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Lars‐Oliver Tykocinski

Observed names: L TYKOCINSKI, L Tykocinski, L. Tykocinski, L.-O. Tykocinski, Lars Tykocinski, Lars-Oliver Tykocinski, Lars-Olivier Tykocinski
ORCID: 0000-0002-7645-1559
Observed ORCID: 0000-0002-7645-1559
OpenAlex ID: A5041724167
Third-generation CD19.CAR-T cell-containing combination therapy in Scl70+ systemic sclerosis
2023 · Wolfgang Merkt, Merle Freitag, et al. · Annals of the Rheumatic Diseases · 130
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Expression of IL‐10 in Th memory lymphocytes is conditional on IL‐12 or IL‐4, unless the IL‐10 gene is imprinted by GATA‐3
2007 · Hyun‐Dong Chang, Christina Helbig, et al. · European Journal of Immunology · 106
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Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis
2020 · M. Margarida Souto‐Carneiro, Karel D. Klika, et al. · Arthritis & Rheumatology · 101
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Association of an SNP with intrathymic transcription of TSHR and Graves' disease: a role for defective thymic tolerance
2011 · Roger Colobran, Maria del Pilar Armengol, et al. · Human Molecular Genetics · 81
Distinct human circulating NKp30 + FcεRIγ + CD8 + T cell population exhibiting high natural killer-like antitumor potential
2018 · Margareta P. Correia, Ana Stojanovic, et al. · Proceedings of the National Academy of Sciences · 70
A Critical Control Element for Interleukin-4 Memory Expression in T Helper Lymphocytes
2005 · Lars-Oliver Tykocinski, Petra Hajkova, et al. · Journal of Biological Chemistry · 70
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Effect of JAK Inhibition on the Induction of Proinflammatory HLA – DR + CD90 + Rheumatoid Arthritis Synovial Fibroblasts by Interferon‐γ
2021 · Shuyang Zhao, Ricardo Grieshaber‐Bouyer, et al. · Arthritis & Rheumatology · 69
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Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells
2010 · Lars-Oliver Tykocinski, Anna Sinemus, et al. · Proceedings of the National Academy of Sciences · 53
Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
2021 · Peter Kvacskay, Nina Yao, et al. · Arthritis Research & Therapy · 52
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An evolutionarily conserved mutual interdependence between A ire and micro RNA s in promiscuous gene expression
2013 · Olga Ucar, Lars‐Oliver Tykocinski, et al. · European Journal of Immunology · 52
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IL-10 Is Excluded from the Functional Cytokine Memory of Human CD4+ Memory T Lymphocytes
2007 · Jun Dong, Claudia Ivascu, et al. · The Journal of Immunology · 51
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Extracellular vesicles mediate intercellular communication: Transfer of functionally active microRNAs by microvesicles into phagocytes
2017 · Laura Claßen, Lars‐Oliver Tykocinski, et al. · European Journal of Immunology · 46
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The Thymus Medulla Slowly Yields Its Secrets
2008 · Lars‐Oliver Tykocinski, Anna Sinemus, et al. · Annals of the New York Academy of Sciences · 46
Activated human B cells induce inflammatory fibroblasts with cartilage-destructive properties and become functionally suppressed in return
2015 · Hannah Störch, Birgit Zimmermann, et al. · Annals of the Rheumatic Diseases · 43
Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma
2019 · Soumya R. Mohapatra, Ahmed Sadik, et al. · Frontiers in Immunology · 40
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Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism
2017 · Lars-Oliver Tykocinski, Anna M Lauffer, et al. · The Journal of Immunology · 39
Apoptotic cell-derived membrane microparticles and IFN-α induce an inflammatory immune response
2015 · A. Niessen, P. Heyder, et al. · Journal of Cell Science · 39
Microvesicles released by apoptotic human neutrophils suppress proliferation and IL‐2/IL‐2 receptor expression of resting T helper cells
2017 · Guifen Shen, Stefan Krienke, et al. · European Journal of Immunology · 33
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DNA methylation signatures of the AIRE promoter in thymic epithelial cells, thymomas and normal tissues
2011 · Vivian Kont, Astrid Murumägi, et al. · Molecular Immunology · 33
Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism
2019 · Nathalie-Christin Kaul, Soumya R Mohapatra, et al. · Lara D. Veeken · 24
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts
2026 · Wolfgang Merkt, Lea Rodon, et al. · Science Translational Medicine · 4
Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes
2021 · Nina Yao, Theresa Tretter, et al. · Biomedicines · 4
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Enrichment of Immune Cell‐Derived Extracellular Vesicles From Plasma Using 35 and 70 nm Size‐Exclusion Chromatography Columns of Different Sizes
2025 · Iris Potakowskyj, Ivan Bagarić, et al. · Journal of Extracellular Biology · 3
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Blood biomarker fingerprints in a cohort of patients with CHRNE-related congenital myasthenic syndrome
2025 · Adela Della Marina, Andrie Koutsoulidou, et al. · Acta Neuropathologica Communications · 1
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A GATA-3 binding site in the first intron of the interleukin-4 gene defines a critical element for the memory expression of interleukin-4 in Th lymphocytes
2003 · L Tykocinski, P Hajkova, et al. · Arthritis Research · 1
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Works count: 37
Citation count: 1,191
H-index: 20
I10-index: 20
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