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Jeff Y. L. Lam

Observed names: Jeff Lam, Jeff Y L Lam, Jeff Y.L. Lam, Jeff YL Lam, Jeff Yui Long Lam, Lam, Jeff YL
ORCID: 0000-0001-7408-2342
Observed ORCID: 0000-0001-7408-2342
OpenAlex ID: A5043611357
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
2022 · Derya Emin, Yu P. Zhang, et al. · Nature Communications · 221
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Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease
2021 · Evgeniia Lobanova, Daniel Whiten, et al. · Brain · 64
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Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease
2024 · Zengjie Xia, Emily E. Prescott, et al. · Nature Communications · 62
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Electrochemical Behavior of Thiocarbonylthio Chain Transfer Agents for RAFT Polymerization
2019 · Lisa T. Strover, Alexis Cantalice, et al. · ACS Macro Letters · 53
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
2025 · Emre Fertan, Jeff Y. L. Lam, et al. · Alzheimer s & Dementia · 39
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Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging
2022 · John S. H. Danial, Jeff Y. L. Lam, et al. · Nature Protocols · 39
Single‐Molecule Characterization and Super‐Resolution Imaging of Alzheimer's Disease‐Relevant Tau Aggregates in Human Samples
2024 · Dorothea Böken, Dezerae Cox, et al. · Angewandte Chemie International Edition · 38
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Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
2023 · Eleni Dimou, Taxiarchis Katsinelos, et al. · Cell Reports · 38
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Cerebral organoids with chromosome 21 trisomy secrete Alzheimer’s disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy
2023 · Emre Fertan, Dorothea Böken, et al. · Molecular Psychiatry · 30
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Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform
2024 · Dorothea Böken, Zengjie Xia, et al. · Analytical Chemistry · 25
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Imaging G-Quadruplex Nucleic Acids in Live Cells Using Thioflavin T and Fluorescence Lifetime Imaging Microscopy
2024 · Tigerlily Bradford, Peter A. Summers, et al. · Analytical Chemistry · 24
Clearance of beta-amyloid and tau aggregates is size dependent and altered by an inflammatory challenge
2024 · Emre Fertan, Christy Hung, et al. · Brain Communications · 15
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A computational suite for the structural and functional characterization of amyloid aggregates
2023 · Zengjie Xia, Yunzhao Wu, et al. · Cell Reports Methods · 13
An economic, square-shaped flat-field illumination module for TIRF-based super-resolution microscopy
2022 · Jeff Y.L. Lam, Yunzhao Wu, et al. · Biophysical Reports · 13
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Detection of p53 aggregates in plasma of glioma patients
2025 · Yunzhao Wu, Jeff Y. L. Lam, et al. · Communications Medicine · 9
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Nanoscopic tau aggregates are not shared intermediates but disease-specific entities across tauopathies
2026 · Dorothea Böken, Melissa Huang, et al. · Cell Reports · 6
SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
2025 · Shekhar Kedia, Emre Fertan, et al. · Cell chemical biology · 6
Detecting alpha-synuclein aggregates with small molecules on single-molecule array
2025 · Jeff Y. L. Lam, Timothy S. Chisholm, et al. · Chemical Science · 4
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Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
2024 · Emre Fertan, Jeff Y. L. Lam, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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Single‐Molecule Characterization and Super‐Resolution Imaging of Alzheimer's Disease‐Relevant Tau Aggregates in Human Samples
2024 · Dorothea Böken, Dezerae Cox, et al. · Angewandte Chemie · 4
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A p16 pathway to prevention: Senescence as a driver of tau-mediated neurodegeneration
2025 · Jeff Y.L. Lam, Kai Wang, et al. · Neuron · 2
Small tau aggregates exhibit disease-specific molecular profiles across tauopathies
2025 · Dorothea Böken, Melissa Huang, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
Correction to “Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform”
2025 · Dorothea Böken, Zengjie Xia, et al. · Analytical Chemistry · 1
Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
2024 · David Klenerman, Emre Fertan, et al. · Research Square · 1
Breaking the glial loop: astrocytic PAD2 and citrullinated vimentin drive microglial dysfunction in Alzheimer’s disease
2026 · Jeff Y. L. Lam, Guojun Bu · Molecular Neurodegeneration
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Works count: 36
Citation count: 713
H-index: 13
I10-index: 14
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