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Kaleeckal G. Harikumar

Observed names: Harikumar G. Kaleeckal, Harikumar, Kaleeckal G., K G Harikumar, K. G. Harikumar, K.G Harikumar, K.G. Harikumar, Kaleeckal G Harikumar, Kaleeckal Harikumar
Observed institutions: University of Bern, University of Minnesota, Cleveland Clinic, Van Andel Institute, Mayo Clinic, The University of Melbourne, Centre for Cellular and Molecular Biology, Chinese Academy of Sciences, Vanderbilt University, Florey Institute of Neuroscience and Mental Health, Shanghai Institute of Materia Medica, Mayo Clinic in Arizona, University of Chinese Academy of Sciences, Cleveland Clinic Research, National Institute of Nutrition, Monash University
ORCID: 0000-0003-0411-5334
Observed ORCID: 0000-0003-0411-5334
OpenAlex ID: A5006698991
Single-molecule FRET imaging of GPCR dimers in living cells
2021 · Wesley B. Asher, Peter Geggier, et al. · Nature Methods · 210
Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex
2013 · Jiyuan Ke, Kaleeckal G. Harikumar, et al. · Genes & Development · 141
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Dependence of critical micelle concentration of a zwitterionic detergent on ionic strength: implications in receptor solubilization
1996 · Amitabha Chattopadhyay, K.G. Harikumar · FEBS Letters · 129
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Structure of an AMPK complex in an inactive, ATP-bound state
2021 · Yan Yan, Somnath Mukherjee, et al. · Science · 114
Crystal structure of the Frizzled 4 receptor in a ligand-free state
2018 · Shifan Yang, Yiran Wu, et al. · Nature · 113
Transmembrane Segment IV Contributes a Functionally Important Interface for Oligomerization of the Class II G Protein-coupled Secretin Receptor
2007 · Kaleeckal G. Harikumar, Delia I. Pinon, et al. · Journal of Biological Chemistry · 102
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity
2021 · Jesse Mobbs, Matthew J. Belousoff, et al. · PLoS Biology · 85
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Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery
2012 · Kaleeckal G. Harikumar, Denise Wootten, et al. · Proceedings of the National Academy of Sciences · 73
G-Protein-Dependent Cell Surface Dynamics of the Human Serotonin1A Receptor Tagged to Yellow Fluorescent Protein
2004 · Thomas J. Pucadyil, Shanti Kalipatnapu, et al. · Biochemistry · 73
Differential Effects of Modification of Membrane Cholesterol and Sphingolipids on the Conformation, Function, and Trafficking of the G Protein-coupled Cholecystokinin Receptor
2004 · Kaleeckal G. Harikumar, Vishwajeet Puri, et al. · Journal of Biological Chemistry · 69
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Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization
2017 · Zachary J. DeBruine, Jiyuan Ke, et al. · Genes & Development · 68
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Constitutive Formation of Oligomeric Complexes between Family B G Protein-Coupled Vasoactive Intestinal Polypeptide and Secretin Receptors
2005 · Kaleeckal G. Harikumar, Maria M. Morfis, et al. · Molecular Pharmacology · 67
Heterodimerization of Type A and B Cholecystokinin Receptors Enhance Signaling and Promote Cell Growth
2003 · Zhi-Jie Cheng, Kaleeckal G. Harikumar, et al. · Journal of Biological Chemistry · 63
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Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation
2010 · Augen A. Pioszak, Kaleeckal G. Harikumar, et al. · Journal of Biological Chemistry · 61
Induced Association of μ Opioid (MOP) and Type 2 Cholecystokinin (CCK2) Receptors by Novel Bivalent Ligands
2008 · Yaguo Zheng, Eyup Akgün, et al. · Journal of Medicinal Chemistry · 60
Structure and dynamics of the active Gs-coupled human secretin receptor
2020 · Maoqing Dong, Giuseppe Deganutti, et al. · Nature Communications · 56
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Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol
2011 · Ross M. Potter, Kaleeckal G. Harikumar, et al. · Journal of Lipid Research · 55
Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross‐class GPCR heterocomplex
2014 · Leo T. O. Lee, Stephanie Y. L. Ng, et al. · The FASEB Journal · 52
Functional Importance of a Structurally Distinct Homodimeric Complex of the Family B G Protein-Coupled Secretin Receptor
2009 · Fan Gao, Kaleeckal G. Harikumar, et al. · Molecular Pharmacology · 51
Environment and Mobility of a Series of Fluorescent Reporters at the Amino Terminus of Structurally Related Peptide Agonists and Antagonists Bound to the Cholecystokinin Receptor
2002 · Kaleeckal G. Harikumar, Delia I. Pinon, et al. · Journal of Biological Chemistry · 50
Molecular Basis of Association of Receptor Activity-Modifying Protein 3 with the Family B G Protein-Coupled Secretin Receptor
2009 · Kaleeckal G. Harikumar, John Simms, et al. · Biochemistry · 48
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Pattern of Intra-Family Hetero-Oligomerization Involving the G-Protein-Coupled Secretin Receptor
2008 · Kaleeckal G. Harikumar, Maria M. Morfis, et al. · Journal of Molecular Neuroscience · 46
Differential discrimination of G‐protein coupling of serotonin1A receptors from bovine hippocampus by an agonist and an antagonist
1999 · K.G Harikumar, Amitabha Chattopadhyay · FEBS Letters · 46
Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptor
2008 · Kaleeckal G. Harikumar, Renee M. Happs, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 45
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Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus
2004 · Amitabha Chattopadhyay, Md. Jafurulla, et al. · Biochemical and Biophysical Research Communications · 44
Works count: 106
Citation count: 2,896
H-index: 31
I10-index: 66
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