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Shin Kwak

RNA editing and death of motor neurons
2004 · Yukio Kawahara, Kyoko Ito, et al. · Nature · 557
Calcium-permeable AMPA channels in neurodegenerative disease and ischemia
2006 · Shin Kwak, John H Weiss · Current Opinion in Neurobiology · 262
Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis
2004 · Shin Kwak, Yukio Kawahara · Journal of Molecular Medicine · 221
Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis
1999 · Hiroshi Takuma, Shin Kwak, et al. · Annals of Neurology · 213
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons
2011 · Takuto Hideyama, Takenari Yamashita, et al. · Neurobiology of Disease · 200
A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology
2012 · Takenari Yamashita, Takuto Hideyama, et al. · Nature Communications · 184
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Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2
2010 · Takuto Hideyama, Takenari Yamashita, et al. · Journal of Neuroscience · 162
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Human spinal motoneurons express low relative abundance of GluR2 mRNA: an implication for excitotoxicity in ALS
2003 · Yukio Kawahara, Shin Kwak, et al. · Journal of Neurochemistry · 134
TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2
2010 · Hitoshi Aizawa, Jun Sawada, et al. · Acta Neuropathologica · 119
Correspondence
1997 · S Nagao, S Kwak, et al. · Neuroscience · 116
The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients
2013 · Takenari Yamashita, Shin Kwak · Brain Research · 91
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AMPA receptor-mediated neuronal death in sporadic ALS
2010 · Shin Kwak, Takuto Hideyama, et al. · Neuropathology · 87
The AMPA receptor antagonist perampanel robustly rescues amyotrophic lateral sclerosis (ALS) pathology in sporadic ALS model mice
2016 · Megumi Akamatsu, Takenari Yamashita, et al. · Scientific Reports · 75
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Low editing efficiency of GluR2 mRNA is associated with a low relative abundance of ADAR2 mRNA in white matter of normal human brain
2003 · Yukio Kawahara, Kyoko Ito, et al. · European Journal of Neuroscience · 74
Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9‐ADAR2 delivery to motor neurons
2013 · Takenari Yamashita, Hui Lin Chai, et al. · EMBO Molecular Medicine · 66
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Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA
2005 · Yukio Kawahara, Hui Sun, et al. · Neuroscience Research · 63
Excitotoxicity and ALS: What is unique about the AMPA receptors expressed on spinal motor neurons?
2005 · Yukio Kawahara, Shin Kwak · Amyotrophic Lateral Sclerosis · 60
High‐affinity Na+/K+‐dependent glutamate transporter EAAT4 is expressed throughout the rat fore‐ and midbrain
2008 · Ann Massie, Lieselotte Cnops, et al. · The Journal of Comparative Neurology · 56
Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptor‐mediated excitotoxicity in ALS
2006 · Hui Sun, Yukio Kawahara, et al. · Journal of Neurochemistry · 51
Extracellular RNAs as Biomarkers of Sporadic Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases
2019 · Takashi Hosaka, Takenari Yamashita, et al. · International Journal of Molecular Sciences · 50
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Determination of editors at the novel A-to-I editing positions
2008 · Yoshinori Nishimoto, Takenari Yamashita, et al. · Neuroscience Research · 50
Late-onset selective neuronal damage in the rat spinal cord induced by continuous intrathecal administration of AMPA
1994 · Ryohji Nakamura, Keiko Kamakura, et al. · Brain Research · 46
When Does ALS Start? ADAR2?GluA2 Hypothesis for the Etiology of Sporadic ALS
2011 · Takuto Hideyama, Shin Kwak · Frontiers in Molecular Neuroscience · 44
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Studies on neurotransmitter markers and neuronal cell density in the cerebellar system in olivopontocerebellar atrophy and cortical cerebellar atrophy
1985 · Ichiro Kanazawa, Shin Kwak, et al. · Journal of the Neurological Sciences · 43
Deficient RNA-editing enzyme ADAR2 in an amyotrophic lateral sclerosis patient with a FUSP525L mutation
2016 · Hitoshi Aizawa, Takuto Hideyama, et al. · Journal of Clinical Neuroscience · 42
Works count: 84
Citation count: 3,865
H-index: 31
I10-index: 55
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