Author

Yanhe Wen

Institutions: Massachusetts Eye and Ear Infirmary, Harvard University

Observed institutions: Massachusetts Eye and Ear Infirmary, Boston Children's Hospital, Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Boston Children's Cancer and Blood Disorders Center

ORCID: 0000-0003-3536-6056

Observed ORCID: 0000-0003-3536-6056

OpenAlex ID: A5040628306

MEN1 mutations mediate clinical resistance to menin inhibition

2023 · Florian Perner, Eytan M. Stein, et al. · Nature · 251

The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML

2021 · Emily B. Heikamp, Jill A. Henrich, et al. · Blood · 152

Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2022 · Hannah J. Uckelmann, Elena L. Haarer, et al. · Cancer Discovery · 134

Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML

2023 · Wallace Bourgeois, Jevon A. Cutler, et al. · Blood · 30

NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AML

2024 · Emily B. Heikamp, Cynthia Martucci, et al. · Cell Reports · 17

S125: Non-genetic Resistance to Menin Inhibition in Aml Is Reversible by Perturbation of Kat6a

2023 · Florian Perner, Homa Rahnamoun, et al. · HemaSphere · 13

Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer

2025 · Sarah Naomi Olsen, Bryn Anderson, et al. · Cell Reports Medicine · 12

p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma

2025 · Laura C Godfrey, Brandon Regalado, et al. · EMBO Reports · 8

The KMT2A-PTD oncoprotein depends on ENL but not menin to drive AML gene expression

2025 · Daniela Wenge, Maria Wessels, et al. · Blood · 1

Functional evaluation of a natural AAV capsid liver targeting motif in human hepatocytes

2026 · Carmen Unzu, Amanda X. Chen, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Supplementary Tables S1-S14 from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2025 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Supplementary Figures S1-S12 from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2025 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Data from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2023 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Data from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2023 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Supplementary Figures S1-S12 from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2023 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Supplementary Tables S1-S14 from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2023 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Supplementary Tables S1-S14 from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2023 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Supplementary Figures S1-S12 from Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2023 · Hannah J. Uckelmann, Elena L. Haarer, et al.

Mutant NPM1 Is Recruited to MLL Target Genes Via Its Acidic Stretch and Nuclear Export Factor CRM1 and Regulates Oncogenic Transcription in Acute Myeloid Leukemia

2022 · Hannah J Uckelmann, Elena L Haarer, et al. · Blood

Works count: 19

Citation count: 618

H-index: 8

I10-index: 7