Author

Petr Pávek

Observed names: P Pavek, P Pávek, P. PAVEK, P. Pavek, P. PÁVEK, P. Pávek, Pavek, P., Pavek, Petr, Peotr Pavek, Petr Pavek, Petr, Pavek, Pávek, Petr

Institution: Charles University

Observed institutions: Slovak Academy of Sciences, Charles University, Masaryk University, Institute of Experimental Endocrinology of the Slovak Academy of Sciences, Biomedical Research Center of the Slovak Academy of Sciences, Institute of Clinical and Experimental Medicine, Institute of Molecular and Translational Medicine, Palacký University Olomouc, University of Hradec Králové

ORCID: 0000-0001-8769-4196

Observed ORCID: 0000-0001-8769-4196

OpenAlex ID: A5042484633

The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

2019 · Mirko Koziolek, Stefano Alcaro, et al. · European Journal of Pharmaceutical Sciences · 387

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Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes

2012 · Petr Pavek, Lucie Stejskalova, et al. · Frontiers in Pharmacology · 378

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Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues

2008 · Petr Pavek, Zdenek Dvorak · Current Drug Metabolism · 328

Human Breast Cancer Resistance Protein: Interactions with Steroid Drugs, Hormones, the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and Transport of Cimetidine

2004 · Petr Pavek, Gracia Merino, et al. · Journal of Pharmacology and Experimental Therapeutics · 278

Breast cancer resistance protein (BCRP/ABCG2)

2004 · Frantisek Staud, Petr Pavek · The International Journal of Biochemistry & Cell Biology · 232

Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art

2011 · Lucie Stejskalova, Zdenek Dvorak, et al. · Current Drug Metabolism · 231

Valproic Acid Induces CYP3A4 and MDR1 Gene Expression by Activation of Constitutive Androstane Receptor and Pregnane X Receptor Pathways

2007 · Lukas Cerveny, Lucie Svecova, et al. · Drug Metabolism and Disposition · 226

A review on pharmacological activities and synergistic effect of quercetin with small molecule agents

2021 · Haoyang Zou, Haiqing Ye, et al. · Phytomedicine · 208

P-glycoprotein in the placenta: Expression, localization, regulation and function

2006 · Martina Ceckova-Novotna, Petr Pavek, et al. · Reproductive Toxicology · 204

Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions

2016 · Petr Pavek · Frontiers in Pharmacology · 174

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Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

2021 · Zahari Vinarov, Bertil Abrahamsson, et al. · Advanced Drug Delivery Reviews · 150

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The Function of Cytochrome P450 1A1 Enzyme (CYP1A1) and Aryl Hydrocarbon Receptor (AhR) in the Placenta

2011 · Lucie Stejskalova, Petr Pavek · Current Pharmaceutical Biotechnology · 125

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

2016 · Galina Karabanovich, Júlia Zemanová, et al. · Journal of Medicinal Chemistry · 115

Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids

2010 · Zdenek Dvorak, Peotr Pavek · Drug Metabolism Reviews · 115

Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily

2013 · Tomas Smutny, Sridhar Mani, et al. · Current Drug Metabolism · 107

Variation of Drug Kinetics in Pregnancy

2009 · Petr Pavek, Martina Ceckova, et al. · Current Drug Metabolism · 104

Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene

2011 · Lucie Krausova, Lucie Stejskalova, et al. · Biochemical Pharmacology · 96

Expression and Function of P-Glycoprotein in Normal Tissues: Effect on Pharmacokinetics

2009 · Frantisek Staud, Martina Ceckova, et al. · Methods in molecular biology · 92

Metformin induces PGC ‐1α expression and selectively affects hepatic PGC ‐1α functions

2014 · Sanna‐Mari Aatsinki, Marcin Buler, et al. · British Journal of Pharmacology · 85

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Expression and Transport Activity of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Dually Perfused Rat Placenta and HRP-1 Cell Line

2006 · Frantisek Staud, Zuzana Vackova, et al. · Journal of Pharmacology and Experimental Therapeutics · 85

Expression and Functional Activity of Breast Cancer Resistance Protein (bcrp, Abcg2) Transporter in the Human Choriocarcinoma Cell Line Bewo

2006 · Martina Ceckova, Antonin Libra, et al. · Clinical and Experimental Pharmacology and Physiology · 82

Novel Stably Transfected Gene Reporter Human Hepatoma Cell Line for Assessment of Aryl Hydrocarbon Receptor Transcriptional Activity: Construction and Characterization

2011 · Aneta Novotna, Petr, Pavek, et al. · Environmental Science & Technology · 79

Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell lines

2008 · Katerina Pospechova, Veronika Rozehnal, et al. · Molecular and Cellular Endocrinology · 79

Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes

2008 · Radim Vrzal, Lucie Stejskalova, et al. · Chemico-Biological Interactions · 75

JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes

2007 · Zdenek Dvorak, Radim Vrzal, et al. · Biochemical Pharmacology · 75

Works count: 204

Citation count: 7,110

H-index: 47

I10-index: 109