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Jessica K. Holien

Observed names: Holien, Jessica, Holien, Jessica K, J. Holien, J.K. Holien, Jessica Holien, Jessica Holien (18033589), Jessica Holien K, Jessica K Holien, Jessica Kate Holien, Jessica K Holien, Jessica K. Holien
Observed institutions: Beth Israel Deaconess Medical Center, Harvard University, Baker Heart and Diabetes Institute, Emory University, The University of Melbourne, Australian Cancer Research Foundation, St Vincent's Hospital Melbourne, Weill Cornell Medicine, St Vincents Institute of Medical Research, RMIT University
ORCID: 0000-0002-8735-2871
Observed ORCID: 0000-0002-8735-2871
OpenAlex ID: A5041778642
A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development
2014 · Martina Sanderson-Smith, David M. P. De Oliveira, et al. · The Journal of Infectious Diseases · 317
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Oncogenic protein interfaces: small molecules, big challenges
2014 · Tracy L. Nero, Craig J. Morton, et al. · Nature reviews. Cancer · 312
Improvements, trends, and new ideas in molecular docking: 2012–2013 in review
2015 · Elizabeth Yuriev, Jessica Holien, et al. · Journal of Molecular Recognition · 264
Zanamivir-Resistant Influenza Viruses with a Novel Neuraminidase Mutation
2009 · Aeron C. Hurt, Jessica K. Holien, et al. · Journal of Virology · 233
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
2015 · Ueli Nachbur, Che A. Stafford, et al. · Nature Communications · 149
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Oseltamivir Resistance and the H274Y Neuraminidase Mutation in Seasonal, Pandemic and Highly Pathogenic Influenza Viruses
2009 · Aeron C. Hurt, Jessica K. Holien, et al. · Drugs · 125
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Mitochondrial fission – a drug target for cytoprotection or cytodestruction?
2016 · Ayeshah A. Rosdah, Jessica K. Holien, et al. · Pharmacology Research & Perspectives · 123
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TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members
2012 · Jessica L. Bell, Alena Malyukova, et al. · PLoS ONE · 118
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In Vitro Generation of Neuraminidase Inhibitor Resistance in A(H5N1) Influenza Viruses
2009 · Aeron C. Hurt, Jessica K. Holien, et al. · Antimicrobial Agents and Chemotherapy · 115
Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers
2011 · Anthony L Albiston, Shanti Diwakarla, et al. · British Journal of Pharmacology · 87
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Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster
2021 · Trent Perry, Wei Chen, et al. · Insect Biochemistry and Molecular Biology · 78
New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology
2020 · Ayeshah A. Rosdah, William J. Smiles, et al. · Pharmacology & Therapeutics · 77
Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor
2013 · Nima Etemadi, Jessica K. Holien, et al. · FEBS Journal · 73
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Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission
2020 · Siavash Beikoghli Kalkhoran, Janos Kriston-Vizi, et al. · Cardiovascular Research · 67
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Crystal structure of human insulin‐regulated aminopeptidase with specificity for cyclic peptides
2014 · Stefan J. Hermans, David B. Ascher, et al. · Protein Science · 66
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A novel small molecule inhibitor of human Drp1
2022 · Ayeshah A. Rosdah, Belinda M. Abbott, et al. · Scientific Reports · 61
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A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
2020 · Bishnu P Paudel, Aaron Lavel Moye, et al. · eLife · 55
Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity
2012 · Susanne C. Feil, Sara Lawrence, et al. · Structure · 51
Synthesis, Structure–Activity Relationships and Brain Uptake of a Novel Series of Benzopyran Inhibitors of Insulin-Regulated Aminopeptidase
2014 · Simon J. Mountford, Anthony L. Albiston, et al. · Journal of Medicinal Chemistry · 50
Direct involvement of the TEN domain at the active site of human telomerase
2010 · Julie Jurczyluk, Amanda S. Nouwens, et al. · Nucleic Acids Research · 49
Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
2015 · Alexandr N. Simonov, Jessica K. Holien, et al. · PLoS ONE · 43
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A structural view of PA2G4 isoforms with opposing functions in cancer
2020 · Brendan W. Stevenson, Michael A. Gorman, et al. · Journal of Biological Chemistry · 41
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Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
2019 · Jessica Koach, Jessica K. Holien, et al. · Cancer Research · 32
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Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability
2022 · Charlotte Hodson, Jason K. K. Low, et al. · Proceedings of the National Academy of Sciences · 31
A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma
2021 · Belamy B. Cheung, Ane Kleynhans, et al. · Oncogene · 30
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Works count: 129
Citation count: 3,179
H-index: 27
I10-index: 47
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