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Author

Alexander Pietras

Observed names: A Pietras, Pietras, Alexander
Observed institutions: Uppsala University, Memorial Sloan Kettering Cancer Center, Universitat de València, Lund University, University of Washington, Karolinska Institutet, Medicon Village, Fred Hutch Cancer Center, Skåne University Hospital
ORCID: 0000-0002-5783-9347
Observed ORCID: 0000-0002-5783-9347
OpenAlex ID: A5043770726
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
2006 · Linda Holmquist-Mengelbier, Erik Fredlund, et al. · Cancer Cell · 761
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Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth
2014 · Alexander Pietras, Amanda M. Katz, et al. · Cell stem cell · 559
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Hypoxia Inducible Factor-2α in Cancer
2007 · Tobias Löfstedt, Erik Fredlund, et al. · Cell Cycle · 194
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Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
2008 · Jonas Sjölund, Martin Johansson, et al. · Journal of Clinical Investigation · 184
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HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
2009 · Alexander Pietras, Loen M. Hansford, et al. · Proceedings of the National Academy of Sciences · 133
CD44 Interacts with HIF-2α to Modulate the Hypoxic Phenotype of Perinecrotic and Perivascular Glioma Cells
2017 · Elinn Johansson, Elisa S. Grassi, et al. · Cell Reports · 122
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High levels of HIF‐2α highlight an immature neural crest‐like neuroblastoma cell cohort located in a perivascular niche
2008 · A Pietras, D Gisselsson, et al. · The Journal of Pathology · 116
Cancer Stem Cells in Tumor Heterogeneity
2011 · Alexander Pietras · Advances in cancer research · 88
HIF-1α and HIF-2α Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization
2009 · Rosa Noguera, Erik Fredlund, et al. · Clinical Cancer Research · 81
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Recruited Cells Can Become Transformed and Overtake PDGF-Induced Murine Gliomas In Vivo during Tumor Progression
2011 · Elena I. Fomchenko, Joseph D. Dougherty, et al. · PLoS ONE · 77
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JAG2 Induction in Hypoxic Tumor Cells Alters Notch Signaling and Enhances Endothelial Cell Tube Formation
2011 · Alexander Pietras, Kristoffer von Stedingk, et al. · Molecular Cancer Research · 73
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Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells
2022 · Tracy J. Berg, Alexander Pietras · Seminars in Cancer Biology · 66
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The HIF-2α-Driven Pseudo-Hypoxic Phenotype in Tumor Aggressiveness, Differentiation, and Vascularization
2010 · Alexander Pietras, A. Sofie Johnsson, et al. · Current topics in microbiology and immunology · 63
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ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
2016 · Boyoung Wee, Alexander Pietras, et al. · Scientific Reports · 62
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Emerging Roles of DLK1 in the Stem Cell Niche and Cancer Stemness
2021 · Elisa Stellaria Grassi, Alexander Pietras · Journal of Histochemistry & Cytochemistry · 59
Protumoral lipid droplet–loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted
2024 · Valeria Governa, Kelin Gonçalves de Oliveira, et al. · Science Translational Medicine · 56
The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2
2021 · Tracy J. Berg, Carolina Marques, et al. · Cancer Research · 51
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Hypoxia-induced complement component 3 promotes aggressive tumor growth in the glioblastoma microenvironment
2024 · Rebecca Rosberg, Karolina I. Smolag, et al. · JCI Insight · 44
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma
2020 · Elisa Stellaria Grassi, Vasiliki Pantazopoulou, et al. · Oncogene · 40
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Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells
2009 · Helen M. Pettersson, Alexander Pietras, et al. · Molecular Cancer Therapeutics · 38
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Hypoxia-Induced Reactivity of Tumor-Associated Astrocytes Affects Glioma Cell Properties
2021 · Vasiliki Pantazopoulou, Pauline Jeannot, et al. · Cells · 37
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The p75 neurotrophin receptor enhances HIF-dependent signaling in glioma
2018 · Bei Tong, Vasiliki Pantazopoulou, et al. · Experimental Cell Research · 23
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Arsenic trioxide and neuroblastoma cytotoxicity
2007 · Helen M. Pettersson, Jenny Karlsson, et al. · Journal of Bioenergetics and Biomembranes · 22
Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma
2025 · Sebastian Braun, Paulina Bolivar, et al. · Nature Communications · 21
Niche-derived soluble DLK1 promotes glioma growth
2020 · Elisa S. Grassi, Pauline Jeannot, et al. · Neoplasia · 20
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Works count: 99
Citation count: 3,074
H-index: 22
I10-index: 30
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