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Diego Angosto-Bazarra

Observed names: Angosto-Bazarra, Diego, Diego Angosto, Diego Angosto‐Bazarra
ORCID: 0000-0001-5990-4678
Observed ORCID: 0000-0001-5990-4678
OpenAlex ID: A5040972911
MCC950 closes the active conformation of NLRP3 to an inactive state
2019 · Ana Tapia-Abellán, Diego Angosto-Bazarra, et al. · Nature Chemical Biology · 462
Cell Volume Regulation Modulates NLRP3 Inflammasome Activation
2012 · Vincent Compan, Alberto Baroja-Mazo, et al. · Immunity · 411
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P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis
2019 · Juan José Martínez-García, Helios Martínez-Banaclocha, et al. · Nature Communications · 252
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Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017 · Mattia Cocco, Carolina Pellegrini, et al. · Journal of Medicinal Chemistry · 176
Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation
2021 · Ana Tapia-Abellán, Diego Angosto-Bazarra, et al. · Science Advances · 159
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
2018 · Iva Hafner-Bratkovič, Petra Sušjan, et al. · Nature Communications · 151
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Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
2016 · Sylwia D. Tyrkalska, Sergio Candel, et al. · Nature Communications · 129
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Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β
2012 · Diego Angosto, Gloria López-Castejón, et al. · Innate Immunity · 91
RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly
2020 · Yanhui Duan, Lingzhi Zhang, et al. · Cell Reports · 90
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Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality
2022 · Diego Angosto-Bazarra, Cristina Alarcón-Vila, et al. · BMC Biology · 87
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NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers
2022 · Laura Hurtado-Navarro, Diego Angosto-Bazarra, et al. · Antioxidants · 50
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Gasdermin D mediates a fast transient release of ATP after NLRP3 inflammasome activation before ninjurin 1-induced lytic cell death
2025 · Julieta Schachter, Adriana Guijarro, et al. · Cell Reports · 43
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production
2024 · Cristina Molina-López, Laura Hurtado-Navarro, et al. · Nature Communications · 41
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A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish
2014 · Francisca Alcaraz-Pérez, Jesús García-Castillo, et al. · Nature Communications · 41
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Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles
2022 · Diego Angosto-Bazarra, Cristina Molina-López, et al. · Communications Biology · 38
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Amniotic membrane stimulates cell migration by modulating transforming growth factor‐β signalling
2017 · Catalina Ruiz‐Cañada, Ángel Bernabé‐García, et al. · Journal of Tissue Engineering and Regenerative Medicine · 38
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Soluble P2X7 Receptor Is Elevated in the Plasma of COVID-19 Patients and Correlates With Disease Severity
2022 · Julio García-Villalba, Laura Hurtado-Navarro, et al. · Frontiers in Immunology · 37
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TLR agonists extend the functional lifespan of professional phagocytic granulocytes in the bony fish gilthead seabream and direct precursor differentiation towards the production of granulocytes
2011 · María P. Sepulcre, Azucena López-Muñoz, et al. · Molecular Immunology · 34
Characterization of Novel Pathogenic Variants Leading to Caspase-8 Cleavage-Resistant RIPK1-Induced Autoinflammatory Syndrome
2022 · Alfonso José Tapiz i Reula, Alexis-Virgil Cochino, et al. · Journal of Clinical Immunology · 23
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Identification and functional characterization of a new IL-1 family member, IL-1Fm2, in most evolutionarily advanced fish
2013 · Diego Angosto, Jana Montero, et al. · Innate Immunity · 21
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Techniques to Study Inflammasome Activation and Inhibition by Small Molecules
2021 · Diego Angosto-Bazarra, Cristina Molina-López, et al. · Molecules · 19
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The zebrafish as a model to study the inflammasome
2014 · Diego Angosto, Victoriano Mulero · Inflammasome · 14
Addendum: MCC950 closes the active conformation of NLRP3 to an inactive state
2021 · Ana Tapia-Abellán, Diego Angosto-Bazarra, et al. · Nature Chemical Biology · 13
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Aluminum is a powerful adjuvant in teleost fish despite failing to induce interleukin-1β release
2018 · Diego Angosto, Azucena López-Muñoz, et al. · Developmental & Comparative Immunology · 12
Evolution of the gasdermin family and pyroptosis
2023 · Diego Angosto-Bazarra, Adriana Guijarro, et al. · Developmental & Comparative Immunology · 11
Works count: 42
Citation count: 2,451
H-index: 20
I10-index: 25
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