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Toszka Bohn
Observed names:
Bohn, Toszka,
Bohn, Tozka,
Tozka Bohn
Institutions:
Johannes Gutenberg University Mainz,
University Medical Center of the Johannes Gutenberg University Mainz,
Deutsches Konsortium für Translationale Krebsforschung
Observed institutions:
Johannes Gutenberg University Mainz,
University Medical Center,
University Medical Center of the Johannes Gutenberg University Mainz,
Deutsches Konsortium für Translationale Krebsforschung
ORCID:
0009-0009-2738-2807
Observed ORCID:
0009-0009-2738-2807
OpenAlex ID:
A5042505952
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
2018
·
Toszka Bohn
, Steffen Rapp
, et al.
·
Nature Immunology
·
455
Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range
2017
·
Malte Sielaff
, Jörg Kuharev
, et al.
·
Journal of Proteome Research
·
324
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
2019
·
Kathrin Renner
, Christina Bruss
, et al.
·
Cell Reports
·
322
PDF
Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo
2015
·
Alexander Ulges
, Matthias Klein
, et al.
·
Nature Immunology
·
115
CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells
2025
·
Hind Rafei
, Rafet Basar
, et al.
·
Nature
·
76
Protein kinase CK2 governs the molecular decision between encephalitogenic T H 17 cell and T reg cell development
2016
·
Alexander Ulges
, Esther J. Witsch
, et al.
·
Proceedings of the National Academy of Sciences
·
42
PDF
Autonomous Activation of a Gated Chemiluminescent Photosensitizer Enables Targeted Photodynamic Therapy in Tumor Cells
2025
·
Wenwu Peng
, Tianjiao Zhou
, et al.
·
Journal of the American Chemical Society
·
34
Tick Salivary Sialostatin L Represses the Initiation of Immune Responses by Targeting IRF4-Dependent Transcription in Murine Mast Cells
2015
·
Matthias Klein
, Till-Julius Brühl
, et al.
·
The Journal of Immunology
·
34
The effector program of human CD8 T cells supports tissue remodeling
2023
·
Michael Delacher
, Lisa Schmidleithner
, et al.
·
The Journal of Experimental Medicine
·
30
PDF
Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
2021
·
Kerstin Johann
, Toszka Bohn
, et al.
·
Nature Communications
·
29
PDF
Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells
2025
·
Georg Bündgen
, Alexander Ulges
, et al.
·
Immunity
·
23
Abstract 2162: Inhibition of GPR65 counteracts low pH induced immunosuppressive polarization of macrophages: In vitro and in vivo characterization of potent, selective and orally bioavailable small molecule GPR65 antagonists
2022
·
Barbara Cipriani
, David Miller
, et al.
·
Cancer Research
·
8
In Activated Murine Mast Cells, NFATc2 Is Critical for the Production of Autocrine IL-3, Thereby Promoting the Expression of IL-9
2020
·
Farhad Sabbaghi
, Lorenz Ullner
, et al.
·
The Journal of Immunology
·
8
Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization
2025
·
Kaiqi Wu
, Qi Lu
, et al.
·
Advanced Materials
·
6
Role of CD5 signalling for pro-inflammatory Th17 response in multiple sclerosis
2025
·
Katrin Pape
, Nicholas Hanuscheck
, et al.
·
Brain
·
5
PDF
Abstract 668: The translational biology of small molecule GPR65 inhibitors: shared effects between mouse models and human primary tumors highlight the unique transformative potential of targeting a genetically validated innate immune checkpoint
2023
·
Barbara Cipriani
, Alastair Corbin
, et al.
·
Cancer Research
·
3
Solid tumors exploit proton-sensing GPR65 for orchestration of an immunosuppressive tumor microenvironment
2026
·
Tobias Bopp
, Natalia Truong-Andrevici
, et al.
·
Signal Transduction and Targeted Therapy
·
2
PDF
Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
2026
·
Jürgen Brück
, Dominik Schauenburg
, et al.
·
EJNMMI Research
·
2
1324 Inhibition of acid sensing by GPR65 normalises gene expression in macrophages, increases immune cell infiltration in tumors, and restrains subcutaneous MC38 growth in mice
2022
·
Alastair Corbin
, Stuart Hughes
, et al.
·
Journal for ImmunoTherapy of Cancer
·
2
PDF
497 PTT-4256 is a first-in-class small molecule inhibitor of GPR65 that counteracts the low pH-dependent immunosuppressive effects on immune cells and displays pronounced anti-tumor activity in mice
2023
·
Alastair Corbin
, Barbara Cipriani
, et al.
·
Journal for ImmunoTherapy of Cancer
·
1
PDF
Chemically Programmed Albumin–Enzyme Conjugates to Induce Microenvironment-Responsive Metabolic Disruption
2026
·
Lifan Hu
, Yulian Cheng
, et al.
·
ChemRxiv
PDF
Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
2026
·
Brück, Jürgen
, Schauenburg, Dominik
, et al.
·
Figshare
Additional file 1 of Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
2026
·
Brück, Jürgen
, Schauenburg, Dominik
, et al.
·
Figshare
Innate Lymphoid Cell 1– and NK Cell–Derived, Early IFNg Release Depends on ICER and Promotes Protection against Leishmania major Infection
2025
·
Dominika Lukas
, Xinyuan Liu
, et al.
·
Journal of Investigative Dermatology
PDF
Source-data Johann et al..xlsx
2021
·
Johann, Kerstin
, Bohn, Toszka
, et al.
·
Figshare
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Works count:
28
Citation count:
1,521
H-index:
11
I10-index:
11
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