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Sebastiaan N. J. Laan

Observed names: Laan, Sebastiaan, Sebastiaan Laan, Sebastiaan N.J. Laan
Institution: Leiden University
ORCID: 0000-0001-9206-8712
Observed ORCID: 0000-0001-9206-8712
OpenAlex ID: A5042284659
SYMPHONY consortium: Orchestrating personalized treatment for patients with bleeding disorders
2022 · Marjon H. Cnossen, Marjon H. Cnossen, et al. · Journal of Thrombosis and Haemostasis · 28
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Automated segmentation and quantitative analysis of organelle morphology, localization and content using CellProfiler
2023 · Sebastiaan N. J. Laan, Richard J. Dirven, et al. · PLoS ONE · 21
Uptake and translocation of polystyrene nanoplastics in edible plants via root and foliar exposure: A qualitative imaging-based study
2025 · Juliette Vleeming, Sebastiaan N.J. Laan, et al. · Environmental Pollution · 13
Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs
2025 · Noa A. Linthorst, Yvonne K. Jongejan, et al. · Blood Advances · 12
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Impact of allele-selective silencing of von Willebrand factor in mice based on a single nucleotide allelic difference in von Willebrand factor
2024 · Yvonne K. Jongejan, Noa A. Linthorst, et al. · Thrombosis Research · 12
Endothelial colony-forming cells in the spotlight: insights into the pathophysiology of von Willebrand disease and rare bleeding disorders
2024 · Sebastiaan N.J. Laan, Britte G. Lenderink, et al. · Journal of Thrombosis and Haemostasis · 11
DDAVP response and its determinants in bleeding disorders: a systematic review and meta-analysis
2025 · Sebastiaan Laan, Jessica Del Castillo Alferez, et al. · Blood · 9
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Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endothelial colony forming cells
2024 · Sebastiaan N.J. Laan, Suzan de Boer, et al. · Journal of Thrombosis and Haemostasis · 8
von Willebrand disease-specific defects and proteomic signatures in endothelial colony–forming cells
2025 · Sebastiaan N.J. Laan, Stijn Groten, et al. · Journal of Thrombosis and Haemostasis · 6
Approaches to induce the maturation process of human induced pluripotent stem cell derived-endothelial cells to generate a robust model
2024 · Suzan de Boer, Sebastiaan Laan, et al. · PLoS ONE · 6
A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants
2025 · Sophie Hordijk, Stijn A. Groten, et al. · Blood · 3
Mutated DNMT3A creates a public HLADQ- binding neoantigen on acute myeloid leukemia
2025 · Dyantha I. van der Lee, Eva M. Argiro, et al. · Frontiers in Immunology · 3
Heterozygous nonsense FLI1 p.Met100∗ variant results in thrombocytopenia and increased erythroid gene expression
2025 · Huan Zhang, Elise J. Huisman, et al. · Research and Practice in Thrombosis and Haemostasis · 1
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Ecologically inspired assembly of a Bacillales synthetic community for lignin degradation
2026 · Qing Zhou, Xingchen Xin, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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NVvM Core Facility Day 2026 - Train-the-trainer workshop
2026 · Paul, Maarten W., Laan, Sebastiaan · Zenodo (CERN European Organization for Nuclear Research)
A Novel Cause of Type 1 VWD: Impaired Exocytosis of Weibel-Palade Bodies Due to Biallelic Mutations in Madd
2024 · Sophie Hordijk, Stijn A. Groten, et al. · Blood
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Data for publication "Transcriptional and functional profiling of Endothelial Colony Forming Cells identifies inflammation and endothelial to mesenchymal transition as drivers for phenotypic heterogeneity"
2023 · Laan, Sebastiaan · Zenodo (CERN European Organization for Nuclear Research)
Works count: 19
Citation count: 133
H-index: 8
I10-index: 6
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