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Blaine Rathmann

Observed names: BLAINE RATHMANN, Blaine T Rathmann, Rathmann Blaine
OpenAlex ID: A5044076192
Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial
2025 · Emil Lou, Modassir S Choudhry, et al. · The Lancet Oncology · 62
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
2023 · Beau R. Webber, Matthew J. Johnson, et al. · Nature Biomedical Engineering · 27
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Immune Pharmacodynamic Responses of the Novel Cancer Immunotherapeutic Imprime PGG in Healthy Volunteers
2019 · Nandita Bose, Nadine R Ottoson, et al. · The Journal of Immunology · 14
Immunoglobulin Restores Immune Responses to BTH1677 in Patients With Low Levels of Antibodies to Beta-glucan
2020 · PETER J. HURLEY, NANDITA BOSE, et al. · Anticancer Research · 4
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Abstract LB-087: Imprime PGG drives adaptive immune resistance within the tumor microenvironment by modulating the myeloid compartment and enhances the efficacy of anti-PD1 antibody in vivo
2016 · Adria L. Bykowski Jonas, Anissa SH Chan, et al. · Cancer Research · 4
Abstract CT269: First-in-human trial in patients with metastatic colorectal cancer using CRISPR-engineered tumor infiltrating lymphocytes in which the intracellular immune checkpoint CISH is inhibited
2025 · Emil Lou, Modassir S. Choudhry, et al. · Cancer Research · 1
A multicenter, open-label, phase 2 study of odetiglucan (IMPRIME PGG) and pembrolizumab in patients with metastatic breast cancer (mBCA) who have progressed through prior hormonal therapy.
2022 · Alison Stopeck, Michele Anne Gargano, et al. · Journal of Clinical Oncology · 1
A multicenter, open-label, phase 1a/b study of HC-7366, a modulator of integrated stress response (ISR) kinase GCN2 in subjects with advanced solid tumors.
2022 · Meredith Pelster, Marcio Torre, et al. · Journal of Clinical Oncology · 1
Homology mediated end joining enables efficient non-viral targeted integration of large DNA templates in primary human T cells
2021 · Beau R. Webber, Matthew J. Johnson, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Effect of imprime PGG on innate immune-activating pharmacodynamic changes in a phase I clinical study in healthy human volunteers.
2017 · Nandita Bose, Nadine Ottoson, et al. · Journal of Clinical Oncology · 1
35 Targeted non-viral integration of large cargo in primary human T cells by CRISPR/Cas9 guided homology mediated end joining
2020 · Beau Webber, Matthew Johnson, et al. · Regular and Young Investigator Award Abstracts
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Abstract B008: Imprime PGG, an intravenously administered beta glucan PAMP activates the innate immune system: A phase I clinical study to evaluate immunopharmacodynamic responses
2016 · Nadine C. Ottoson, Richard D. Huhn, et al. · Cancer Immunology Research
Translational Repression Mediated By the Genotoxic Agent Sodium Dichromate Results in P‐body Formation in S. cerevisiae
2013 · Whitney Leigh Hopfauf, Chris Bullard, et al. · The FASEB Journal
A Novel Mechanism for Recognition of a Small Molecule Carbohydrate Immunotherapeutic by Human Myeloid Cells: Potential for Modulation of Efficacy in the Clinic
2013 · Antonysamy Mary, Nelson Mariana, et al. · Frontiers in Immunology
Genotoxic Stress Results in Selective P‐body Formation in S. cerevisiae
2012 · Scott P. Segal, Blaine Rathmann, et al. · The FASEB Journal
Works count: 15
Citation count: 116
H-index: 4
I10-index: 3
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