useful precursors of new glycopeptide antibiotics with computational calculations studies

2022 · Ahmed I. Khodair, Shaymaa E. Kassab, et al. · Carbohydrate Research · 21

Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and in silico ADMET studies

2021 · Aya Y. Rashad, Shaymaa E. Kassab, et al. · Bioorganic Chemistry · 20

AI-DPAPT: a machine learning framework for predicting PROTAC activity

2024 · Amr S. Abouzied, Bahaa Alshammari, et al. · Molecular Diversity · 18

Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma

2019 · Shaymaa E. Kassab, Samar Mowafy, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 16

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Treatment of non-small cell lung cancer using chem-bioinformatics-driven engineering of exosomal cargo-vehicle for telmisartan and pioglitazone targeted-delivery

2025 · Nadia M. Hamdy, Eman F. Sanad, et al. · Scientific Reports · 15

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Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity

2021 · Mahmoud A. Ragab, Mohamed Elagawany, et al. · Bioorganic Chemistry · 13

Rational Design and Synthesis of New Selective COX-2 Inhibitors with In Vivo PGE2-Lowering Activity by Tethering Benzenesulfonamide and 1,2,3-Triazole Pharmacophores to Some NSAIDs

2022 · Nada H. El-Dershaby, Soad A. El-Hawash, et al. · Pharmaceuticals · 12

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Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme

2022 · Nada H. El-Dershaby, Soad A. El-Hawash, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 9

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Indomethacin from Anti-Inflammatory to Anticancer Agent

2019 · Shaymaa Emam Kassab · IntechOpen eBooks · 6

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Structural Basis of Selective Human Indoleamine‐2,3‐dioxygenase 1 (hIDO1) Inhibition

2021 · Shaymaa Emam Kassab, Samar Mowafy · ChemMedChem · 5

Synthesis of New 9-glycosyl-4,9-dihydropyrano [3,4-b]indole-1(3H)-ones as Antibacterial Agents

2011 · Shaymaa E. Kassab, Gehan H. Hegazy, et al. · Nucleosides Nucleotides & Nucleic Acids · 4

A new computational cross-structure-activity relationship (C-SAR) approach applies to a selective HDAC6 inhibitor dataset for accelerated structure development

2025 · Shaymaa E. Kassab · Computers in Biology and Medicine · 2

Precise structure manipulation of selective estrogen receptor modulators led to first-in-class thiophene-3-benzamide derivatives as potential ER-antagonists without uterotrophic activity

2025 · Bader Huwaimel, Amr S. Abouzied, et al. · Bioorganic Chemistry · 1

Corrigendum to “A new computational cross-structure-activity relationship (C-SAR) approach applies to a selective HDAC6 inhibitor dataset for accelerated structure development” [Comput. Biol. Med. 192 (2025) 110169]

2025 · Shaymaa E. Kassab · Computers in Biology and Medicine

Future Perspectives of Indomethacin from being anti-Inflammatory to being anticancerAgent

2020 · Shaymaa Emam Kassaba · Journal of Chemical Biology & Pharmaceutical Chemistry

ChemInform Abstract: Base‐Catalyzed One‐Step Synthesis of 5,7‐Disubstituted‐1,2,4‐triazolo[1,5‐a]pyrimidines.

2015 · Xinhua He, Shaymaa E. Kassab, et al. · ChemInform

ChemInform Abstract: Synthesis of New 9‐Glycosyl‐4,9‐dihydropyrano[3,4‐b]indole‐1(3H)‐ones as Antibacterial Agents.

2012 · Shaymaa E. Kassab, Gehan H. Hegazy, et al. · ChemInform

Works count: 28

Citation count: 444

H-index: 13

I10-index: 15