Author

Marilynn Vetzel

Observed names: M Vetzel, Marilynn R. Vetzel

Observed institutions: Purdue University West Lafayette, Endocyte (United States)

OpenAlex ID: A5043457997

Synthesis and Biological Evaluation of EC20: A New Folate-Derived, 99mTc-Based Radiopharmaceutical

2002 · Christopher P. Leamon, Matthew A. Parker, et al. · Bioconjugate Chemistry · 212

Preclinical Evaluation of EC145, a Folate- Vinca Alkaloid Conjugate

2007 · Joseph A. Reddy, Ryan Dorton, et al. · Cancer Research · 183

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Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors.

2004 · Joseph A Reddy, Le-Cun Xu, et al. · PubMed · 113

Preclinical Antitumor Activity of a Novel Folate-Targeted Dual Drug Conjugate

2007 · Christopher P. Leamon, Joseph A. Reddy, et al. · Molecular Pharmaceutics · 111

Folate Targeting Enables Durable and Specific Antitumor Responses from a Therapeutically Null Tubulysin B Analogue

2008 · Christopher P. Leamon, Joseph A. Reddy, et al. · Cancer Research · 96

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Synthesis and Biological Evaluation of EC72: A New Folate-Targeted Chemotherapeutic

2005 · Christopher P. Leamon, Joseph A. Reddy, et al. · Bioconjugate Chemistry · 94

Folate Receptor–Specific Antitumor Activity of EC131, a Folate-Maytansinoid Conjugate

2007 · Joseph A. Reddy, Elaine Westrick, et al. · Cancer Research · 83

Comparative preclinical activity of the folate‐targeted Vinca alkaloid conjugates EC140 and EC145

2007 · Christopher P. Leamon, Joseph A. Reddy, et al. · International Journal of Cancer · 82

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Folate–Vinca Alkaloid Conjugates for Cancer Therapy: A Structure–Activity Relationship

2014 · Christopher P. Leamon, Iontcho R. Vlahov, et al. · Bioconjugate Chemistry · 72

Preclinical Evaluation of Bispecific Adaptor Molecule Controlled Folate Receptor CAR-T Cell Therapy With Special Focus on Pediatric Malignancies

2019 · Yingjuan J. Lu, Haiyan Chu, et al. · Frontiers in Oncology · 63

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In Vivo Structural Activity and Optimization Studies of Folate−Tubulysin Conjugates

2009 · Joseph A. Reddy, Ryan Dorton, et al. · Molecular Pharmaceutics · 63

Synthesis and Biological Evaluation of EC140: A Novel Folate-Targeted Vinca Alkaloid Conjugate

2006 · Christopher P. Leamon, Joseph A. Reddy, et al. · Bioconjugate Chemistry · 58

Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic

2018 · Joseph A. Reddy, Ryan Dorton, et al. · Scientific Reports · 51

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Reducing Undesirable Hepatic Clearance of a Tumor-Targeted Vinca Alkaloid via Novel Saccharopeptidic Modifications

2010 · Christopher P. Leamon, Joseph A. Reddy, et al. · Journal of Pharmacology and Experimental Therapeutics · 48

Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate

2019 · Christopher P. Leamon, Joseph A. Reddy, et al. · Bioconjugate Chemistry · 43

Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate–targeted immunotherapy in hapten-immunized mice

2006 · Yingjuan Lu, Le-Cun Xu, et al. · Molecular Cancer Therapeutics · 35

Rational Combination Therapy of Vintafolide (EC145) with Commonly Used Chemotherapeutic Drugs

2014 · Joseph A. Reddy, Ryan Dorton, et al. · Clinical Cancer Research · 26

High Levels of Expression of P-glycoprotein/Multidrug Resistance Protein Result in Resistance to Vintafolide

2016 · Amy D. Guertin, Jennifer O'Neil, et al. · Molecular Cancer Therapeutics · 21

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Acid mediated formation of an N-acyliminium ion from tubulysins: A new methodology for the synthesis of natural tubulysins and their analogs

2011 · Iontcho R. Vlahov, Yu Wang, et al. · Bioorganic & Medicinal Chemistry Letters · 18

Latent Warheads for Targeted Cancer Therapy: Design and Synthesis of pro-Pyrrolobenzodiazepines and Conjugates

2017 · Iontcho R. Vlahov, Longwu Qi, et al. · Bioconjugate Chemistry · 17

Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy

2017 · Christopher P. Leamon, Joseph A. Reddy, et al. · Cancer Chemotherapy and Pharmacology · 15

Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent

2020 · Joseph A. Reddy, Melissa Nelson, et al. · Scientific Reports · 12

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Abstract 832: Pre-clinical development of EC1456: A potent Folate targeted Tubulysin SMDC

2014 · Joseph A. Reddy, Alicia Bloomfield, et al. · Cancer Research · 7

Abstract 2145: PSMA-specific anti-tumor activity of the targeted-tubulysin conjugate, EC1169.

2013 · Joseph A. Reddy, Alicia Bloomfield, et al. · Cancer Research · 6

Abstract LB-109: Adaptor controlled CAR-T cell immunotherapy for treatment of folate receptor-alpha/beta positive solid and liquid tumors

2018 · Yingjuan June Lu, Haiyan Chu, et al. · Cancer Research · 2

Works count: 47

Citation count: 1,537

H-index: 18

I10-index: 22