Author

Zapporah T. Young

Observed names: Z.T. Young, Zapporah Young, Zapporah T. Young

Institution: University of California, San Francisco

Observed institutions: University of Pittsburgh, University of California, San Francisco, University of South Florida, University of Michigan

ORCID: 0000-0001-8768-0368

Observed ORCID: 0000-0001-8768-0368

OpenAlex ID: A5043300541

Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice

2021 · Benjamin Caballero, Mathieu Bourdenx, et al. · Nature Communications · 220

Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks

2014 · Teresa A. Colvin, Vladimir L. Gabai, et al. · Cancer Research · 179

Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents

2013 · Xiaokai Li, Sharan R. Srinivasan, et al. · ACS Medicinal Chemistry Letters · 154

Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels

2013 · Yoshinari Miyata, Xiaokai Li, et al. · ACS Chemical Neuroscience · 132

Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein–Protein Interactions with Heat Shock Protein 70 (Hsp70)

2018 · Hao Shao, Xiaokai Li, et al. · Journal of Medicinal Chemistry · 111

Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau

2013 · Jose Abisambra, Umesh K. Jinwal, et al. · Biological Psychiatry · 107

Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy

2016 · Zapporah T. Young, Jennifer N. Rauch, et al. · Cell chemical biology · 85

Therapeutic Strategies for Restoring Tau Homeostasis

2017 · Zapporah T. Young, Sue Ann Mok, et al. · Cold Spring Harbor Perspectives in Medicine · 31

A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein–Protein Interactions

2018 · Silvia Rinaldi, Victoria A. Assimon, et al. · ACS Chemical Biology · 27

Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells

2020 · Isabelle R. Taylor, Victoria A. Assimon, et al. · Chemical Science · 21

A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities

2022 · Hao Shao, Shuhei Taguwa, et al. · Cell chemical biology · 13

P3‐178: the Presence of Neuronal Proteins in Human Submandibular Gland in Alzheimer's Disease and Nondemented Individuals

2018 · Zapporah Young, Cristina Armas, et al. · Alzheimer s & Dementia

Chemical Modulators of Heat Shock Protein 70 (Hsp70) Validate this Molecular Chaperone as a Target for Tauopathy

2016 · Zapporah T. Young · Deep Blue (University of Michigan)

Works count: 13

Citation count: 1,080

H-index: 11

I10-index: 11