Author

Edwin A. Sagastume

Observed names: Edwin Sagastume, Sagastume, Edwin A.

Institution: Viewpoint Molecular Targeting (United States)

Observed institution: Viewpoint Molecular Targeting (United States)

ORCID: 0000-0002-5911-0381

Observed ORCID: 0000-0002-5911-0381

OpenAlex ID: A5042080583

203/212Pb Theranostic Radiopharmaceuticals for Image-guided Radionuclide Therapy for Cancer

2020 · Mengshi Li, Edwin A. Sagastume, et al. · Current Medicinal Chemistry · 56

Targeted Alpha-Particle Radiotherapy and Immune Checkpoint Inhibitors Induces Cooperative Inhibition on Tumor Growth of Malignant Melanoma

2021 · Mengshi Li, Dijie Liu, et al. · Cancers · 55

Preclinical Evaluation of a Lead Specific Chelator (PSC) Conjugated to Radiopeptides for 203Pb and 212Pb-Based Theranostics

2023 · Mengshi Li, Nicholas J. Baumhover, et al. · Pharmaceutics · 43

Structural modifications toward improved lead-203/lead-212 peptide-based image-guided alpha-particle radiopharmaceutical therapies for neuroendocrine tumors

2023 · Dongyoul Lee, Mengshi Li, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 35

Enhancing the Efficacy of Melanocortin 1 Receptor-Targeted Radiotherapy by Pharmacologically Upregulating the Receptor in Metastatic Melanoma

2019 · Mengshi Li, Dijie Liu, et al. · Molecular Pharmaceutics · 31

Pre-clinical evaluation of biomarkers for the early detection of nephrotoxicity following alpha-particle radioligand therapy

2023 · Mengshi Li, Claudia Robles-Planells, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 11

Lead-it-EAZY! GMP-compliant production of [212Pb]Pb-PSC-PEG2-TOC

2024 · Marc Pretze, Enrico Michler, et al. · EJNMMI Radiopharmacy and Chemistry · 9

Synthesis and evaluation of Diaza-Crown Ether-Backboned chelator containing hydroxamate groups for Zr-89 chelation chemistry

2022 · Shuyuan Zhang, Haixing Wang, et al. · Bioorganic & Medicinal Chemistry Letters · 7

Abstract CT104: MC1R imaging and histology in the targeted imaging of melanoma for alpha-particle radiotherapy (TIMAR1) trial

2023 · Brenna M. Marks, Matthew Block, et al. · Cancer Research · 5

Preclinical evaluation of 203/212Pb-based theranostics-dosimetry and renal toxicity.

2020 · Mengshi Li, Edwin A. Sagastume, et al. · Journal of Nuclear Medicine · 3

Dipicolinic acid (DPA)-based chelators for zirconium-89 PET imaging applications

2026 · Siyuan Ren, Haixing Wang, et al. · Bioorganic & Medicinal Chemistry Letters

Different 212Pb Generators and Its Radiation Safety Concerning 220Rn (Thoron) Emanation

2025 · Marc Pretze, Holger Hartmann, et al. · Toxics

[212Pb]PSC-PEG2-TOC Therapy for NET Leads to Complete Responses in Mice Bearing SSTR2 Positive Tumors - Comparison to [177Lu]DOTATATE in a Preclinical Model

2023 · Michael K. Schultz, Dijie Liu, et al. · Endocrine Abstracts

Abstract 1171: Assessing Melanocortin 1 receptor as a target for metastatic melanoma drug delivery

2021 · Brenna Marks, Mengshi Li, et al. · Cancer Research

Works count: 16

Citation count: 254

H-index: 7

I10-index: 6