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Randolf J. Kerschbaumer

Observed names: Kerschbaumer, Randolf J., R. J. KERSCHBAUMER, R. J. Kerschbaumer, R. Kerschbaumer, R.J. KERSCHBAUMER, R.J. Kerschbaumer, Randolf J Kerschbaumer, Randolf KERSCHBAUMER, Randolf Kerschbaumer
Observed institutions: F. Hoffmann-La Roche AG, University of Vienna, University Hospital of Bern, Baxter (Austria), Takeda (Austria), Medical University of Vienna, BOKU University
ORCID: 0009-0000-9842-5952
Observed ORCID: 0009-0000-9842-5952
OpenAlex ID: A5042240968
Cloning, expression, and functional characterization of the von Willebrand factor–cleaving protease (ADAMTS13)
2002 · Barbara Plaimauer, Klaus Zimmermann, et al. · Blood · 232
Single-Chain Fv Fusion Proteins Suitable as Coating and Detecting Reagents in a Double Antibody Sandwich Enzyme-Linked Immunosorbent Assay
1997 · Randolf J. Kerschbaumer, Sonja Hirschl, et al. · Analytical Biochemistry · 84
Human Anti-Macrophage Migration Inhibitory Factor Antibodies Inhibit Growth of Human Prostate Cancer Cells In Vitro and In Vivo
2013 · Filza Hussain, Michael Freissmuth, et al. · Molecular Cancer Therapeutics · 72
Higher expression of fab antibody fragments in a CHO cell line at reduced temperature
2003 · Simone M. Schatz, Randolf J. Kerschbaumer, et al. · Biotechnology and Bioengineering · 70
Neutralization of Macrophage Migration Inhibitory Factor (MIF) by Fully Human Antibodies Correlates with Their Specificity for the β-Sheet Structure of MIF
2012 · Randolf J. Kerschbaumer, Manfred Rieger, et al. · Journal of Biological Chemistry · 64
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions
2015 · Michael Thiele, Randolf J Kerschbaumer, et al. · The Journal of Immunology · 59
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pSKAP/S: An Expression Vector for the Production of Single-Chain Fv Alkaline Phosphatase Fusion Proteins
1999 · Remko A. Griep, Charlotte van Twisk, et al. · Protein Expression and Purification · 51
A scFv-alkaline phosphatase fusion protein which detects potato leafroll luteovirus in plant extracts by ELISA
1997 · K. Harper, R.J. Kerschbaumer, et al. · Journal of Virological Methods · 50
Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer
2016 · Alexander Schinagl, Michael Thiele, et al. · Oncotarget · 42
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pDAP2: a vector for construction of alkaline phosphatase fusion-proteins
1996 · Randolf J. Kerschbaumer, Sonja Hirschl, et al. · Immunotechnology · 40
Application of Phage Display in Selecting Tomato spotted wilt virus-Specific Single-Chain Antibodies (scFvs) for Sensitive Diagnosis in ELISA
2000 · Remko A. Griep, Marcel Prins, et al. · Phytopathology · 38
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Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch
2018 · Alexander Schinagl, Randolf J. Kerschbaumer, et al. · Biochemistry · 34
Fully “Recombinant Enzyme-Linked Immunosorbent Assays” Using Genetically Engineered Single-Chain Antibody Fusion Proteins for Detection ofCitrus tristeza virus
2000 · Estela Terrada, Randolf J. Kerschbaumer, et al. · Phytopathology · 34
PD-011 Safety and efficacy analysis of imalumab, an anti-oxidized macrophage migration inhibitory factor (oxMIF) antibody, alone or in combination with 5-fluorouracil/leucovorin (5-FU/LV) or panitumumab, in patients with metastatic colorectal cancer (mCRC)
2016 · D. Mahalingam, M. Patel, et al. · Annals of Oncology · 21
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Mutation of the surface‐exposed amino acid Trp2313 to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein
2004 · Simone M. Schatz, Klaus Zimmermann, et al. · British Journal of Haematology · 21
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Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic
2023 · Gregor Rossmueller, Irina Mirkina, et al. · Molecular Cancer Therapeutics · 18
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Improved detection of Beet necrotic yellow vein virus in aDAS ELISA by means of antibody single chain fragments (scFv) which wereselected to protease-stable epitopes from phage display libraries
2000 · K. Uhde, R. J. Kerschbaumer, et al. · Archives of Virology · 15
The newly engineered monoclonal antibody ON104, targeting the oxidized Macrophage Migration Inhibitory Factor (oxMIF), ameliorates clinical and histopathological signs of collagen-induced arthritis
2023 · Maroua Ferhat, Katia Mangano, et al. · European Journal of Pharmacology · 9
Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics
2019 · Patrice Douillard, Michael Freissmuth, et al. · Antibodies · 9
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First-in-human, phase I study assessing imalumab (Bax69), a first-in-class anti-oxidized macrophage migration inhibitory factor (oxMIF) antibody in advanced solid tumors.
2015 · Devalingam Mahalingam, Manish R. Patel, et al. · Journal of Clinical Oncology · 9
Enhancement of the enzymatic activity of activated coagulation factor IX by anti-factor IX antibodies
2008 · F. SCHEIFLINGER, M. DOCKAL, et al. · Journal of Thrombosis and Haemostasis · 8
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Adaptation of Hybridoma Cells to Hydrodynamic Stress Under Continuous Culture Conditions
1992 · Georg Schmid, Francois Huber, et al. · Elsevier eBooks · 8
Pharmacokinetics, disease-modifying activity, and safety of an experimental therapeutic targeting an immunological isoform of macrophage migration inhibitory factor, in rat glomerulonephritis
2017 · Werner Höllriegl, Alexander Bauer, et al. · European Journal of Pharmacology · 7
Enhancement of the enzymatic activity of activated coagulation factor IX by anti-factor IX antibodies
2008 · F. SCHEIFLINGER, M. DOCKAL, et al. · Journal of Thrombosis and Haemostasis · 7
An Antibody Specific for Coagulation Factor IX Enhances the Activity of the Intrinsic Factor X-activating Complex
2004 · Randolf J. Kerschbaumer, Klaudia Riedrich, et al. · Journal of Biological Chemistry · 7
Works count: 98
Citation count: 1,037
H-index: 16
I10-index: 17
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