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Roberto De Luca

Observed names: De Luca, R, De Luca, R., De Luca, Roberto, R De Luca, R Luca, R. De Luca
ORCID: 0000-0001-7519-8689
Observed ORCID: 0000-0001-7519-8689
OpenAlex ID: A5041586621
Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold
2018 · Yizhou Li, Roberto De Luca, et al. · Nature Chemistry · 133
Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications
2021 · Nicholas Favalli, Gabriele Bassi, et al. · Nature Chemistry · 72
Potency-matched Dual Cytokine–Antibody Fusion Proteins for Cancer Therapy
2017 · Roberto De Luca, Alex Soltermann, et al. · Molecular Cancer Therapeutics · 48
Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library
2022 · Sara Puglioli, Eleonore Schmidt, et al. · Chem · 47
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell–dependent regression of glioblastoma
2023 · Thomas Look, Emanuele Puca, et al. · Science Translational Medicine · 46
A novel anti-cancer L19-interleukin-12 fusion protein with an optimized peptide linker efficiently localizes in vivo at the site of tumors
2018 · Tiziano Ongaro, Mattia Matasci, et al. · Journal of Biotechnology · 39
A Comparative Analysis of Fibroblast Activation Protein-Targeted Small Molecule–Drug, Antibody–Drug, and Peptide–Drug Conjugates
2023 · Aureliano Zana, Claudia Puig-Moreno, et al. · Bioconjugate Chemistry · 35
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody
2022 · Lisa Nadal, Frederik Peissert, et al. · Journal for ImmunoTherapy of Cancer · 31
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Potentiation of PD-L1 blockade with a potency-matched dual cytokine–antibody fusion protein leads to cancer eradication in BALB/c-derived tumors but not in other mouse strains
2018 · Roberto De Luca, Dario Neri · Cancer Immunology Immunotherapy · 28
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Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells
2024 · Laura Volta, Renier Myburgh, et al. · Leukemia · 25
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A Novel Antibody–IL15 Fusion Protein Selectively Localizes to Tumors, Synergizes with TNF-based Immunocytokine, and Inhibits Metastasis
2021 · Riccardo Corbellari, Marco Stringhini, et al. · Molecular Cancer Therapeutics · 22
The immunocytokine L19-TNF eradicates sarcomas in combination with chemotherapy agents or with immune check-point inhibitors
2020 · Riccardo Corbellari, Lisa Nadal, et al. · Anti-Cancer Drugs · 19
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Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo
2020 · Lisa Nadal, Riccardo Corbellari, et al. · mAbs · 18
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A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Carcinomas
2019 · Roberto De Luca, Baptiste Gouyou, et al. · Frontiers in Oncology · 18
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Tumor-Homing Antibody-Cytokine Fusions for Cancer Therapy
2024 · Eleonora Prodi, Dario Neri, et al. · OncoTargets and Therapy · 16
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A novel dual-cytokine–antibody fusion protein for the treatment of CD38-positive malignancies
2018 · Roberto De Luca, Paul Kachel, et al. · Protein Engineering Design and Selection · 15
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Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice
2025 · Carmine Carbone, Roberto De Luca, et al. · Journal of Experimental & Clinical Cancer Research · 12
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Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen
2023 · Louis Plüss, Frederik Peissert, et al. · mAbs · 11
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Selection of a PD ‐1 blocking antibody from a novel fully human phage display library
2022 · Frederik Peissert, Louis Plüss, et al. · Protein Science · 11
Optimizing the Design and Geometry of T Cell–Engaging Bispecific Antibodies Targeting CEA in Colorectal Cancer
2024 · Abdullah Elsayed, Louis Plüss, et al. · Molecular Cancer Therapeutics · 10
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A novel strategy to generate immunocytokines with activity-on-demand using small molecule inhibitors
2024 · Giulia Rotta, Ettore Gilardoni, et al. · EMBO Molecular Medicine · 10
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An IL-7 fusion protein targeting EDA fibronectin upregulates TCF1 on CD8+ T-cells, preferentially accumulates to neoplastic lesions, and boosts PD-1 blockade
2024 · Cesare Di Nitto, Domenico Ravazza, et al. · Journal for ImmunoTherapy of Cancer · 9
Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties
2023 · Abdullah Elsayed, Christian Pellegrino, et al. · mAbs · 9
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DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target
2024 · Laura Lucaroni, Sebastian Oehler, et al. · Chemical Science · 8
Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology
2023 · Frederik Peissert, Mattia Pedotti, et al. · Global Challenges · 8
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Works count: 105
Citation count: 751
H-index: 15
I10-index: 21
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