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Jakub M. Swiercz
Observed names:
J. M. Swiercz,
Jakub Swiercz,
Jakub M. Swiercz,
Swiercz, J. M.
Observed institutions:
Goethe University Frankfurt,
Heidelberg University,
Max Planck Institute for Heart and Lung Research,
Gdańsk Medical University
ORCID:
0000-0002-7314-5601
Observed ORCID:
0000-0002-7314-5601
OpenAlex ID:
A5043356723
Plexin-B1 Directly Interacts with PDZ-RhoGEF/LARG to Regulate RhoA and Growth Cone Morphology
2002
·
Jakub M. Swiercz
, Rohini Kuner
, et al.
·
Neuron
·
363
PDF
Sema3E–Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice
2010
·
Andrea Casazza
, Veronica Finisguerra
, et al.
·
Journal of Clinical Investigation
·
196
Plexin-B1/RhoGEF–mediated RhoA activation involves the receptor tyrosine kinase ErbB-2
2004
·
Jakub M. Swiercz
, Rohini Kuner
, et al.
·
The Journal of Cell Biology
·
163
ErbB-2 and Met Reciprocally Regulate Cellular Signaling via Plexin-B1
2007
·
Jakub M. Swiercz
, Thomas Worzfeld
, et al.
·
Journal of Biological Chemistry
·
139
Plexin-B2, But Not Plexin-B1, Critically Modulates Neuronal Migration and Patterning of the Developing Nervous System In Vivo
2007
·
S. Deng
, A. Hirschberg
, et al.
·
Journal of Neuroscience
·
124
PDF
A Molecular Basis of Analgesic Tolerance to Cannabinoids
2007
·
Anke Tappe-Theodor
, Nitin Agarwal
, et al.
·
Journal of Neuroscience
·
116
PDF
Association of axon guidance factor Semaphorin 3A with poor outcome in pancreatic cancer
2007
·
Michael W. Müller
, Nathalia A. Giese
, et al.
·
International Journal of Cancer
·
103
PDF
ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis
2012
·
Thomas Worzfeld
, Jakub M. Swiercz
, et al.
·
Journal of Clinical Investigation
·
94
PDF
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction
2013
·
Tatyana Novoyatleva
, Yves Schymura
, et al.
·
Basic Research in Cardiology
·
74
PDF
Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair
2015
·
Jingjing Xia
, Jakub M. Swiercz
, et al.
·
Developmental Cell
·
70
PDF
Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate
2015
·
Ramesh K. Krishnan
, Hendrik Nolte
, et al.
·
Nature Communications
·
65
PDF
Genetic dissection of plexin signaling in vivo
2014
·
Thomas Worzfeld
, Jakub M. Swiercz
, et al.
·
Proceedings of the National Academy of Sciences
·
64
Modulation of the activity of calcium-activated neutral proteases (calpains) in chronic lymphocytic leukemia (B-CLL) cells
2002
·
Jacek M. Witkowski
, Emilia Zmuda-Trzebiatowska
, et al.
·
Blood
·
63
Characterization of the expression of PDZ‐RhoGEF, LARG and Gα12/Gα13 proteins in the murine nervous system
2002
·
R. Kuner
, J. M. Swiercz
, et al.
·
European Journal of Neuroscience
·
49
The semaphorin 4D‐plexin‐B signalLing complex regulates dendritic and axonal complexity in developing neurons via diverse pathways
2009
·
Peter Vodrazka
, Alexander Korostylev
, et al.
·
European Journal of Neuroscience
·
48
A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis
2008
·
Alexander Korostylev
, Thomas Worzfeld
, et al.
·
Development
·
48
ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation
2013
·
Cathrin Herder
, Jakub M. Swiercz
, et al.
·
Development
·
45
A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib
2016
·
Tianliang Sun
, Lida Yang
, et al.
·
The Journal of Cell Biology
·
43
PDF
Semaphorin 4D Signaling Requires the Recruitment of Phospholipase Cγ into the Plexin-B1 Receptor Complex
2009
·
Jakub M. Swiercz
, Thomas Worzfeld
, et al.
·
Molecular and Cellular Biology
·
38
Endothelial Gαq/11is required for VEGF-induced vascular permeability and angiogenesis
2015
·
Kishor K. Sivaraj
, Rui Li
, et al.
·
Cardiovascular Research
·
29
Grb2 mediates semaphorin-4D-dependent RhoA inactivation
2012
·
Tianliang Sun
, Rameshkumar Krishnan
, et al.
·
Journal of Cell Science
·
21
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers
2022
·
Rui Xu
, Carsten Höß
, et al.
·
Science Translational Medicine
·
12
Abstract LB-291: EOS100850, an insurmountable and non-brain penetrant A2A receptor antagonist, inhibits adenosine-mediated T cell suppression, demonstrates anti-tumor activity and exhibits best-in class characteristics
2018
·
Erica Houthuys
, Reece Marillier
, et al.
·
Cancer Research
·
10
Abstract 1683: A novel adenosine A2A receptor antagonist optimized for high potency in adenosine-rich tumor microenvironment boosts antitumor immunity
2017
·
Erica Houthuys
, Margreet Brouwer
, et al.
·
Cancer Research
·
9
Abstract 3261: EOS100850, a non-brain penetrant highly selective A2Areceptor antagonist, uniquely maintains high potency within the adenosine rich tumor microenvironment
2019
·
Erica Houthuys
, Paola Basilico
, et al.
·
Cancer Research
·
6
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Works count:
37
Citation count:
2,002
H-index:
21
I10-index:
23
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