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Jayakumar Narayanan Vadakekolathu

Observed names: J. N. Vadakekolathu, J. Vadakekolathu, Jayakumar Narayanan, Jayakumar Vadakekolathu, Jayakumar Vadakekolathu (5734694), Vadakekolathu, Jayakumar
ORCID: 0000-0002-2671-4285
Observed ORCID: 0000-0002-2671-4285
OpenAlex ID: A5042573600
Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia
2020 · Geoffrey L. Uy, Ibrahim Aldoss, et al. · Blood · 327
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Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia
2020 · Jayakumar Vadakekolathu, Mark D. Minden, et al. · Science Translational Medicine · 217
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TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML
2020 · Jayakumar Vadakekolathu, Catherine Lai, et al. · Blood Advances · 154
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Immune dysfunction signatures predict outcomes and define checkpoint blockade–unresponsive microenvironments in acute myeloid leukemia
2022 · Sergio Rutella, Jayakumar Vadakekolathu, et al. · Journal of Clinical Investigation · 94
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Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts Relapse of Triple Negative Breast Cancer
2018 · Gemma A. Foulds, Jayakumar Vadakekolathu, et al. · Frontiers in Immunology · 77
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Escape from T-cell–targeting immunotherapies in acute myeloid leukemia
2023 · Jayakumar Vadakekolathu, Sergio Rutella · Blood · 73
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Release of IFNγ by Acute Myeloid Leukemia Cells Remodels Bone Marrow Immune Microenvironment by Inducing Regulatory T Cells
2022 · Giulia Corradi, Barbara Bassani, et al. · Clinical Cancer Research · 66
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IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer
2021 · Claudia Tulotta, Diane V. Lefley, et al. · npj Breast Cancer · 64
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A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study
2019 · Sarah Wagner, Jayakumar Vadakekolathu, et al. · Blood Advances · 57
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MiR-423-5p prevents MALAT1-mediated proliferation and metastasis in prostate cancer
2022 · Carmela Ferri, Anna Di Biase, et al. · Journal of Experimental & Clinical Cancer Research · 52
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PYK2 promotes HER2-positive breast cancer invasion
2019 · Shaymaa IK. Al-Juboori, Jayakumar Vadakekolathu, et al. · Journal of Experimental & Clinical Cancer Research · 49
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A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics
2017 · Naomi Harner-Foreman, Jayakumar Vadakekolathu, et al. · Scientific Reports · 46
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Phase 1 Cohort Expansion of Flotetuzumab, a CD123×CD3 Bispecific Dart® Protein in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)
2018 · Geoffrey L. Uy, Michael P. Rettig, et al. · Blood · 41
Nanobugs as Drugs: Bacterial Derived Nanomagnets Enhance Tumor Targeting and Oncolytic Activity of HSV‐1 Virus
2022 · Faith H N Howard, Haider Al‐Janabi, et al. · Small · 40
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Macrophages Mediate the Antitumor Effects of the Oncolytic Virus HSV1716 in Mammary Tumors
2020 · Amy Kwan, Natalie Winder, et al. · Molecular Cancer Therapeutics · 36
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MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer
2018 · Jayakumar Vadakekolathu, Shaymaa Ismael Kadhim Al-Juboori, et al. · Cell Death and Disease · 36
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T-Cell Manipulation Strategies to Prevent Graft-Versus-Host Disease in Haploidentical Stem Cell Transplantation
2017 · Jayakumar Vadakekolathu, Sergio Rutella · Biomedicines · 36
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SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis Insights
2021 · Qiao Zhou, Jayakumar Vadakekolathu, et al. · Frontiers in Immunology · 32
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Novel prostate acid phosphatase‐based peptide vaccination strategy induces antigen‐specific T ‐cell responses and limits tumour growth in mice
2013 · Jaimy M. S. Saif, Jayakumar Vadakekolathu, et al. · European Journal of Immunology · 30
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An IDO1-related immune gene signature predicts overall survival in acute myeloid leukemia
2021 · Simone Ragaini, Sarah Wagner, et al. · Blood Advances · 28
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Flow cytometry and targeted immune transcriptomics identify distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interferon-α
2020 · Raquel Alves, Stephanie E. B. McArdle, et al. · Journal of Translational Medicine · 23
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A Proteomic Approach Reveals That miR-423-5p Modulates Glucidic and Amino Acid Metabolism in Prostate Cancer Cells
2022 · Amalia Luce, Angela Lombardi, et al. · International Journal of Molecular Sciences · 18
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Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein, in Salvage Therapy for Primary Refractory and Early Relapsed Acute Myeloid Leukemia (AML) Patients
2019 · Geoffrey L. Uy, Ibrahim Aldoss, et al. · Blood · 16
Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study
2023 · Darina Ocadlikova, Federico Lussana, et al. · British Journal of Haematology · 14
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Adaptive Immune Gene Signatures Correlate with Response to Flotetuzumab, a CD123 × CD3 Bispecific Dart® Molecule, in Patients with Relapsed/Refractory Acute Myeloid Leukemia
2018 · Sergio Rutella, Sarah E. Church, et al. · Blood · 14
Works count: 143
Citation count: 1,830
H-index: 21
I10-index: 33
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