Author

Matthew A. J. Duncton

Observed names: Duncton, M., Duncton, Matthew, Duncton, Matthew A. J., M. DUNCTON, M. Duncton, M.A.J Duncton, Matthew A J Duncton, Matthew A.J. Duncton, Matthew A. J. Duncton, Matthew Duncton

Observed institutions: University of Nottingham, Loughborough University, University of Canterbury, University of Florida, MSD (UK) Limited (United Kingdom), Rigel (United States), Accelero Biostructures, Vernalis (R&D) Limited (United Kingdom), Evotec (United States)

ORCID: 0000-0002-6007-7515

Observed ORCID: 0000-0002-6007-7515

OpenAlex ID: A5041051375

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

2011 · Matthew A. J. Duncton · MedChemComm · 618

Identification and characterization of novel TRPV4 modulators

2009 · Fabien Vincent, Alejandra Acevedo, et al. · Biochemical and Biophysical Research Communications · 251

TRPV4 Agonists and Antagonists

2011 · Fabien Vincent, Matthew A.J. Duncton · Current Topics in Medicinal Chemistry · 158

The intramolecular Stille reaction

1999 · Matthew A. J. Duncton, Gerald Pattenden · Journal of the Chemical Society Perkin Transactions 1 · 152

Preparation of Heteroaryloxetanes and Heteroarylazetidines by Use of a Minisci Reaction

2009 · Matthew A. J. Duncton, M. Angels Estiarte, et al. · The Journal of Organic Chemistry · 103

Preparation of Aryloxetanes and Arylazetidines by Use of an Alkyl−Aryl Suzuki Coupling

2008 · Matthew A. J. Duncton, M. Angels Estiarte, et al. · Organic Letters · 78

4-Substituted-3-phenylquinolin-2(1H)-ones: Acidic and Nonacidic Glycine SiteN-Methyl- d -aspartate Antagonists withinVivoActivity

1997 · Robert W. Carling, Paul D. Leeson, et al. · Journal of Medicinal Chemistry · 69

Synthesis of trans-2-(Trifluoromethyl)cyclopropanes via Suzuki Reactions with an N-Methyliminodiacetic Acid Boronate

2013 · Matthew A. J. Duncton, Rajinder Singh · Organic Letters · 65

Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor

2009 · Jeff DeFalco, Daniel Steiger, et al. · Bioorganic & Medicinal Chemistry Letters · 61

Arylphthalazines: Identification of a new phthalazine chemotype as inhibitors of VEGFR kinase

2005 · Evgueni L. Piatnitski, Matthew A.J. Duncton, et al. · Bioorganic & Medicinal Chemistry Letters · 55

Orally Absorbed Derivatives of the β-Lactamase Inhibitor Avibactam. Design of Novel Prodrugs of Sulfate Containing Drugs

2018 · Eric M. Gordon, Matthew A. J. Duncton, et al. · Journal of Medicinal Chemistry · 52

Indoline derivatives as 5-HT 2C receptor agonists

2004 · J.M Bentley, D.R Adams, et al. · Bioorganic & Medicinal Chemistry Letters · 45

Identification of orally-bioavailable antagonists of the TRPV4 ion-channel

2015 · Zhi-Liang Wei, Margaret T. Nguyen, et al. · Bioorganic & Medicinal Chemistry Letters · 44

Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2

2008 · Matthew A.J. Duncton, Eugene L. Piatnitski Chekler, et al. · Bioorganic & Medicinal Chemistry · 38

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

2020 · David M. Wilson, Ashley M. Deacon, et al. · Progress in Biophysics and Molecular Biology · 37

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Stereoselective synthesis of the indolizinoindole ring system

2003 · Steven M. Allin, Christopher I. Thomas, et al. · Tetrahedron Letters · 36

Dibutyl 2-(trifluoromethyl)cyclopropylboronate as a useful (trifluoromethyl)cyclopropyl donor: application to antagonists of TRPV1

2009 · Matthew A.J. Duncton, Leticia Ayala, et al. · Tetrahedron Letters · 35

Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase

2006 · Leon Smith, Wai C. Wong, et al. · Bioorganic & Medicinal Chemistry Letters · 35

Arylphthalazines. Part 2: 1-(Isoquinolin-5-yl)-4-arylamino phthalazines as potent inhibitors of VEGF receptors I and II

2005 · Matthew A.J. Duncton, Evgueni L. Piatnitski, et al. · Bioorganic & Medicinal Chemistry Letters · 35

Preparation of Substituted Pyrimido[4,5-b]-1,4-benzoxazepines, Thiazepines, and Diazepines via a Pictet−Spengler Cyclization

2005 · Matthew A. J. Duncton, Leon M. Smith, et al. · The Journal of Organic Chemistry · 32

TRPM8 Biology and Medicinal Chemistry

2011 · Jeff DeFalco, Matthew A.J. Duncton, et al. · Current Topics in Medicinal Chemistry · 30

Preparation of 6-chloro-5-fluoroindole via the use of palladium and copper-mediated heterocyclisations

2002 · David R. Adams, Matthew A.J. Duncton, et al. · Tetrahedron Letters · 30

5-Benzyloxytryptamine as an antagonist of TRPM8

2010 · Jeff DeFalco, Daniel Steiger, et al. · Bioorganic & Medicinal Chemistry Letters · 25

Tetrazolone as an acid bioisostere: application to marketed drugs containing a carboxylic acid

2016 · Matthew A. J. Duncton, Ryan B. Murray, et al. · Organic & Biomolecular Chemistry · 22

Parallel synthesis of N-arylpiperazines using polymer-assisted reactions

2006 · Matthew A.J. Duncton, Jonathan R.A. Roffey, et al. · Tetrahedron Letters · 22

Works count: 79

Citation count: 2,351

H-index: 23

I10-index: 35