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TEXY K. JACOB
Observed name:
Texy Jacob
Institution:
Dasman Diabetes Institute
Observed institution:
Dasman Diabetes Institute
ORCID:
0000-0002-1413-9535
Observed ORCID:
0000-0002-1413-9535
OpenAlex ID:
A5043960630
IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 Acetylation
2021
·
Areej Al-Roub
, Ashraf Al Madhoun
, et al.
·
Cells
·
66
PDF
Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway
2020
·
Fatema Al-Rashed
, Sardar Sindhu
, et al.
·
Cells
·
64
PDF
ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding
2023
·
Fatema Al-Rashed
, Dania Haddad
, et al.
·
iScience
·
36
PDF
TGF-β and TNF-α interaction promotes the expression of MMP-9 through H3K36 dimethylation: implications in breast cancer metastasis
2024
·
Shihab Kochumon
, Amnah Al-Sayyar
, et al.
·
Frontiers in Immunology
·
34
PDF
Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
2020
·
Shihab Kochumon
, Hossein Arefanian
, et al.
·
Biomedicines
·
32
PDF
Gut Dysbiosis Shaped by Cocoa Butter-Based Sucrose-Free HFD Leads to Steatohepatitis, and Insulin Resistance in Mice
2024
·
Shihab Kochumon
, Md. Zubbair Malik
, et al.
·
Nutrients
·
24
Increased Adipose Tissue Expression of IL-23 Associates with Inflammatory Markers in People with High LDL Cholesterol
2022
·
Shihab Kochumon
, Amal Hasan
, et al.
·
Cells
·
24
Palmitate Potentiates Lipopolysaccharide-Induced IL-6 Production via Coordinated Acetylation of H3K9/H3K18, p300, and RNA Polymerase II
2022
·
Shihab Kochumon
, Texy Jacob
, et al.
·
The Journal of Immunology
·
20
TNF-α Increases IP-10 Expression in MCF-7 Breast Cancer Cells via Activation of the JNK/c-Jun Pathways
2021
·
Shihab Kochumon
, Amnah Al-Sayyar
, et al.
·
Biomolecules
·
17
PDF
Soybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice
2024
·
Texy Jacob
, Sardar Sindhu
, et al.
·
Frontiers in Microbiology
·
14
PDF
Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity
2022
·
Shihab Kochumon
, Hossein Arefanian
, et al.
·
Cells
·
11
PDF
IL-1β-Induced CXCL10 Expression in THP-1 Monocytic Cells Involves the JNK/c-Jun and NF-κB-Mediated Signaling
2024
·
Shihab Kochumon
, Amnah Al-Sayyar
, et al.
·
Pharmaceuticals
·
10
Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation
2024
·
Fatema Al-Rashed
, Hossein Arefanian
, et al.
·
Cells
·
9
PDF
Differential effects of fish-oil and cocoa-butter based high-fat/high-sucrose diets on endocrine pancreas morphology and function in mice
2024
·
Shaima Albeloushi
, Amal Hasan
, et al.
·
Frontiers in Endocrinology
·
3
PDF
162-OR: Sustained TNF-a Transcription Triggered in Obesity through H3K9/K18 Acetylation Is Associated with Metabolic Impairments
2024
·
RASHEED AHMAD
, FATEMAH BAHMAN
, et al.
·
Diabetes
·
2
Sucrose-free low-fat diet induces metabolic dysfunction through gut dysbiosis and colonic inflammation in mice
2026
·
Nourah Almansour
, Shihab Kochumon
, et al.
·
Frontiers in Immunology
2412-P: Inhibition of Histone Acetylation Protects against TNF-α–Mediated Metabolic Inflammation
2026
·
FATEMAH BAHMAN
, SHIHAB KOCHUMON
, et al.
·
Diabetes
2475-P: TLR2-Selective Agonism Reverses and Prevents Hepatic Steatosis in Diet-Induced Obese Mice
2026
·
SHIHAB KOCHUMON
, FATEMA ALRASHED
, et al.
·
Diabetes
TLR4 Deficiency Fails to Protect Against Diet-Induced Behavioral Impairments Under High-Sucrose Feeding
2025
·
Ghadeer Alhamar
, Rawan Najem
, et al.
·
Research Square
PDF
209-OR: TLR2 Deficiency Induces Hepatic Steatosis through the PPAR-γ-CD36 Pathway
2025
·
RASHEED AHMAD
, SHIHAB P. KOCHUMON
, et al.
·
Diabetes
193-OR: IL-6 Deficiency Mitigates Metabolic Dysregulation in Mice via CXCL14-Driven Inflammation Reduction in Adipose and Liver Tissues
2025
·
RASHEED AHMAD
, SHIHAB P. KOCHUMON
, et al.
·
Diabetes
1737-P: Pharmacological Inhibition of Acyl-CoA Synthetase as a Novel Strategy for Weight Reduction and Metabolic Health Improvement
2025
·
FATEMA ALRASHED
, HALEMAH ALSAEED
, et al.
·
Diabetes
1603-P: Differential Effects of Cocoa Butter, Sunflower, Soybean, and Fish Oil Based Sucrose-Free HFDs on Hepatic Steatosis, Lipogenesis, Inflammation, and Insulin Resistance in Mice
2023
·
RASHEED AHMAD
, TEXY K. JACOB
, et al.
·
Diabetes
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Works count:
23
Citation count:
366
H-index:
11
I10-index:
12
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