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David G. Tew

Observed names: D G Tew, D Tew, D. G. TEW, D. G. Tew, D. TEW, D. Tew, D.G. Tew, DAVID G. TEW, David G Tew, David G. TEW, David TEW, David Tew, David G. Tew
Observed institutions: University of Eastern Finland, University of Dundee, University of California, San Francisco, GlaxoSmithKline (United Kingdom), Quadram Institute, University of Oxford, GlaxoSmithKline (United States), GlaxoSmithKline Research & Development Limited (United Kingdom)
ORCID: 0000-0002-9328-1248
Observed ORCID: 0000-0002-9328-1248
OpenAlex ID: A5040491538
Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
1999 · Ishrut Hussain, David Powell, et al. · Molecular and Cellular Neuroscience · 1,110
Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase
1993 · V B O'Donnell, D G Tew, et al. · Biochemical Journal · 595
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Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor
1999 · Colin H. MACPHEE, Kitty E. MOORES, et al. · Biochemical Journal · 361
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Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions
1999 · Tomi Häkkinen, Jukka S. Luoma, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 239
4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo
2005 · Lara S. Kallander, Qing Lu, et al. · Journal of Medicinal Chemistry · 191
The myoglobin protein radical. Coupling of Tyr-103 to Tyr-151 in the H2O2-mediated cross-linking of sperm whale myoglobin.
1988 · D Tew, P R Ortiz de Montellano · Journal of Biological Chemistry · 182
ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site
2000 · I. Hussain, D.J. Powell, et al. · Molecular and Cellular Neuroscience · 166
Purification, Properties, Sequencing, and Cloning of a Lipoprotein-Associated, Serine-Dependent Phospholipase Involved in the Oxidative Modification of Low-Density Lipoproteins
1996 · David G. Tew, Christopher Southan, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 163
The role of ATP citrate-lyase in the metabolic regulation of plasma lipids
1998 · Nigel J. PEARCE, John W. YATES, et al. · Biochemical Journal · 152
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Dissection of NADPH-cytochrome P450 oxidoreductase into distinct functional domains.
1994 · G C Smith, D G Tew, et al. · Proceedings of the National Academy of Sciences · 137
Nitric oxide synthases catalyze the activation of redox cycling and bioreductive anticancer agents.
1999 · A P Garner, M J Paine, et al. · PubMed · 110
Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases
2002 · David J. Payne, Juan Antonio Hueso-Rodríguez, et al. · Antimicrobial Agents and Chemotherapy · 109
Inhibition of cytochrome P450 reductase by the diphenyliodonium cation. Kinetic analysis and covalent modifications
1993 · David G. Tew · Biochemistry · 106
Azepanone-Based Inhibitors of Human and Rat Cathepsin K
2001 · Robert W. Marquis, Yu Ru, et al. · Journal of Medicinal Chemistry · 103
Cloning and Characterization of a Novel Human Dual Flavin Reductase
2000 · Mark J.I. Paine, Andrew P. Garner, et al. · Journal of Biological Chemistry · 85
Napsins: new human aspartic proteinases
1998 · Peter J Tatnell, David J Powell, et al. · FEBS Letters · 84
Crystal structure of the FMN‐binding domain of human cytochrome P450 reductase at 1.93 Å resolution
1999 · Qiang Zhao, Sandeep Modi, et al. · Protein Science · 83
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Inhibition of herpes proteases and antiviral activity of 2-substituted thieno[2,3-d]oxazinones
1999 · Richard L. Jarvest, Ivan L. Pinto, et al. · Bioorganic & Medicinal Chemistry Letters · 80
Improved betulinic acid biosynthesis using synthetic yeast chromosome recombination and semi-automated rapid LC-MS screening
2020 · G.-O. F. Gowers, S. M. Chee, et al. · Nature Communications · 78
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Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore
2007 · Joseph P. Marino,, Paul W. Fisher, et al. · Journal of Medicinal Chemistry · 77
A versatile biosynthetic approach to amide bond formation
2018 · Helena K. Philpott, Pamela J. Thomas, et al. · Green Chemistry · 75
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Steady-State Kinetic Characterization of Substrates and Metal-Ion Specificities of the Full-Length and N-Terminally Truncated Recombinant Human Methionine Aminopeptidases (Type 2)
2001 · Guang Yang, Robert B. Kirkpatrick, et al. · Biochemistry · 74
Decorating Self-Assembled Peptide Cages with Proteins
2017 · James F. Ross, Angela Bridges, et al. · ACS Nano · 63
Nitrogen-15 NMR studies of nitrosyl (bent and linear), nitro, and nitrito ligands in 4-, 5-, and 6-coordinate complexes of the platinum metals
1983 · Linda K. Bell, Joan Mason, et al. · Inorganic Chemistry · 60
Cyclic Ketone Inhibitors of the Cysteine Protease Cathepsin K
2001 · Robert W. Marquis, Yu Ru, et al. · Journal of Medicinal Chemistry · 52
Works count: 72
Citation count: 5,340
H-index: 34
I10-index: 52
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