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Jayesh B. Majithiya

Observed names: J MAJITHIYA, J. Majithiya, JB Majithiya, Jayesh B Majithiya, Jayesh Bhanabhai Majithiya, Jayesh Majithiya, Jayesh B. Majithiya
Observed institutions: AstraZeneca (United Kingdom), Maharaja Sayajirao University of Baroda, National Health Service, Manchester Academic Health Science Centre, University of Manchester, National Institute for Health and Care Research, Artios Pharma Limited (United Kingdom)
ORCID: 0000-0003-2944-4871
Observed ORCID: 0000-0003-2944-4871
OpenAlex ID: A5043215310
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
2021 · Diana Zatreanu, Helen M. R. Robinson, et al. · Nature Communications · 397
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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
2015 · E. Suzanne Cohen, Ian C. Scott, et al. · Nature Communications · 284
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Azole Resistance of Aspergillus fumigatus Biofilms Is Partly Associated with Efflux Pump Activity
2011 · Ranjith Rajendran, Eilidh Mowat, et al. · Antimicrobial Agents and Chemotherapy · 161
Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
2023 · Elizabeth England, D. Gareth Rees, et al. · Scientific Reports · 139
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Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage
2018 · Ian C. Scott, Jayesh B. Majithiya, et al. · Scientific Reports · 122
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Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats
2005 · Jayesh B. Majithiya, R. Balaraman · Life Sciences · 116
Pharmacokinetics and Pharmacodynamics of Posaconazole for Invasive Pulmonary Aspergillosis: Clinical Implications for Antifungal Therapy
2011 · Susan J. Howard, Jodi M. Lestner, et al. · The Journal of Infectious Diseases · 108
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Pioglitazone, a PPAR? agonist, restores endothelial function in aorta of streptozotocin-induced diabetic rats
2005 · J MAJITHIYA, A PARAMAR, et al. · Cardiovascular Research · 106
Pharmacokinetics and Pharmacodynamics of a Novel Triazole, Isavuconazole: Mathematical Modeling, Importance of Tissue Concentrations, and Impact of Immune Status on Antifungal Effect
2009 · Peter A. Warn, Andrew Sharp, et al. · Antimicrobial Agents and Chemotherapy · 89
Time-Dependent Changes in Antioxidant Enzymes and Vascular Reactivity of Aorta in Streptozotocin-Induced Diabetic Rats Treated With Curcumin
2005 · Jayesh B Majithiya, R Balaraman · Journal of Cardiovascular Pharmacology · 73
Efficacy of isavuconazole, voriconazole and fluconazole in temporarily neutropenic murine models of disseminated Candida tropicalis and Candida krusei
2008 · J. Majithiya, A. Sharp, et al. · Journal of Antimicrobial Chemotherapy · 64
Pharmacokinetics and Pharmacodynamics of Amphotericin B Deoxycholate, Liposomal Amphotericin B, and Amphotericin B Lipid Complex in an In Vitro Model of Invasive Pulmonary Aspergillosis
2010 · Jodi M. Lestner, Susan J. Howard, et al. · Antimicrobial Agents and Chemotherapy · 55
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta
2022 · Martin L. Stockley, Amanda Ferdinand, et al. · Journal of Medicinal Chemistry · 53
Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
2023 · Gonzalo Rodriguez-Berriguete, Marco Ranzani, et al. · Clinical Cancer Research · 44
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Pharmacodynamics of Voriconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis: Implications for In Vitro Susceptibility Breakpoints
2012 · Adam R. Jeans, Susan J. Howard, et al. · The Journal of Infectious Diseases · 43
Effect of bis[curcumino]oxovanadium complex on non-diabetic and streptozotocin-induced diabetic rats
2005 · Jayesh B. Majithiya, R. Balaraman, et al. · Journal of Trace Elements in Medicine and Biology · 39
Development of a mouse model mimicking key aspects of a viral asthma exacerbation
2013 · Deborah L. Clarke, Nicola H. E. Davis, et al. · Clinical Science · 38
Effect of pioglitazone on l-NAME induced hypertension in diabetic rats
2005 · Jayesh B. Majithiya, Arvind N. Parmar, et al. · Vascular Pharmacology · 29
Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope “tags”
2014 · Jennifer L Percival-Alwyn, Elizabeth England, et al. · mAbs · 22
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Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
2024 · Patrick G. Pilié, Virginia Giuliani, et al. · Clinical Cancer Research · 21
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LATE-BREAKING ABSTRACT: Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
2015 · Suzanne Cohen, Ian Scott, et al. · European Respiratory Journal · 19
Effect of Atorvastatin Treatment on Isoproterenol-Induced Myocardial Infarction in Rats
2006 · Chitrang J. Trivedi, R. Balaraman, et al. · Pharmacology · 15
Effect of curcumin on triton WR 1339 induced hypercholesterolemia in mice
2004 · Jayesh B. Majithiya, Arvind Parmar, et al. · TSpace (University of Toronto) · 11
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Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor
2025 · Sam E. Mann, Julien Lefranc, et al. · Journal of Medicinal Chemistry · 7
Abstract 312: The ATR inhibitor ART0380 shows preclinical efficacy in monotherapy or in combination with gemcitabine, aPD1, PARP inhibitors and topoisomerase 1 poisons
2023 · Jayesh Bhanabhai Majithiya, Marina Roy Luzarraga, et al. · Cancer Research · 4
Works count: 82
Citation count: 2,068
H-index: 20
I10-index: 23
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