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Margino Steemans

Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria
2001 · G Denecker, D Vercammen, et al. · Cell Death and Differentiation · 205
A Review of the Implementation of the Embryonic Stem Cell Test (EST)
2009 · Philip Marx-Stoelting, Els Adriaens, et al. · Alternatives to Laboratory Animals · 163
Redox regulation of TNF signaling
1999 · Vera Goossens, Kurt De Vos, et al. · BioFactors · 136
Comparisons betweenin vitrowhole cell imaging andin vivozebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development
2012 · Adrian Hill, Natalie Mesens, et al. · Drug Metabolism Reviews · 101
Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines
2020 · Michael J. Cox, Steffen Jaensch, et al. · Scientific Reports · 61
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Evaluation of the Embryotoxic Potency of Compounds in a Newly Revised High Throughput Embryonic Stem Cell Test
2008 · Annelieke K. Peters, Margino Steemans, et al. · Toxicological Sciences · 46
Assaying embryotoxicity in the test tube: Current limitations of the embryonic stem cell test (EST) challenging its applicability domain
2012 · Christian Riebeling, Katrin Hayess, et al. · Critical Reviews in Toxicology · 40
Optimisation of the cell cultivation methods in the embryonic stem cell test results in an increased differentiation potential of the cells into strong beating myocard cells
2008 · Ann De Smedt, Margino Steemans, et al. · Toxicology in Vitro · 37
Screening for phospholipidosis induced by central nervous drugs: Comparing the predictivity of an in vitro assay to high throughput in silico assays
2010 · Natalie Mesens, Margino Steemans, et al. · Toxicology in Vitro · 36
A 96-well flow cytometric screening assay for detecting in vitro phospholipidosis-induction in the drug discovery phase
2008 · Mesens Natalie, Steemans Margino, et al. · Toxicology in Vitro · 36
A Caspase-activated Factor (CAF) Induces Mitochondrial Membrane Depolarization and Cytochrome c Release by a Nonproteolytic Mechanism
1998 · Margino Steemans, Vera Goossens, et al. · The Journal of Experimental Medicine · 29
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Flow cytometric analysis of micronucleated reticulocytes: Time- and dose-dependent response of known mutagens in mice, using multiple blood sampling
2005 · Marlies De Boeck, Bas-jan van der Leede, et al. · Environmental and Molecular Mutagenesis · 27
Protein Biomarkers for in Vitro Testing of Embryotoxicity
2010 · Karlfried Groebe, Katrin Hayess, et al. · Journal of Proteome Research · 23
Evaluation of chronic drug-induced electrophysiological and cytotoxic effects using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
2023 · C. Altrocchi, K. Van Ammel, et al. · Frontiers in Pharmacology · 20
Unexpected common mechanistic pathways for embryotoxicity of warfarin and lovastatin
2010 · Karlfried Groebe, Katrin Hayess, et al. · Reproductive Toxicology · 15
A higher throughput method to the Embryonic Stem cell Test (EST), to detect embryotoxicity in early development
2008 · Annelieke K. Peters, Margino Steemans, et al. · 12
Protein biomarkers for in vitro testing of embryotoxicity
2009 · André Schrattenholz, Katrin Hayeß, et al. · 2
P16-06: High-content imaging of human hepatic spheroids for studying compounds with cholestatic liability
2023 · B. dos Santos Rodrigues, X. Cendoya Garmendia, et al. · Toxicology Letters
Use of in vitro/in silico cascades for screening potential safety issues in industry
2011 · M. Steemans · Toxicology Letters
Role of Reactive Oxygen Species in Tumor Necrosis Factor Toxicity
2000 · Vera Goossens, Kurt De Vos, et al. · Elsevier eBooks
Contributors
2000 · Valérie Andrieu, Angelo Azzi, et al. · Elsevier eBooks
Works count: 22
Citation count: 989
H-index: 15
I10-index: 16
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