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Giusy Di Conza

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming
2017 · Pu-Ste Liu, Haiping Wang, et al. · Nature Immunology · 1,331
MET is required for the recruitment of anti-tumoural neutrophils
2015 · Veronica Finisguerra, Giusy Di Conza, et al. · Nature · 509
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Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
2013 · Damya Laoui, Eva Van Overmeire, et al. · Cancer Research · 429
Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment
2013 · A Casazza, G Di Conza, et al. · Oncogene · 256
ER Stress Responses: An Emerging Modulator for Innate Immunity
2020 · Giusy Di Conza, Ping-Chih Ho · Cells · 251
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Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity
2021 · Giusy Di Conza, Chin-Hsien Tsai, et al. · Nature Immunology · 220
The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia
2017 · Giusy Di Conza, Sarah Trusso Cafarello, et al. · Cell Reports · 120
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Control of immune cell function by the unfolded protein response
2023 · Giusy Di Conza, Ping-Chih Ho, et al. · Nature reviews. Immunology · 114
MDM4 (MDMX) localizes at the mitochondria and facilitates the p53‐mediated intrinsic‐apoptotic pathway
2009 · Francesca Mancini, Giusy Di Conza, et al. · The EMBO Journal · 83
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Lipid-loaded macrophages as new therapeutic target in cancer
2022 · Giulia Marelli, Nicolò Morina, et al. · Journal for ImmunoTherapy of Cancer · 79
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Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties
2008 · Andrea Prodosmo, Simona Giglio, et al. · Journal of Molecular Medicine · 57
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Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis
2017 · Ward Celus, Giusy Di Conza, et al. · Cell Reports · 56
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CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
2022 · Juan Fernández-García, Fabien Franco, et al. · Cell Reports · 53
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PHD1 regulates p53‐mediated colorectal cancer chemoresistance
2015 · Sofie Deschoemaeker, Giusy Di Conza, et al. · EMBO Molecular Medicine · 48
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MDM4 (MDMX) and its Transcript Variants
2009 · F. Mancini, G. Conza, et al. · Current Genomics · 40
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B55α/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling: A Complementary Approach To Disrupt Pathological Vessels?
2020 · Manuel Ehling, Ward Celus, et al. · Circulation Research · 37
Autotaxin Secretion Is a Stromal Mechanism of Adaptive Resistance to TGFβ Inhibition in Pancreatic Ductal Adenocarcinoma
2023 · Silvia Pietrobono, Fabio Sabbadini, et al. · Cancer Research · 36
IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance
2023 · Zoë Johnson, Chiara Tarantelli, et al. · Cancer Research Communications · 33
Fifty Shades of α-Ketoglutarate on Cellular Programming
2019 · Giusy Di Conza, Chin-Hsien Tsai, et al. · Molecular Cell · 30
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Puzzling over MDM4–p53 network
2010 · F. Mancini, G. Di Conza, et al. · The International Journal of Biochemistry & Cell Biology · 30
PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner
2017 · Giusy Di Conza, Sarah Trusso Cafarello, et al. · Cell Reports · 29
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Characterization and translational development of IOA-289, a novel autotaxin inhibitor for the treatment of solid tumors
2023 · M.A. Deken, K. Niewola-Staszkowska, et al. · Immuno-Oncology Technology · 27
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Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models
2023 · Matteo Centonze, Giusy Di Conza, et al. · Journal of Experimental & Clinical Cancer Research · 23
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A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
2023 · Yao-Wen Chang, Huey-Wen Hsiao, et al. · Cell Reports Medicine · 22
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IGF-1R/MDM2 Relationship Confers Enhanced Sensitivity to RITA in Ewing Sarcoma Cells
2012 · Giusy Di Conza, Marianna Buttarelli, et al. · Molecular Cancer Therapeutics · 22
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Works count: 117
Citation count: 4,089
H-index: 23
I10-index: 31
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